Type III secretion à la Chlamydia (2007)
Peters, J., Wilson, David Peter Murray, Myers, G., Timms, P., Bavoil, P.M.
Jan Peters, David P. Wilson, Garry Myers, Peter Timms and Patrik M. Bavoil
Type III secretion à la Chlamydia (2007)
Peters, J., Wilson, David Peter Murray, Myers, G., Timms, P., Bavoil, P.M.
Jan Peters, David P. Wilson, Garry Myers, Peter Timms and Patrik M. Bavoil
Anti-P-gingivalis response correlates with atherosclerosis (2007)
Ford, PJ, Gemmell, E, Timms, P, Chan, A, Preston, FM, Seymour, GJ
Significant associations between atherosclerosis and both Porphyromonas gingivalis, a major periodontopathogen, and the respiratory pathogen, Chlamydia pneumoniae, have been shown. Many individuals...
Kumar, S, Kutlin, A, Roblin, P, Kohlhoff, S, Bodetti, T, Timms, P, ...
A range of species of Chlamydiales have previously been detected in a variety of Australian marsupials, including koalas and western barred bandicoots. Thirty-seven ocular, urogenital, or nasal swabs...
Anti-P. gingivalis response correlates with atherosclerosis (2007)
Ford, P. J., Gemmell, E., Timms, P., Chan, A., Preston, F. M., Seymour, G. J.
Significant associations between atherosclerosis and both Porphyromonas gingivalis, a major periodontopathogen, and the respiratory pathogen, Chlamydia pneumoniae, have been shown. Many individuals...
Anti-P. gingivalis response correlates with atherosclerosis (2007)
Ford, P. J., Gemmell, E., Timms, P., Chan, A., Preston, F. M., Seymour, G. J.
Significant associations between atherosclerosis and both Porphyromonas gingivalis, a major periodontopathogen, and the respiratory pathogen, Chlamydia pneumoniae, have been shown. Many individuals...
Tissue MicroArray (TMA) analysis of normal and persistent Chlamydophila pneumoniae infection. (2006)
Borel, N, Mukhopadhyay, S, Kaiser, C, Sullivan, E D, Miller, R D, Timms, P, ...
BACKGROUND: Chlamydophila pneumoniae infection has been implicated as a potential risk factor for atherosclerosis, however the mechanism leading to persistent infection and its role in the disease...
Mukhopadhyay, S, Good, D, Miller, RD, Graham, JE, Mathews, SA, Timms, P, ...
dChlamydia pneumoniae is an important human respiratory pathogen that is responsible for an estimated 10% of community-acquired pneumonia and 5% of bronchitis and sinusitis cases. We examined changes...
Mukhopadhyay, S., Good, D., Miller, R. D., Graham, J. E., Mathews, S. A., Timms, P., ...
dChlamydia pneumoniae is an important human respiratory pathogen that is responsible for an estimated 10% of community-acquired pneumonia and 5% of bronchitis and sinusitis cases. We examined changes...
Improved prediction of bacterial transcription start sites (2006)
Gordon, J. J., Towsey, M. W., Hogan, J. M., Mathews, S. A., Timms, P.
Motivation: Identifying bacterial promoters is an important step towards understanding gene regulation. In this paper, we address the problem of predicting the location of promoters and their...
Koalas at risk: From retroviruses to chlamydia (2005)
Tarlinton, R. E., Simmons, G. S., Phillips, C., Hanger, J., Timms, P., ...
Cochrane, M., Pospischil, A., Walker, P., Gibbs, H., Timms, P.
Aim: To determine the presence of Chlamydia pneumoniae in carotid plaque and peripheral blood mononuclear cells (PBMCs) using a combination of serology, direct antigen detection by immunofluorescence...
Multiple genotypes of Chlamydia pneumoniae identified in human carotid plaque (2005)
Cochrane, M, Walker, P, Gibbs, H, Timms, P
Chlamydia pneumoniae is an obligate intracellular respiratory pathogen that causes 10% of community-acquired pneumonia and has been associated with cardiovascular disease. Both whole-genome...
