Phenoxodiol, an experimental anticancer drug, shows potent antiangiogenic properties in addition to its antitumour effects (2006)
Gamble, J. R.,
Xia, P.,
Hahn, C. N.,
Drew, J. J.,
Drogemuller, C. J.,
Brown, D.,
...
Estrogen transactivates EGFR via the sphingosine 1-phosphate receptor Edg-3: the role of sphingosine kinase-1 (2006)
Sukocheva, O.,
Wadham, C.,
Holmes, A.,
Albanese, N.,
Verrier, E.,
Feng, F.,
...
Estrogen transactivates EGFR via the sphingosine 1-phosphate receptor Edg-3: the role of sphingosine kinase-1 (2006)
Sukocheva, O.,
Wadham, C.,
Holmes, A.,
Albanese, N.,
Verrier, E.,
Feng, F.,
...
Phenoxodiol, an experimental anticancer drug, shows potent antiangiogenic properties in addition to its antitumour effects (2006)
Gamble, J. R.,
Xia, P.,
Hahn, C. N.,
Drew, J. J.,
Drogemuller, C. J.,
Brown, D.,
...
Estrogen transactivates EGFR via the sphingosine 1-phosphate receptor Edg-3: the role of sphingosine kinase-1 (2006)
Sukocheva, O.,
Wadham, C.,
Holmes, A.,
Albanese, N.,
Verrier, E.,
Feng, F.,
...
Sphingosine kinase-1 enhances endothelial cell survival through a PECAM-1-dependent activation of PI-3K/Akt and regulation of Bcl-2 family members (2005)
Limaye, V. S.,
Li, X.,
Hahn, C. N.,
Xia, P.,
Berndt, M. C.,
Vadas, M.,
...
Activation of the sphingosine kinase-signaling pathway by high glucose mediates the proinflammatory phenotype of endothelial cells (2005)
Wang, L.,
Xing, X-P.,
Holmes, A. S.,
Wadham, C.,
Gamble, J. R.,
Vadas, M.,
...
Phosphorylation-dependent translocation of sphingosine kinase to the plasma membrane drives its oncogenic signalling (2005)
Pitson, Stuart Maxwell,
Xia, P.,
Leclercq, Tamara,
Moretti, P. A. B.,
Zebol, J. R.,
Lynn, H. E.,
...
Sphingosine kinase-1 enhances endothelial cell survival through a PECAM-1-dependent activation of PI-3K/Akt and regulation of Bcl-2 family members (2005)
Limaye, V. S.,
Li, X.,
Hahn, C. N.,
Xia, P.,
Berndt, M. C.,
Vadas, M.,
...
Activation of the sphingosine kinase-signaling pathway by high glucose mediates the proinflammatory phenotype of endothelial cells (2005)
Wang, L.,
Xing, X-P.,
Holmes, A. S.,
Wadham, C.,
Gamble, J. R.,
Vadas, M.,
...
Phosphorylation-dependent translocation of sphingosine kinase to the plasma membrane drives its oncogenic signalling (2005)
Pitson, Stuart Maxwell,
Xia, P.,
Leclercq, Tamara,
Moretti, P. A. B.,
Zebol, J. R.,
Lynn, H. E.,
...
High-density lipoproteins neutralize C-reactive protein proinflammatory activity (2004)
Wadham, C.,
Albanese, N. O.,
Roberts, J. L.,
Wang, L.,
Bagley, C. J.,
Gamble, J. R.,
...
PPARg agonists ameliorate endothelial cell activation via inhibition of diacylglycerol-protein kinase C signaling pathway - Role of diacylglycerol kinase (2004)
Verrier, E.,
Wang, L.,
Wadham, C.,
Albanese, N. O.,
Hahn, C. N.,
Gamble, J. R.,
...
High-density lipoproteins neutralize C-reactive protein proinflammatory activity (2004)
Wadham, C.,
Albanese, N. O.,
Roberts, J. L.,
Wang, L.,
Bagley, C. J.,
Gamble, J. R.,
...
