Effect of internal viral sequences on the utility of retroviral vectors.
Armentano, D, Yu, S F, Kantoff, P W, Von Ruden, T, Anderson, W F, Gilboa, E
Expression of the human ADA cDNA encoded by the Moloney murine leukemia virus spliced RNA form is enhanced by intron-contained sequences. The presence of sequences corresponding to the viral gag gene...
Garver, R I, Chytil, A, Karlsson, S, Fells, G A, Brantly, M L, Courtney, M, ...
Alpha 1-Antitrypsin (alpha 1AT) deficiency is a hereditary disorder characterized by reduced serum levels of alpha 1AT, resulting in destruction of the lower respiratory tract by neutrophil elastase....
Self-inactivating retroviral vectors designed for transfer of whole genes into mammalian cells.
Yu, S F, Von Rüden, T, Kantoff, P W, Garber, C, Seiberg, M, Rüther, U, ...
A retrovirus-derived vector called self-inactivating (SIN) vector was designed for the transduction of whole genes into mammalian cells. SIN vectors contain a deletion of 299 base pairs in the 3'...
Kantoff, P W, Kohn, D B, Mitsuya, H, Armentano, D, Sieberg, M, Zwiebel, J A, ...
A retroviral vector called SAX, containing the cloned human cDNA for adenosine deaminase (ADA), has been constructed and used to introduce the ADA gene into cultured T- and B-lymphocyte lines derived...
Modification of BRCA1-associated breast cancer risk by the polymorphic androgen-receptor CAG repeat.
Rebbeck, T R, Kantoff, P W, Krithivas, K, Neuhausen, S, Blackwood, M A, Godwin, A K, ...
Compared with the general population, women who have inherited a germline mutation in the BRCA1 gene have a greatly increased risk of developing breast cancer. However, there is also substantial...
Effect of internal viral sequences on the utility of retroviral vectors.
Armentano, D, Yu, S F, Kantoff, P W, Von Ruden, T, Anderson, W F, Gilboa, E
Expression of the human ADA cDNA encoded by the Moloney murine leukemia virus spliced RNA form is enhanced by intron-contained sequences. The presence of sequences corresponding to the viral gag gene...
Garver, R I, Chytil, A, Karlsson, S, Fells, G A, Brantly, M L, Courtney, M, ...
Alpha 1-Antitrypsin (alpha 1AT) deficiency is a hereditary disorder characterized by reduced serum levels of alpha 1AT, resulting in destruction of the lower respiratory tract by neutrophil elastase....
Self-inactivating retroviral vectors designed for transfer of whole genes into mammalian cells.
Yu, S F, Von Rüden, T, Kantoff, P W, Garber, C, Seiberg, M, Rüther, U, ...
A retrovirus-derived vector called self-inactivating (SIN) vector was designed for the transduction of whole genes into mammalian cells. SIN vectors contain a deletion of 299 base pairs in the 3'...
Kantoff, P W, Kohn, D B, Mitsuya, H, Armentano, D, Sieberg, M, Zwiebel, J A, ...
A retroviral vector called SAX, containing the cloned human cDNA for adenosine deaminase (ADA), has been constructed and used to introduce the ADA gene into cultured T- and B-lymphocyte lines derived...
Modification of BRCA1-associated breast cancer risk by the polymorphic androgen-receptor CAG repeat.
Rebbeck, T R, Kantoff, P W, Krithivas, K, Neuhausen, S, Blackwood, M A, Godwin, A K, ...
Compared with the general population, women who have inherited a germline mutation in the BRCA1 gene have a greatly increased risk of developing breast cancer. However, there is also substantial...