P. Th A. Schellekens

Publication List Details

Period

1979 - 1979

Number

6

Co-Authors

Failure of lymphocyte-membrane HLA-A and -B expression in two siblings with combined immunodeficiency (1979)

Schuurman, R.K.B., Rood, J.J. Van, Vossen, J.M., Schellekens, P.Th.A., Feltkamp-Vroom, Th.M., Doyer, E., ...

A diagnosis of partial combined immunodeficiency was made in two Turkish siblings with a history of multiple pyogenic infections and persistent candidiasis. They demonstrated severe...

Lymphocyte transformation in vitro. I. Tissue culture conditions and quantitative measurements

Schellekens, P. Th. A., Eijsvoogel, V. P.

The quantitative evaluation of the reactivity in human PHA-stimulated lymphocyte cultures was studied. A technique for the measurement of DNA synthesis by means of thymidine-2-14C incorporation was...

Lymphocyte transformation in vitro. II. Mixed lymphocyte culture in relation to leucocyte antigens

Schellekens, P. Th. A., Vriesendorp, Birgitta, Eijsvoogel, V. P., Van Leeuwen, Aad, Van Rood, J. J., Miggiano, V., ...

By means of family studies the relation between leucocyte antigens and reactivity in mixed lymphocyte culture was investigated.

Lymphocyte transformation in vitro. III. Mechanism of stimulation in the mixed lymphocyte culture

Schellekens, P. Th. A., Eijsvoogel, V. P.

In view of the correlation between the mixed lymphocyte culture and the HL-A locus, experiments were performed to determine whether the reactivity in the mixed lymphocyte culture is elicited by the...

Lymphocyte transformation in vitro. IV. Recruitment on antigen stimulated cultures

Schellekens, P. Th. A., Eijsvoogel, V. P.

The additive effect of two or three different antigens upon the total DNA synthesis in lymphocyte transformation in vitro was investigated. Evidence was obtained that definite, but incomplete...

Low T cell reactivity to combined CD3 plus CD28 stimulation is predictive for progression to AIDS: correlation with decreased CD28 expression

ROOS, M TH L, MIEDEMA, F, MEINESZ, A A P, PAKKER, N G, LANGE, J M A, ...

In 219 HIV-1-infected men of the Amsterdam cohort we measured CD4+ T cell numbers and in vitro T cell responses to CD3 MoAbs with or without CD28 costimulation and phytohaemagglutinin (PHA). The...