PPARg agonists ameliorate endothelial cell activation via inhibition of diacylglycerol-protein kinase C signaling pathway - Role of diacylglycerol kinase (2004)
Verrier, E.,
Wang, L.,
Wadham, C.,
Albanese, N. O.,
Hahn, C. N.,
Gamble, J. R.,
...
Activation of sphingosine kinase 1 by ERK1/2-mediated phosphorylation (2003)
Pitson, S. M.,
Moretti, P. A.B.,
Zebol, J. R.,
Lynn, H. E.,
Xia, P.,
Vadas, M.,
...
Sphingosine kinase transmits estrogen signaling in human breast cancer cells (2003)
Sukocheva, O. A.,
Wang, L.,
Albanese, N. O.,
Pitson, S. M.,
Vadas, M.,
Xia, P.
Activation of sphingosine kinase 1 by ERK1/2-mediated phosphorylation (2003)
Pitson, S. M.,
Moretti, P. A.B.,
Zebol, J. R.,
Lynn, H. E.,
Xia, P.,
Vadas, M.,
...
Sphingosine kinase transmits estrogen signaling in human breast cancer cells (2003)
Sukocheva, O. A.,
Wang, L.,
Albanese, N. O.,
Pitson, S. M.,
Vadas, M.,
Xia, P.
Sphingosine kinase interacts with TRAF2 and dissects tumor necrosis factor-a signaling (2002)
Xia, P.,
Wang, L.,
Moretti, P. A.,
Albanese, N. O.,
Chai, F.,
Pitson, S. M.,
...
Sphingosine kinase interacts with TRAF2 and dissects tumor necrosis factor-a signaling (2002)
Xia, P.,
Wang, L.,
Moretti, P. A.,
Albanese, N. O.,
Chai, F.,
Pitson, S. M.,
...
Human sphingosine kinase: purification, molecular cloning and characterization of the native and recombinant enzymes (2000)
Pitson, S. M.,
D'Andrea, R. J.,
Vandeleur, L.,
Moretti, P.,
Xia, P.,
Gamble, J. R.,
...
An oncogenic role of sphingosine kinase (2000)
Xia, P.,
Gamble, J. R.,
Wang, L.,
Pitson, S. M.,
Moretti, P.,
Wattenberg, B. W.,
...
Expression of a catalytically inactive sphingosine kinase mutant blocks agonist-induced sphingosine kinase activation (2000)
Pitson, S. M.,
Moretti, P.,
Zebol, J. R.,
Xia, P.,
Gamble, J. R.,
Vadas, M. A.,
...
Human sphingosine kinase: purification, molecular cloning and characterization of the native and recombinant enzymes (2000)
Pitson, S. M.,
D'Andrea, R. J.,
Vandeleur, L.,
Moretti, P.,
Xia, P.,
Gamble, J. R.,
...
An oncogenic role of sphingosine kinase (2000)
Xia, P.,
Gamble, J. R.,
Wang, L.,
Pitson, S. M.,
Moretti, P.,
Wattenberg, B. W.,
...
Expression of a catalytically inactive sphingosine kinase mutant blocks agonist-induced sphingosine kinase activation (2000)
Pitson, S. M.,
Moretti, P.,
Zebol, J. R.,
Xia, P.,
Gamble, J. R.,
Vadas, M. A.,
...
Tumor necrosis factor-alpha induces adhesion molecule expression through the sphingosine kinase pathway (1998)
Xia, P.,
Gamble, J. R.,
Rye, K. A.,
Wang, L.,
Hii, C. S.T.,
Cockerill, P.,
...
Tumor necrosis factor-alpha induces adhesion molecule expression through the sphingosine kinase pathway (1998)
Xia, P.,
Gamble, J. R.,
Rye, K. A.,
Wang, L.,
Hii, C. S.T.,
Cockerill, P.,
...
Identification of the mechanism for the inhibition of Na+,K(+)-adenosine triphosphatase by hyperglycemia involving activation of protein kinase C and cytosolic phospholipase A2.