Cochrane, M., Pospischil, A., Walker, P., Gibbs, H., Timms, P.
Aim: To determine the presence of Chlamydia pneumoniae in carotid plaque and peripheral blood mononuclear cells (PBMCs) using a combination of serology, direct antigen detection by immunofluorescence...
Multiple genotypes of Chlamydia pneumoniae identified in human carotid plaque (2005)
Cochrane, M, Walker, P, Gibbs, H, Timms, P
Chlamydia pneumoniae is an obligate intracellular respiratory pathogen that causes 10% of community-acquired pneumonia and has been associated with cardiovascular disease. Both whole-genome...
Koalas at risk: From retroviruses to chlamydia (2005)
Tarlinton, R. E., Simmons, G. S., Phillips, C., Hanger, J., Timms, P., ...
Improved prediction of bacterial transcription start sites (2005)
Gordon, J. J., Towsey, M. W., Hogan, J. M., Mathews, S. A., Timms, P.
Motivation: Identifying bacterial promoters is an important step toward understanding gene regulation. In this paper, we address the problem of predicting the location of promoters and their...
Cochrane, M., Pospischil, A., Walker, P., Gibbs, H., Timms, P.
Despite extensive efforts to confirm a direct association between Chlamydia pneumoniae and atherosclerosis, different laboratories continue to report a large variability in detection rates. In this...
Bodetti, T. J., Hengstberger, K., Johnston, S., Timms, P.
Semen from seven koalas was extended in a tris-citrate glucose diluent containing one of four antibiotics at different concentrations and then contaminated with a standard concentration of...
Cochrane, M., Pospischil, A., Walker, P., Gibbs, H., Timms, P.
Despite extensive efforts to confirm a direct association between Chlamydia pneumoniae and atherosclerosis, different laboratories continue to report a large variability in detection rates. In this...
Bodetti, T. J., Hengstberger, K., Johnston, S., Timms, P.
Semen from seven koalas was extended in a tris-citrate glucose diluent containing one of four antibiotics at different concentrations and then contaminated with a standard concentration of...
Novel PCR-EIA method for the detection of Chlamydia pneumoniae in respiratory specimens (2002)
Inman-Bamber, J, Wan, C, Gardam, T, Vohra, R, Van Daal, A, Timms, P
We report the development of a microtitre plate-based PCR-EIA assay (ELAHA; Enzyme Linked Amplification and Hybridization Assay) for the sensitive and specific detection of Chlamydia pneumoniae in...
Novel PCR-EIA method for the detection of Chlamydia pneumoniae in respiratory specimens (2002)
Inman-Bamber, J, Wan, C, Gardam, T, Vohra, R, Van Daal, A, Timms, P
We report the development of a microtitre plate-based PCR-EIA assay (ELAHA; Enzyme Linked Amplification and Hybridization Assay) for the sensitive and specific detection of Chlamydia pneumoniae in...
Novel PCR-EIA method for the detection of Chlamydia pneumoniae in respiratory specimens (2002)
Inman-Bamber, J, Wan, C, Gardam, T, Vohra, R, Van Daal, A, Timms, P
We report the development of a microtitre plate-based PCR-EIA assay (ELAHA; Enzyme Linked Amplification and Hybridization Assay) for the sensitive and specific detection of Chlamydia pneumoniae in...
PCR detection of Chlamydia in koala (Phascolarctos cinereus) semen (2002)
Bodetti, T., Johnston, S. D., Pospischil, A, Knox, C, Timms, P.
Screening semen from koalas (Phascolarctos cinereus) for Chlamydia species by PCR (2002)
Bodetti, T. J., Johnston, S., Pospischil, A., Knox, C., Timms, P.
Artificial insemination is a valuable method for facilitating genetic exchange between captive colonies of koalas (Phascolarctos cinereus) and for the maintenance of genetically important remnant...
