Proline Racemases: Insights Into Trypanosoma Cruzi Peptides Containing D-Proline (2009)
Coatnoan, Nicolas, Berneman, Armand, Chamond, Nathalie, Minoprio, Paola
Trypanosoma cruzi proline racemases (TcPRAC) are homodimeric enzymes that interconvert the L and D-enantiomers of proline. At least two paralogous copies of proline racemase (PR) genes are present...
Coatnoan, Nicolas, Berneman, Armand, Chamond, Nathalie, Minoprio, Paola
Chagas disease, which is caused by the intracellular parasite Trypanosoma cruzi , is a neglected illness with 12-14 million reported cases in endemic geographic regions of Latin America. While the...
Yara M Gomes, Frederico GC Abath, Mineo Nakazawa, Paola Minoprio, Ioannis Vouldoukis, Loic Monjour
A 72 kDa Trypanosoma cruzi glycoprotein recognized by the 164C11 monoclonal antibody (IgM isotype) was purified by preparative electrophoresis. The antigenic preparation obtained, named TcY 72, was...
Gomes,Yara M, Abath,Frederico GC, Nakazawa,Mineo, Minoprio,Paola, Vouldoukis,Ioannis, Monjour,Loic
A 72 kDa Trypanosoma cruzi glycoprotein recognized by the 164C11 monoclonal antibody (IgM isotype) was purified by preparative electrophoresis. The antigenic preparation obtained, named TcY 72, was...
Silva, Anabela Cordeiro Da, Lima, Eduardo Cesar Santos, Vlcentelli, Marie-Heléne, Minoprio, Paola, Martinez-A, C.
BALB.xid mice, carrying an X-linked mutation leading to the absence of CD5+ B cells, are highly resistant to Trypanosoma cruzi Infection. These mice clear blood parasites In the acute phase of...
Skewed V{beta} TCR repertoire of CD8+ T cells in murine Trypanosoma cruzi infection (1994)
Coutinho, Antonio, Hontebeyrle-Joskowicz, Mirellle, Minoprio, Paola, Eisen, Harvey, Bandeira, Antonio
We have followed CD4 and CD8 TCR Vβ repertoires during the acute phase of Trypanosoma cruzi infection in a resistant mouse strain (C57BL/6). No major changes were found in the Vfl TCR...
Theileria annulata in CD5+ Macrophages and B1 B Cells
Moreau, Marie-Françoise, Thibaud, Jean-Laurent, Miled, Leila Ben, Chaussepied, Marie, Baumgartner, Martin, Davis, William C., ...
Theileria parasites infect and transform bovine leukocytes. We have analyzed laboratory-established Theileria sp.-infected leukocyte lines and observed that transformed macrophages express CD5....
Buschiazzo, Alejandro, Goytia, Maira, Schaeffer, Francis, Degrave, Wim, Shepard, William, Grégoire, Christophe, ...
Amino acid racemases catalyze the stereoinversion of the chiral Cα to produce the d-enantiomers that participate in biological processes, such as cell wall construction in prokaryotes. Within this...
Goytia, Maira, Chamond, Nathalie, Cosson, Alain, Coatnoan, Nicolas, Hermant, Daniel, Berneman, Armand, ...
The first eukaryotic proline racemase (PRAC), isolated from the human Trypanosoma cruzi pathogen, is a validated therapeutic target against Chagas' disease. This essential enzyme is implicated in...