Xia, P,
Kramer, R M,
King, G L
Inhibition of Na+,K(+)-ATPase activity by hyperglycemia could be an important etiological factor of chronic complications in diabetic patients. The biochemical mechanism underlying hyperglycemia's...
Complement fixation by pemphigus antibody. V. Assembly of the membrane attack complex on cultured human keratinocytes.
Xia, P,
Jordon, R E,
Geoghegan, W D
Previous studies have shown that pemphigus vulgaris (PV) IgG will fix early complement components (C1q, C4, and C3) to cultured murine epidermal cell surfaces and that PV IgG and complement alter...
Characterization of vascular endothelial growth factor's effect on the activation of protein kinase C, its isoforms, and endothelial cell growth.
Xia, P,
Aiello, L P,
Ishii, H,
Jiang, Z Y,
Park, D J,
Robinson, G S,
...
Vascular endothelial growth factor (VEGF) is a potent endothelial cell mitogen which mediates its effects by binding to tyrosine kinase receptors. We have characterized the VEGF-activated...
Human sphingosine kinase: purification, molecular cloning and characterization of the native and recombinant enzymes.
Pitson, S M,
D'andrea, R J,
Vandeleur, L,
Moretti, P A,
Xia, P,
Gamble, J R,
...
Sphingosine 1-phosphate (S1P) is a novel lipid messenger that has important roles in a wide variety of mammalian cellular processes including growth, differentiation and death. Basal levels of S1P in...
Diffusion coefficients in the lateral intercellular spaces of Madin-Darby canine kidney cell epithelium determined with caged compounds.
Xia, P,
Bungay, P M,
Gibson, C C,
Kovbasnjuk, O N,
Spring, K R
The diffusion coefficients of two caged fluorescent dyes were measured in free solution and in the lateral intercellular spaces (LIS) of cultured Madin-Darby canine kidney (MDCK) cells after...
Identification of the mechanism for the inhibition of Na+,K(+)-adenosine triphosphatase by hyperglycemia involving activation of protein kinase C and cytosolic phospholipase A2.
Xia, P,
Kramer, R M,
King, G L
Inhibition of Na+,K(+)-ATPase activity by hyperglycemia could be an important etiological factor of chronic complications in diabetic patients. The biochemical mechanism underlying hyperglycemia's...
Complement fixation by pemphigus antibody. V. Assembly of the membrane attack complex on cultured human keratinocytes.
Xia, P,
Jordon, R E,
Geoghegan, W D
Previous studies have shown that pemphigus vulgaris (PV) IgG will fix early complement components (C1q, C4, and C3) to cultured murine epidermal cell surfaces and that PV IgG and complement alter...
Characterization of vascular endothelial growth factor's effect on the activation of protein kinase C, its isoforms, and endothelial cell growth.
Xia, P,
Aiello, L P,
Ishii, H,
Jiang, Z Y,
Park, D J,
Robinson, G S,
...
Vascular endothelial growth factor (VEGF) is a potent endothelial cell mitogen which mediates its effects by binding to tyrosine kinase receptors. We have characterized the VEGF-activated...
Human sphingosine kinase: purification, molecular cloning and characterization of the native and recombinant enzymes.
Pitson, S M,
D'andrea, R J,
Vandeleur, L,
Moretti, P A,
Xia, P,
Gamble, J R,
...
Sphingosine 1-phosphate (S1P) is a novel lipid messenger that has important roles in a wide variety of mammalian cellular processes including growth, differentiation and death. Basal levels of S1P in...
Diffusion coefficients in the lateral intercellular spaces of Madin-Darby canine kidney cell epithelium determined with caged compounds.
Xia, P,
Bungay, P M,
Gibson, C C,
Kovbasnjuk, O N,
Spring, K R
The diffusion coefficients of two caged fluorescent dyes were measured in free solution and in the lateral intercellular spaces (LIS) of cultured Madin-Darby canine kidney (MDCK) cells after...