Novel PCR-EIA method for the detection of Chlamydia pneumoniae in respiratory specimens (2002)
Inman-Bamber, J, Wan, C, Gardam, T, Vohra, R, Van Daal, A, Timms, P
We report the development of a microtitre plate-based PCR-EIA assay (ELAHA; Enzyme Linked Amplification and Hybridization Assay) for the sensitive and specific detection of Chlamydia pneumoniae in...
PCR detection of Chlamydia in koala (Phascolarctos cinereus) semen (2002)
Bodetti, T., Johnston, S. D., Pospischil, A, Knox, C, Timms, P.
Screening semen from koalas (Phascolarctos cinereus) for Chlamydia species by PCR (2002)
Bodetti, T. J., Johnston, S., Pospischil, A., Knox, C., Timms, P.
Artificial insemination is a valuable method for facilitating genetic exchange between captive colonies of koalas (Phascolarctos cinereus) and for the maintenance of genetically important remnant...
Radical changes to chlamydial taxonomy are not necessary just yet (letter and reply) (2001)
Schachter, J., Stephens, R.S., Timms, P., Kuo, C., Bavoil, P.M., Birkelund, S., ...
Development of ligase-assisted spacer addition for the measurement of microsatellites (2001)
Brockhurst, V., Barnard, R., Wolter, L., Giffard, P., Timms, P.
Conventional methods for detecting differences in microsatellite repeat lengths rely on electrophoretic fractionation on long denaturing polyacrylamide gels, a time-consuming and labor-intensive...
Development of ligase-assisted spacer addition for the measurement of microsatellites (2001)
Brockhurst, V., Barnard, R., Wolter, L., Giffard, P., Timms, P.
Conventional methods for detecting differences in microsatellite repeat lengths rely on electrophoretic fractionation on long denaturing polyacrylamide gels, a time-consuming and labor-intensive...
Project FATIMA Final Report: Part 2 (1999)
May, A.D., Marler, N., Shepherd, S., Timms, P.
The final report of project FATIMA is presented in two parts. Part 1 contains a summary of the FATIMA method and sets out the key recommendations in terms of policies and optimisation methodology...
Project FATIMA Final Report: Part 1. (1999)
May, A.D., Marler, N., Shepherd, S., Timms, P.
EXECUTIVE SUMMARY This Final Report covers the results of the EU-funded research project FATIMA (Financial Assistance for Transport Integration in Metropolitan Areas) which had the following...
Project FATIMA Final Report: Part 2 (1999)
May, A.D., Marler, N., Shepherd, S., Timms, P.
The final report of project FATIMA is presented in two parts. Part 1 contains a summary of the FATIMA method and sets out the key recommendations in terms of policies and optimisation methodology...
Project FATIMA Final Report: Part 1. (1999)
May, A.D., Marler, N., Shepherd, S., Timms, P.
EXECUTIVE SUMMARY This Final Report covers the results of the EU-funded research project FATIMA (Financial Assistance for Transport Integration in Metropolitan Areas) which had the following...
Project FATIMA Final Report: Part 2 (1999)
May, A.D., Marler, N., Shepherd, S., Timms, P.
The final report of project FATIMA is presented in two parts. Part 1 contains a summary of the FATIMA method and sets out the key recommendations in terms of policies and optimisation methodology...
Project FATIMA Final Report: Part 1. (1999)
May, A.D., Marler, N., Shepherd, S., Timms, P.
EXECUTIVE SUMMARY This Final Report covers the results of the EU-funded research project FATIMA (Financial Assistance for Transport Integration in Metropolitan Areas) which had the following...
Identification of current practice and future opportunities in private financing (1998)
Marler, N., Estlander, Katja, May, A., Himanen, Veli, Timms, P., Järvi-Nykänen, Tuuli
8th World Conference of Transport Research, Antwerpen, July 1998
The overall objectives of Project OPTIMA are:- (i) to identify optimal urban transport strategies for a range of urban areas within the EU; (ii) to compare the strategies which are specified as...
