Barbry, P, Chassande, O, Vigne, P, Frelin, C, Ellory, C, Cragoe, E J, ...
Sodium crosses the apical membrane of tight epithelia through a sodium channel, which is inhibited by the diuretic amiloride and by analogs such as phenamil. Target size analysis indicated that the...
Vigne, P, Frelin, C, Lazdunski, M
The internal pH (pHi) of chick muscle cells is determined by the transmembrane Na+ gradient. Li+, but not K+, Rb+ or Cs+, can substitute for Na+ for regulating the internal pH of chick muscle cells....
Vigne, P, Frelin, C, Audinot, M, Borsotto, M, Cragoe, E J, Lazdunski, M
The interaction of amiloride and several amiloride derivatives with the Na+/H+ exchange system in Madin-Darby canine kidney cells and in rabbit renal microvillus membrane vesicles was studied from...
Vigne, P, Marsault, R, Breittmayer, J P, Frelin, C
Endothelin-1 (ET-1) is a novel vasoconstricting and cardiotonic peptide that is synthesized by the vascular endothelium. Bovine aortic endothelial cells which secrete ET in vitro lack membrane...
Barbry, P, Chassande, O, Vigne, P, Frelin, C, Ellory, C, Cragoe, E J, ...
Sodium crosses the apical membrane of tight epithelia through a sodium channel, which is inhibited by the diuretic amiloride and by analogs such as phenamil. Target size analysis indicated that the...
Vigne, P, Frelin, C, Lazdunski, M
The internal pH (pHi) of chick muscle cells is determined by the transmembrane Na+ gradient. Li+, but not K+, Rb+ or Cs+, can substitute for Na+ for regulating the internal pH of chick muscle cells....
Vigne, P, Frelin, C, Audinot, M, Borsotto, M, Cragoe, E J, Lazdunski, M
The interaction of amiloride and several amiloride derivatives with the Na+/H+ exchange system in Madin-Darby canine kidney cells and in rabbit renal microvillus membrane vesicles was studied from...
Vigne, P, Marsault, R, Breittmayer, J P, Frelin, C
Endothelin-1 (ET-1) is a novel vasoconstricting and cardiotonic peptide that is synthesized by the vascular endothelium. Bovine aortic endothelial cells which secrete ET in vitro lack membrane...
Sensitization by calyculin A of brain capillary endothelial cells to endothelin-1.
Vigne, P, Breittmayer, J P, Frelin, C
1. Cultured brain capillary endothelial cells of the rat respond to endothelin-1 (ET-1) by an increased activity of the Na+,K+,2Cl-, cotransporter and a mobilization of intracellular Ca2+ stores. 2....
Simon, J, Vigne, P, Eklund, K M, Michel, A D, Carruthers, A M, Humphrey, P P A, ...
A P2Y (nucleotide) receptor activity in a clonal population (B10) of rat brain capillary endothelial cells is coupled to inhibition of adenylyl cyclase and has functional similarities to the P2YT...
ATP, a partial agonist of atypical P2Y purinoceptors in rat brain microvascular endothelial cells.
Feolde, E., Vigne, P., Breittmayer, J. P., Frelin, C.
1. Purinoceptor responses were analyzed in B10 cells, a clonal population of rat brain capillary endothelial cells. 2. B10 cells lack P2U receptors as evidenced by the lack of UTP responses and the...
Vigne, P., Feolde, E., Breittmayer, J. P., Frelin, C.
1. Brain capillary endothelial cells responded to 2-methylthio-ATP (2MeSATP) by large increases in [Ca2+]i (EC50 = 27 nM) that were partially dependent on the presence of extracellular Ca2+ and that...
Webb, T. E., Feolde, E., Vigne, P., Neary, J. T., Runberg, A., Frelin, C., ...
1. B10 cells, a clonal line of rat brain capillary endothelial cells, exhibit a single P2 purinoceptor, activation of which leads to increases in free intracellular calcium. In the current study the...
Vigne, P., Pacaud, P., Urbach, V., Feolde, E., Breittmayer, J. P., Frelin, C.
1. Brain capillary endothelial cells responded to uridine 5'-triphosphate (UTP) and adenosine 5'-triphosphate (ATP) by activation of phospholipase C and by large changes in [Ca2+]i. These cells...