P. W. Roche

Publication List Details

Period

2006 - 2006

Number

11

Co-Authors

Tuberculosis notifications in Australia, 2004 (2006)

Roche, P. W., Bastian, Ivan, Brown, L. E., Christensen, A., Hurwitz, M., Konstantinous, A., ...

Paul W Roche1 and the National Tuberculosis Advisory Committee (Ral Antic – Chair, Ivan Bastian, Lynne Brown, Amanda Christensen, Mark Hurwitz, Anastasios Konstantinos, Vicki L Krause, Moira...

Tuberculosis notifications in Australia, 2004 (2006)

Roche, P. W., Bastian, Ivan, Brown, L. E., Christensen, A., Hurwitz, M., Konstantinous, A., ...

Paul W Roche1 and the National Tuberculosis Advisory Committee (Ral Antic – Chair, Ivan Bastian, Lynne Brown, Amanda Christensen, Mark Hurwitz, Anastasios Konstantinos, Vicki L Krause, Moira...

A 35-kilodalton protein is a major target of the human immune response to Mycobacterium leprae.

Triccas, J A, Roche, P W, Winter, N, Feng, C G, Butlin, C R, Britton, W J

The control of leprosy will be facilitated by the identification of major Mycobacterium leprae-specific antigens which mirror the immune response to the organism across the leprosy spectrum. We have...

Analysis of B-cell epitopes in the variable C-terminal region of the Mycobacterium leprae 70-kilodalton heat shock protein.

Peake, P W, Britton, W J, Davenport, M P, Roche, P W, McKenzie, K R

The C-terminal region of the Mycobacterium leprae 70-kDa heat-shock protein is the major target for the humoral immune response to this protein and contains M. leprae-specific sequences. To examine...

T-cell determinants and antibody binding sites on the major mycobacterial secretory protein MPB59 of Mycobacterium bovis.

Roche, P W, Peake, P W, Billman-Jacobe, H, Doran, T, Britton, W J

Among the first proteins encountered by the host immune system upon infection or vaccination with mycobacteria are those secreted by the bacillus during growth. The antigen 85 complex of...

A 35-kilodalton protein is a major target of the human immune response to Mycobacterium leprae.

Triccas, J A, Roche, P W, Winter, N, Feng, C G, Butlin, C R, Britton, W J

The control of leprosy will be facilitated by the identification of major Mycobacterium leprae-specific antigens which mirror the immune response to the organism across the leprosy spectrum. We have...

Analysis of B-cell epitopes in the variable C-terminal region of the Mycobacterium leprae 70-kilodalton heat shock protein.

Peake, P W, Britton, W J, Davenport, M P, Roche, P W, McKenzie, K R

The C-terminal region of the Mycobacterium leprae 70-kDa heat-shock protein is the major target for the humoral immune response to this protein and contains M. leprae-specific sequences. To examine...

T-cell determinants and antibody binding sites on the major mycobacterial secretory protein MPB59 of Mycobacterium bovis.

Roche, P W, Peake, P W, Billman-Jacobe, H, Doran, T, Britton, W J

Among the first proteins encountered by the host immune system upon infection or vaccination with mycobacteria are those secreted by the bacillus during growth. The antigen 85 complex of...

Cellular immune response to the cell walls of Mycobacterium leprae in leprosy patients and healthy subjects exposed to leprosy.

Roche, P W, Neupane, K D, Britton, W J

Cell walls of M. leprae consist of complex arrangements of carbohydrate, lipid, peptidoglycan and protein molecules. Recently, extractable proteins of a wide range of molecular weights were...

High levels of inflammatory cytokines are associated with poor clinical response to steroid treatment and recurrent episodes of type 1 reactions in leprosy

MANANDHAR, R, SHRESTHA, N, BUTLIN, C R, ROCHE, P W

Levels of leprosy antigen-induced interferon-gamma (IFN-γ), tumour necrosis factor alpha (TNF-α) and interleukin-10 (IL-10) were measured in 96 leprosy patients with type 1 reactions (T1R) before,...

Expression of Mycobacterium tuberculosis MPT64 in recombinant Myco. smegmatis: purification, immunogenicity and application to skin tests for tuberculosis

ROCHE, P W, WINTER, N, TRICCAS, J A, FENG, C G, BRITTON, W J

Proteins secreted across the cell wall of mycobacteria are important antigens recognized early in the host response to mycobacterial infection. MPT64 is a 23-kD secreted protein restricted to members...