Assessing a patient-centered e-health approach to chronic disease self-management (2008)
Cummings, EA, Chau, S, Turner, P
This chapter explores how in developing patient-centred e-health systems it is possible to accommodate heterogeneous characteristics of end-users and their diverse health and care contexts. It...
A model for simulating the deposition of water-lain sediments in dryland environments (2008)
Bunch, M. A., Mackay, R., Tellam, J. H., Turner, P.
A numerical process-imitating model, the Discrete Storm Event Sedimentation Simulator (DSESS), has been developed to represent the climatic and hydraulic conditions of drylands in modelling their...
Assessing a patient-centered e-health approach to chronic disease self-management (2008)
Cummings, EA, Chau, S, Turner, P
This chapter explores how in developing patient-centred e-health systems it is possible to accommodate heterogeneous characteristics of end-users and their diverse health and care contexts. It...
Nijnatten, P.A. Van, Hutchins, M.G., Kilbey, N.B., Roos, A., Gelin, K., Geotti-Bianchini, F., ...
The emissivity of coated glazing is commonly determined from spectral reflectance measurements using a specular reflectance accessory or other suitable reflectance attachment. As part of the ongoing...
Milsmann, C., Levina, A., Harris, Hugh Hamlyn, Foran, G J., Turner, P., Lay, P A.
Copyright © 2006 American Chemical Society
Milsmann, C., Levina, A., Harris, Hugh Hamlyn, Foran, G J., Turner, P., Lay, P A.
Copyright © 2006 American Chemical Society
Proposal of a kit-style robot as the new standard platform for the four-legged league (2006)
Chalup, S. K., Dickinson, M., Fisher, R., Middleton, R. H., Quinlan, M. J., Turner, P.
In 2006 the Sony Corporation announced that production of the Aibo robot, which is the standard robot platform of the four-legged league of RoboCup, would be discontinued. This paper describes a...
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The versatility of palladium(II) as a template for Mannich-type macrocyclization is illustrated. Reaction of (bis(3-aminopropyl)piperazine)palladium(II) with formaldehyde and nitroethane in basic...
Payne, S., Sheldon, F., Jarrett, N., Smith, P., Davis, C., Turner, P., ...
This paper describes a study that sought to identify service providers' and commissioners' understanding of specialist palliative care within the context of changing service provision in one area of...
Huntly, B.J.P., Reid, A.G., Bench, A.J., Campbell, L.J., Telford, N., Shepherd, P., ...
Chronic myeloid leukemia (CML) is characterized by formation of the BCR-ABL fusion gene, usually as a consequence of the Philadelphia (Ph) translocation between chromosomes 9 and 22. Large deletions...
Palliative care: A suitable setting for undergraduate interprofessional education (2001)
Wee, B., Hillier, R., Coles, C., Mountford, B., Sheldon, B., Turner, P.
Effective delivery of high-quality palliative care requires effective inter-professional teamworking by skilled health and social care professionals. Palliative care is therefore highly suitable for...
Turner, P., Dear, J., Scadding, G., Foreman, J.C.
Background: Icatibant, a bradykinin B2 receptor antagonist, inhibits the reduction in nasal patency after challenge with house dust mite antigen in sensitive subjects and abolishes the nasal...
Community Pharmacy Medication Incident and Reporting Management System (CPMIRMS) (PROMISe)
Peterson, GM, Tenni, PC, Hasan, O, Liauw, C, Reeve, J, Turner, P, ...
The fate of the below knee amputee.
De Cossart, L., Randall, P., Turner, P., Marcuson, R. W.
A retrospective study of 47 patients undergoing 51 below-knee amputations over a six year period on one unit is reported. An overall success rate of 84.4% was achieved and the factors influencing...
Views of hospital staff on the management of hypertension.
Hutchinson, P. J., Trill, A. S., Turner, P., Jackson, S. H.
A questionnaire concerning the detection and management of hypertension was presented to 265 hospital doctors, 114 medical students and 59 student nurses. Of these 75% were completed. Although only...
Farthing, M. J., Alstead, E. M., Abrams, S. M., Haug, G., Johnston, A., Hermann, R., ...
The pharmacokinetics of naftopidil, a novel alpha-1 adrenoceptor-blocking antihypertensive, were investigated in ten patients (9M/1F) with hepatic dysfunction after oral administration (50 mg,...
