Alterations in Notch signaling in neoplastic lesions of the human cervix.
Zagouras, P, Stifani, S, Blaumueller, C M, Carcangiu, M L, Artavanis-Tsakonas, S
The development of cancer is a cellular process that reflects and is partly driven by alterations in cell determination. Mutations in various molecules responsible for cell determination have been...
Neoplastic transformation by truncated alleles of human NOTCH1/TAN1 and NOTCH2.
Capobianco, A J, Zagouras, P, Blaumueller, C M, Artavanis-Tsakonas, S, Bishop, J M
The Notch genes of Drosophila melanogaster and vertebrates encode transmembrane receptors that help determine cell fate during development. Although ligands for Notch proteins have been identified,...
Previous studies have shown that trimers of the vesicular stomatitis virus glycoprotein (VSV G protein) are in rapid equilibrium with monomeric subunits after folding and assembly in the endoplasmic...
Zagouras, P, Ruusala, A, Rose, J K
The vesicular stomatitis virus (VSV) glycoprotein (G) forms noncovalently linked trimers in the endoplasmic reticulum (ER) prior to transport to the cell surface. Here we examined the formation of...
A fusion-defective mutant of the vesicular stomatitis virus glycoprotein.
Whitt, M A, Zagouras, P, Crise, B, Rose, J K
We have recently described an assay in which a temperature-sensitive mutant of vesicular stomatitis virus (VSV; mutant tsO45), encoding a glycoprotein that is not transported to the cell surface, can...
Crise, B, Ruusala, A, Zagouras, P, Shaw, A, Rose, J K
The vesicular stomatitis virus glycoprotein forms noncovalently linked trimers in the endoplasmic reticulum before being transported to the Golgi apparatus. The experiments reported here were...
Alterations in Notch signaling in neoplastic lesions of the human cervix.
Zagouras, P, Stifani, S, Blaumueller, C M, Carcangiu, M L, Artavanis-Tsakonas, S
The development of cancer is a cellular process that reflects and is partly driven by alterations in cell determination. Mutations in various molecules responsible for cell determination have been...
Neoplastic transformation by truncated alleles of human NOTCH1/TAN1 and NOTCH2.
Capobianco, A J, Zagouras, P, Blaumueller, C M, Artavanis-Tsakonas, S, Bishop, J M
The Notch genes of Drosophila melanogaster and vertebrates encode transmembrane receptors that help determine cell fate during development. Although ligands for Notch proteins have been identified,...
Previous studies have shown that trimers of the vesicular stomatitis virus glycoprotein (VSV G protein) are in rapid equilibrium with monomeric subunits after folding and assembly in the endoplasmic...
Zagouras, P, Ruusala, A, Rose, J K
The vesicular stomatitis virus (VSV) glycoprotein (G) forms noncovalently linked trimers in the endoplasmic reticulum (ER) prior to transport to the cell surface. Here we examined the formation of...
A fusion-defective mutant of the vesicular stomatitis virus glycoprotein.
Whitt, M A, Zagouras, P, Crise, B, Rose, J K
We have recently described an assay in which a temperature-sensitive mutant of vesicular stomatitis virus (VSV; mutant tsO45), encoding a glycoprotein that is not transported to the cell surface, can...
Crise, B, Ruusala, A, Zagouras, P, Shaw, A, Rose, J K
The vesicular stomatitis virus glycoprotein forms noncovalently linked trimers in the endoplasmic reticulum before being transported to the Golgi apparatus. The experiments reported here were...