The overall objectives of Project OPTIMA are:- (i) to identify optimal urban transport strategies for a range of urban areas within the EU; (ii) to compare the strategies which are specified as...
The overall objectives of Project OPTIMA are:- (i) to identify optimal urban transport strategies for a range of urban areas within the EU; (ii) to compare the strategies which are specified as...
PROJECT OPTIMA: optimisation of policies for transport integration in metropolitan areas (1997)
May, A.D., Shepherd, S., Timms, P.
The overall objectives of Project OPTIMA were: (i) to identify optimal urban transport and land use strategies for a range of urban areas within the EU; (ii) to compare the strategies which are...
PROJECT OPTIMA: optimisation of policies for transport integration in metropolitan areas (1997)
May, A.D., Shepherd, S., Timms, P.
The overall objectives of Project OPTIMA were: (i) to identify optimal urban transport and land use strategies for a range of urban areas within the EU; (ii) to compare the strategies which are...
PROJECT OPTIMA: optimisation of policies for transport integration in metropolitan areas (1997)
May, A.D., Shepherd, S., Timms, P.
The overall objectives of Project OPTIMA were: (i) to identify optimal urban transport and land use strategies for a range of urban areas within the EU; (ii) to compare the strategies which are...
Implementation of Pedestrian Meso Models in Portugal. VRU-TOO Deliverable 8. (1994)
DRIVE I Project "An Intelligent Traffic System for Vulnerable Road Users" created a computer model WLCAN1, which simulated the crossing behaviour of pedestrians on a length of urban street....
Implementation of Pedestrian Meso Models in Portugal. VRU-TOO Deliverable 8. (1994)
DRIVE I Project "An Intelligent Traffic System for Vulnerable Road Users" created a computer model WLCAN1, which simulated the crossing behaviour of pedestrians on a length of urban street....
Implementation of Pedestrian Meso Models in Portugal. VRU-TOO Deliverable 8. (1994)
DRIVE I Project "An Intelligent Traffic System for Vulnerable Road Users" created a computer model WLCAN1, which simulated the crossing behaviour of pedestrians on a length of urban street....
The Pathogenesis of Hypochromic Anaemia in Saudi Infants (1989)
Stevens, D. W., Wainscoat, J. S., Ketley, N., Timms, P., Ayoub, D., Shah, R.
The pathogenesis of hypochromic anaemia was studied in 138 Saudi bedouin infants aged 9 months. Approximately 25 per cent had hypochromic anaemia, but less than 10 per cent had serum ferritin levels...
Cytotoxic-T-lymphocyte-mediated cytolysis of L cells persistently infected with Chlamydia spp.
Rasmussen, S J, Timms, P, Beatty, P R, Stephens, R S
Persistent chlamydial infections have been proposed as a means whereby chlamydiae evade immune resolution of infection. Such a mechanism would require evasion not only of the humoral immune responses...
Turner, M S, Timms, P, Hafner, L M, Giffard, P M
Extraction of Lactobacillus fermentum BR11 cells with 5 M LiCl yielded a preparation containing a single predominant polypeptide with an apparent molecular mass of 32 kDa. A clone encoding an...
Inhibition of Babesia spp. by plastics.
Five commercially available plastic containers were compared with glass for toxicity toward Babesia rodhaini and Babesia bigemina. Comparisons were made by using infectivity tests in mice (B....
Study of virulence and vector transmission of Babesia bovis by use of cloned parasite lines.
Timms, P, Stewart, N P, De Vos, A J
Cloned lines of Babesia bovis were prepared from the avirulent vaccine strain, Ka, by an in vivo limiting dilution procedure. The virulence of these clones for adult Bos taurus cattle varied from...
Comparison of Chlamydia psittaci isolates by restriction endonuclease and DNA probe analyses.