Al-Sereiti, M. R., Turner, P., Gale, E. A.
The effect of bromocriptine on intraocular pressure has been investigated in a group of 8 diabetic patients with autonomic neuropathy, to test the hypothesis that bromocriptine exerts its ocular...
Intraocular pressure and pupillary responses in patients with diabetes mellitus.
Al-Sereiti, M. R., Turner, P., Gale, E. A.
Intraocular pressure (IOP) and the mydriatic responses to darkness in 38 diabetic patients have been compared with those of a matched control group of normal subjects. Overall, the diabetic patients...
Interaction of ketoprofen and frusemide in man.
Wa, T. C., Lawson, M., Jackson, S. H., Hitoglou-Makedou, A., Turner, P.
The effects of ketoprofen on frusemide-induced diuresis, natriuresis and renin release were studied in 12 healthy male volunteers. Each received frusemide 40 mg once daily with either ketoprofen 100...
Li Kam Wa, T. C., Cooke, E. D., Beacham, J., Turner, P.
A double-blind, randomized, cross-over, placebo-controlled study was carried out to determine the extent and duration of potentiation of the action of bradykinin introduced intradermally by a...
A pharmacokinetic interaction between cimetidine or ranitidine and lornoxicam.
Ravic, M., Salas-Herrera, I., Johnston, A., Turner, P., Foley, K., Rosenow, D. E.
Cimetidine 400 mg twice daily significantly increased serum concentrations and reduced apparent oral clearance of lornoxicam 8 mg twice daily in 12 healthy volunteers. Ranitidine 150 mg twice daily...
The pharmacokinetics of lysine theophylline, a new soluble theophylline, in human volunteers.
Johnston, A., Aldhous, M. E., Hedges, A., Weerasuriya, K., Freedman, A., Turner, P.
A comparative study of the pharmacokinetics of lysine theophylline and aminophylline in normal subjects reveals no significant difference. If lysine theophylline is shown to have the same clinical...
Kovacs, I. B., Dowd, P. M., Kirby, J. D., Turner, P.
Basal intracellular cAMP levels of lymphocytes from patients with systemic sclerosis, all suffering from Raynaud's phenomenon, were significantly lower than those obtained from normal controls....
Measurement of systolic time intervals is a valuable, non-invasive procedure to assess left ventricular performance, particularly when influenced by drugs. In this review, we discuss various factors...
Kilfeather, S. A., Massarella, A., Gorgolewska, G., Ansell, E., Turner, P.
Beta-adrenoceptor blocking drugs are of prophylactic value in some patients with migraine. Beta-adrenoceptor responsiveness as measured by lymphocyte cAMP responsiveness to isoprenaline has,...
Muhiddin, K. A., Turner, P., Hellestrand, K., Camm, A. J.
The efficacy of flecainide acetate in suppressing ventricular premature contractions in 14 patients was evaluated in a double-blind, cross-over, placebo controlled, randomized and balanced study....
Propranolol pharmacokinetics during the menstrual cycle.
Abdu-Aguye, I., Dunlop, D., Patel, P., Turner, P.
The pharmacokinetics of propranolol during menstruation and in the mid menstrual cycle have been studied in nine young women taking a single 80 mg tablet on each occasion. There were wide...
Anti-hypertensive therapy with propranolol during pregnancy and lactation.
A hypertensive women was treated throughout pregnancy with propranolol 40 mg daily without complication. At delivery the umbilical cord plasma concentration was similar to that in the maternal venous...
Anticholinergic drugs, buccal ulceration and mucosal potential difference.
Huston, G. J., Abrams, S. M., Turner, P.
Measurement of changes in buccal mucosal potential difference produced by contact with drug formulations may provide a means of predicting their mucosal toxicity and ulcerogenic activity.
Salivary theophylline estimation in the management of asthma in children.
Lena, S. M., Hutchins, P., Wood, C. B., Turner, P.
Simultaneous sampling was performed to determine whether saliva could replace plasma in the monitoring of theophylline dosages. Forty-eight children with moderate to severe asthma received oral...
Burgess, C. D., Montgomery, S., Wadsworth, J., Turner, P.
