PA Dawson

Hyperserotonaemia and reduced brain serotonin levels in NaSl sulphate transporter null mice (2007)

Lee, S, Kesby, JP, Muslim, MD, Steane, SE, Eyles, DW, Dawson, PA, ...

Sulphate (SO42-) is conjugated to numerous enclogenous compounds, including serotonin (5-HT). The NaSl sulphate transporter is primarily expressed in the kidney, where it maintains blood SO42-...

Genetic Polymorphisms of Human Sulfate Transporters (2007)

Dawson, PA, Markovich, D

Mutational analysis of the cystathionine beta-synthase gene: A splicing mutation, two missense mutations and an insertion in patients with homocystinuria (1998)

Gordon, RB, Cox, AJ, Dawson, PA, Emmerson, BT, Kraus, JP, Dudman, NPB

RT-PCR and direct sequence analyses were used to define mutations in the cystathionine beta-synthase (CBS) gene in two unrelated male patients with vitamin B6 nonresponsive homocystinuria. Both...

Characterisation of five missense mutations in the cystathionine beta-synthase gene from three patients with B-6-nonresponsive homocystinuria (1997)

Dawson, PA, Cox, AJ, Emmerson, BT, Dudman, NPB, Kraus, JP, Gordon, RB

Homocystinuria, due to a deficiency of the enzyme cystathionine beta-synthase (CBS), is an inborn error of sulphur-amino acid metabolism, This is an autosomal recessive disease which results in...