During the project period we have initiated a completed studies in the following areas: (1) The crystal structure of a mouse acetylcholinesterase-fasciculin 2 complex has provided an essential...
In the initial year of the grant, we have made excellent progress in several arenas: (1) A crystal structure of a mouse acetylcholinesterase-fasciculin 2 complex has been solved. (2) Studies with...
During this year we examined oxime reactivation of organophosphate modified cholinesterases using both achiral and chiral organophosphate inhibitors. The chiral inhibitors were resolved enantiomers...
Studies on the structural of acetyicholinesterase (AChE) as a target of organophosphate toxicity continue and have yielded several leads of significance and practical outcomes. First, studies on...
Studies on the structural of acetylcholinesterase (AChE) as a target of organophosphate toxicity continue and have yielded several leads of significance and practical outcomes. First, studies on...
In the second year of the grant, we have made excellent progress in several arenas: 1) The crystal structure of a mouse acetylcholinesterase-fasciculin 2 complex has provided an essential template...