Timms, P, Eaves, F W, Girjes, A A, Lavin, M F
DNAs from eight Chlamydia psittaci isolates (koala conjunctivitis, avian psittacosis, avian ornithosis, ovine abortion, ovine polyarthritis, sporadic bovine encephalomyelitis, and feline...
Girjes, A A, Hugall, A F, Timms, P, Lavin, M F
While several diseases associated with Chlamydia psittaci infection have been reported in Phascolarctos cinereus (koala), it is still unclear whether one or more chlamydial strains are responsible....
Wagels, G, Rasmussen, S, Timms, P
The 60-kDa cysteine-rich outer membrane protein gene (omp 2) from nine Chlamydia pneumoniae isolates (TW-183, CM-1, CWL-050, CWL-011, IOL-207, FIL, Kajaani-6, Helsinki-12, and Parjaanonen) was...
Chlamydia psittaci is the major cause of infectious disease in the koala (Phascolarctos cinereus). It causes four disease syndromes in the koala, namely, conjunctivitis, rhinitis, cystitis, and...
Cytotoxic-T-lymphocyte-mediated cytolysis of L cells persistently infected with Chlamydia spp.
Rasmussen, S J, Timms, P, Beatty, P R, Stephens, R S
Persistent chlamydial infections have been proposed as a means whereby chlamydiae evade immune resolution of infection. Such a mechanism would require evasion not only of the humoral immune responses...
Turner, M S, Timms, P, Hafner, L M, Giffard, P M
Extraction of Lactobacillus fermentum BR11 cells with 5 M LiCl yielded a preparation containing a single predominant polypeptide with an apparent molecular mass of 32 kDa. A clone encoding an...
Inhibition of Babesia spp. by plastics.
Five commercially available plastic containers were compared with glass for toxicity toward Babesia rodhaini and Babesia bigemina. Comparisons were made by using infectivity tests in mice (B....
Study of virulence and vector transmission of Babesia bovis by use of cloned parasite lines.
Timms, P, Stewart, N P, De Vos, A J
Cloned lines of Babesia bovis were prepared from the avirulent vaccine strain, Ka, by an in vivo limiting dilution procedure. The virulence of these clones for adult Bos taurus cattle varied from...
Comparison of Chlamydia psittaci isolates by restriction endonuclease and DNA probe analyses.
Timms, P, Eaves, F W, Girjes, A A, Lavin, M F
DNAs from eight Chlamydia psittaci isolates (koala conjunctivitis, avian psittacosis, avian ornithosis, ovine abortion, ovine polyarthritis, sporadic bovine encephalomyelitis, and feline...
Girjes, A A, Hugall, A F, Timms, P, Lavin, M F
While several diseases associated with Chlamydia psittaci infection have been reported in Phascolarctos cinereus (koala), it is still unclear whether one or more chlamydial strains are responsible....
Wagels, G, Rasmussen, S, Timms, P
The 60-kDa cysteine-rich outer membrane protein gene (omp 2) from nine Chlamydia pneumoniae isolates (TW-183, CM-1, CWL-050, CWL-011, IOL-207, FIL, Kajaani-6, Helsinki-12, and Parjaanonen) was...
Chlamydia psittaci is the major cause of infectious disease in the koala (Phascolarctos cinereus). It causes four disease syndromes in the koala, namely, conjunctivitis, rhinitis, cystitis, and...
Development of ligase-assisted spacer addition for the measurement of microsatellites
Brockhurst, V, Barnard, R, Wolter, L, Giffard, P, Timms, P
Conventional methods for detecting differences in microsatellite repeat lengths rely on electrophoretic fractionation on long denaturing polyacrylamide gels, a time-consuming and labor-intensive...
Simmonds, H A, Fairbanks, L D, Morris, G S, Morgan, G, Watson, A R, Timms, P, ...
Developmental retardation was a prominent clinical feature in six infants from three kindreds deficient in the enzyme purine nucleoside phosphorylase (PNP) and was present before development of T...