P. T. Curtin

Publication List Details

Number

6

Co-Authors

A 24-base-pair sequence 3' to the human erythropoietin gene contains a hypoxia-responsive transcriptional enhancer.

Madan, A, Curtin, P T

Erythropoietin (Epo) synthesis increases in response to hypoxia. The hepatoma cell line Hep 3B produces low basal levels of Epo mRNA which increase markedly with hypoxia. To define the sequences...

Human beta-globin gene expression in transgenic mice is enhanced by a distant DNase I hypersensitive site.

Curtin, P T, Liu, D P, Liu, W, Chang, J C, Kan, Y W

Several lines of evidence suggest that erythroid-specific DNase I hypersensitive sites (HS) located far upstream of the human beta-globin gene are important in regulating beta-globin gene expression....

Dissection of the enhancer activity of beta-globin 5' DNase I-hypersensitive site 2 in transgenic mice.

Liu, D, Chang, J C, Moi, P, Liu, W, Kan, Y W, Curtin, P T

The beta-globin locus control region (LCR) consists of four erythroid-specific DNase I-hypersensitive sites, which are necessary for high-level expression of the beta-like globin genes in erythroid...

A 24-base-pair sequence 3' to the human erythropoietin gene contains a hypoxia-responsive transcriptional enhancer.

Madan, A, Curtin, P T

Erythropoietin (Epo) synthesis increases in response to hypoxia. The hepatoma cell line Hep 3B produces low basal levels of Epo mRNA which increase markedly with hypoxia. To define the sequences...

Human beta-globin gene expression in transgenic mice is enhanced by a distant DNase I hypersensitive site.

Curtin, P T, Liu, D P, Liu, W, Chang, J C, Kan, Y W

Several lines of evidence suggest that erythroid-specific DNase I hypersensitive sites (HS) located far upstream of the human beta-globin gene are important in regulating beta-globin gene expression....

Dissection of the enhancer activity of beta-globin 5' DNase I-hypersensitive site 2 in transgenic mice.

Liu, D, Chang, J C, Moi, P, Liu, W, Kan, Y W, Curtin, P T

The beta-globin locus control region (LCR) consists of four erythroid-specific DNase I-hypersensitive sites, which are necessary for high-level expression of the beta-like globin genes in erythroid...