The cardiac effects of amitriptyline, mianserin, zimelidine and nomifensine on the systolic time intervals (STI) and on the high speed surface ECG have been studied in depressed patients....
Henry, J., Turner, P., Garland, M., Esmieu, F.
In a 6-volunteer cross-over study the pharmacokinetics of 3 erythromycin preparations were compared. A single oral dose of 500 mg of each preparation was administered at each occasion and the levels...
Platelet monoamine uptake in relatives of patients with Huntington's chorea.
Uptake of dopamine and 5-hydroxytryptamine (5-HT) by the platelets of 25 symptom-free relatives of patients with established Huntington's chorea (HC) was not significantly different from that of...
Mexiletine in human blood and breast milk.
Lewis, A. M., Patel, L., Johnston, A., Turner, P.
Twelve paired samples of breast milk and blood were obtained, between the 2nd and 5th days after she had given birth, from a 30-year-old woman who was a 8-hourly propranolol (20 mg) and mexiletine...
A comparison of antrafenine and aspirin on platelet aggregation and frusemide-induced diuresis.
Hassan, S. M., Olivesi, A., Fish, A., Turner, P.
The effects of antrafenine were compared with aspirin and placebo on platelet aggregation and on the diuretic action of frusemide in normal volunteers. Aspirin significantly reduced platelet...
Pharmacokinetics of flupirtine in elderly volunteers and in patients with moderate renal impairment.
Abrams, S. M., Baker, L. R., Crome, P., White, A. S., Johnston, A., Ankier, S. I., ...
The pharmacokinetics of flupirtine after a single oral dose of 100mg have been studied in patients with moderate renal impairment and in healthy elderly subjects aged 66-83 years. Mean elimination...
Comparison of flupirtine and indomethacin on frusemide-induced diuresis.
Johnston, A., Warrington, S. J., Turner, P., Riethmuller-Winzen, H.
A single oral dose of flupirtine maleate, a novel analgesic agent, did not antagonize significantly the diuretic action of frusemide when compared with indomethacin and placebo in normal human...
Recent observations on drugs and human fertility.
The transmembrane migration method has permitted quantification of the effect of drugs on human sperm motility. Calcium ionophores and calcium antagonists have paradoxical effects on motility...
Chlortenoxicam pharmacokinetics in young and elderly human volunteers.
Ankier, S. I., Brimelow, A. E., Crome, P., Johnston, A., Warrington, S. J., Turner, P., ...
The pharmacokinetics of chlortenoxicam, a new non-steroidal anti-inflammatory drug, have been compared in young and elderly healthy human volunteers. Chlortenoxicam was found to have a relatively...
Comparison of chlortenoxicam and indomethacin on frusemide-induced diuresis.
Hitoglou-Makedou, A., Lawson, M., Turner, P., Ferber, H. P.
A single oral dose of chlortenoxicam 4 mg, a new non-steroidal anti-inflammatory drug, significantly antagonized the diuretic and natriuretic actions of frusemide when compared with placebo in normal...
Warrington, S. J., Debbas, N. M., Farthing, M., Horton, M., Johnston, A., Thillainayagam, A., ...
Forty-five healthy men aged 21-34 years took part in a double-blind, parallel-group, placebo-controlled study of the effects of 28 days' treatment with lornoxicam 4 mg twice daily or indomethacin 50...
Comparison of propranolol and LB 46 (prinodolol) on hyperthyroid tachycardia
LB 46 (prinodolol) a β-adrenergic receptor blocking drug which is more potent than propranolol in euthyroid subjects, is less effective in inhibiting hyperthyroid tachycardia. This is probably due...
Differences in formulation are of greater clinical importance in the case of sparingly soluble drugs, those with small therapeutic doses, in replacement therapy and in the control of serious clinical...
In the treatment of fifteen patients with essential hypertension, in open trial indoramin caused a mean blood pressure fall from 180/115 mmHg to 159/98 mmHg. No reversal of antihypertensive effect...
5-Hydroxytryptamine (5-HT) in the whole-blood of patients with depressive illness
Coppen, A., Rowsell, A. R., Turner, P., Padgham, Cheryl
Whole-blood 5-HT was examined in thirty-five depressive patients not on antidepressants, and in comparable control subjects. The concentration of whole-blood 5-HT was significantly lower during...