Goodsell, Amanda, Zhou, Fengmin, Gupta, Soumi, Singh, Manmohan, Malyala, Padma, Kazzaz, Jina, ...
Vaccination strategies that can block or limit heterosexual human immunodeficiency virus (HIV) transmissions to local and systemic tissues are the goal of much research effort. Herein, in a mouse...
Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome
Sharp, Fiona A., Ruane, Darren, Claass, Benjamin, Creagh, Emma, Harris, James, Malyala, Padma, ...
Many currently used and candidate vaccine adjuvants are particulate in nature, but their mechanism of action is not well understood. Here, we show that particulate adjuvants, including biodegradable...