Craig R. Bush, Jennifer M. Havens, Brian M. Necela, Weidong Su, Lu Chen, Masahiro Yanagisawa, ...
and anchorage-independent growth and invasion through Matrigel-coated transwell membranes. We carried out a longitudinal two-class microarray analysis in which mRNA abundance was measured as a...
Yanagisawa, Masahiro, Anastasiadis, Panos Z.
During epithelial tumor progression, the loss of E-cadherin expression and inappropriate expression of mesenchymal cadherins coincide with increased invasiveness. Reexpression experiments have...
Vertebrate development requires ARVCF and p120 catenins and their interplay with RhoA and Rac
Fang, Xiang, Ji, Hong, Kim, Si-Wan, Park, Jae-Il, Vaught, Travis G., Anastasiadis, Panos Z., ...
Using an animal model system and depletion-rescue strategies, we have addressed the requirement and functions of armadillo repeat gene deleted in velo-cardio-facial syndrome (ARVCF) and p120 catenins...
Selective Uncoupling of P120ctn from E-Cadherin Disrupts Strong Adhesion
Thoreson, Molly A., Anastasiadis, Panos Z., Daniel, Juliet M., Ireton, Reneé C., Wheelock, Margaret J., Johnson, Keith R., ...
p120ctn is a catenin whose direct binding to the juxtamembrane domain of classical cadherins suggests a role in regulating cell–cell adhesion. The juxtamembrane domain has been implicated in a...
A novel role for p120 catenin in E-cadherin function
Ireton, Reneé C., Davis, Michael A., Van Hengel, Jolanda, Mariner, Deborah J., Barnes, Kirk, Thoreson, Molly A., ...
Îndirect evidence suggests that p120-catenin (p120) can both positively and negatively affect cadherin adhesiveness. Here we show that the p120 gene is mutated in SW48 cells, and that the cadherin...
p120 catenin induces opposing effects on tumor cell growth depending on E-cadherin expression
Soto, Edwin, Yanagisawa, Masahiro, Marlow, Laura A., Copland, John A., Perez, Edith A., Anastasiadis, Panos Z.
p120 catenin regulates the activity of the Rho family guanosine triphosphatases (including RhoA and Rac1) in an adhesion-dependent manner. Through this action, p120 promotes a sessile cellular...
Lee, Seung-Hye, Peng, I.-Feng, Ng, Yu Gie, Yanagisawa, Masahiro, Bamji, Shernaz X., Elia, Lisa P., ...
Localization of presynaptic components to synaptic sites is critical for hippocampal synapse formation. Cell adhesion–regulated signaling is important for synaptic development and function, but...
Yanagisawa, Masahiro, Huveldt, Deborah, Kreinest, Pamela, Lohse, Christine M., Cheville, John C., Parker, Alexander S., ...
p120 catenin is a cadherin-associated protein that regulates Rho GTPases and promotes the invasiveness of E-cadherin-deficient cancer cells. Multiple p120 isoforms are expressed in cells via...