P. Ulrich

Publication List Details

Period

2003 - 2007

Number

12

Co-Authors

An European inter-laboratory validation of alternative endpoints of the murine local lymph node assay: First round (2005)

Ehling, G., Hecht, M., Heusener, A., Huesler, J., Gamer, A., Loveren, H. Van, ...

The new OECD guideline 429 (skin sensitization: local lymph node assay) is based upon a protocol, which utilises the incorporation of radioactivity into DNA as a measure for cell proliferation in...

An European inter-laboratory validation of alternative endpoints of the murine local lymph node assay 2nd round (2005)

Ehling, G., Hecht, M., Heusener, A., Huesler, J., Gamer, A., Loveren, H. Van, ...

The original local lymph node assay (LLNA) is based on the use of radioactive labelling to measure cell proliferation. Other endpoints for the assessment of proliferation are also authorized by the...

Mars Together 2001: Joint US-Russian Team (2004)

Ulrich, P., Kremnev, R., Boyce, J., Eremenko, A., Bourke, R., Linkin, V., ...

While the US and USSR have collaborated in human space flight and Earth application missions, this is the first time in the cultural relations between our two countries that American and Russian...

Critical role of reverse transcriptase in the inhibitory mechanism of CNI-H0294 on HIV-1 nuclear translocation.

Popov, S, Dubrovsky, L, Lee, M A, Pennathur, S, Haffar, O, AL-Abed, Y, ...

HIV-1 replication requires the translocation of viral genome into the nucleus of a target cell. We recently reported the synthesis of an arylene bis(methyl ketone) compound (CNI-H0294) that inhibits...

"Subversive" substrates for the enzyme trypanothione disulfide reductase: alternative approach to chemotherapy of Chagas disease.

Henderson, G B, Ulrich, P, Fairlamb, A H, Rosenberg, I, Pereira, M, Sela, M, ...

The trypanosomatid flavoprotein disulfide reductase, trypanothione reductase, is shown to catalyze one-electron reduction of suitably substituted naphthoquinone and nitrofuran derivatives. A number...

Critical role of reverse transcriptase in the inhibitory mechanism of CNI-H0294 on HIV-1 nuclear translocation.

Popov, S, Dubrovsky, L, Lee, M A, Pennathur, S, Haffar, O, AL-Abed, Y, ...

HIV-1 replication requires the translocation of viral genome into the nucleus of a target cell. We recently reported the synthesis of an arylene bis(methyl ketone) compound (CNI-H0294) that inhibits...

"Subversive" substrates for the enzyme trypanothione disulfide reductase: alternative approach to chemotherapy of Chagas disease.

Henderson, G B, Ulrich, P, Fairlamb, A H, Rosenberg, I, Pereira, M, Sela, M, ...

The trypanosomatid flavoprotein disulfide reductase, trypanothione reductase, is shown to catalyze one-electron reduction of suitably substituted naphthoquinone and nitrofuran derivatives. A number...

An inhibitor of macrophage arginine transport and nitric oxide production (CNI-1493) prevents acute inflammation and endotoxin lethality.

Bianchi, M., Ulrich, P., Bloom, O., Meistrell, M., Zimmerman, G. A., Schmidtmayerova, H., ...

BACKGROUND: Nitric oxide (NO), a small effector molecule produced enzymatically from L-arginine by nitric oxide synthase (NOS), is a mediator not only of important homeostatic mechanisms (e.g., blood...

Nuclear localization signal of HIV-1 as a novel target for therapeutic intervention.

Dubrovsky, L., Ulrich, P., Nuovo, G. J., Manogue, K. R., Cerami, A., Bukrinsky, M.

BACKGROUND: Human immunodeficiency virus type 1 (HIV-1) is a lentivirus and shares with other members of this retroviral subfamily the ability to replicate in nondividing cells, in particular, cells...

Occupational risk factors for symptomatic lumbar disc herniation; a case-control study

Seidler, A, Bolm-Audorff, U, Siol, T, Henkel, N, Fuchs, C, Schug, H, ...

Background: Previous studies mostly did not separate between symptomatic disc herniation combined with osteochondrosis/spondylosis of the lumbar spine and symptomatic disc herniation in...