Pascale Bourhy, Laurence Salaün, Aurélie Lajus, Claudine Médigue, Mathieu Picardeau
A genomic island of the pathogen Leptospira interrogans
The OmpA-Like Protein Loa22 Is Essential for Leptospiral Virulence (2007)
Paula Ristow, Pascale Bourhy, Claudio Pereira Figueira, Michel Huerre, Patrick Ave, ...
Pathogenic mechanisms of Leptospira interrogans, the causal agent of leptospirosis, remain largely unknown. This is mainly due to the lack of tools for genetic manipulations of pathogenic species. In...
Girons, Isabelle Saint, Bourhy, Pascale, Ottone, Catherine, Picardeau, Mathieu, Yelton, David, Hendrix, Roger W., ...
We have discovered that LE1, one of the plaque-forming phages previously described as lytic for the Leptospira biflexa saprophytic spirochete (I. Saint Girons, D. Margarita, P. Amouriaux, and G....
Bourhy, Pascale, Louvel, Hélène, Saint Girons, Isabelle, Picardeau, Mathieu
The recent availability of the complete genome sequences of Leptospira interrogans, the agent of leptospirosis, has allowed the identification of several putative virulence factors. However, to our...
Mazouni, Khalil, Pehau-Arnaudet, Gérard, England, Patrick, Bourhy, Pascale, Saint Girons, Isabelle, Picardeau, Mathieu
The analysis of the genome of Leptospira spp., a group of bacteria of the phylum of spirochetes with several unique evolutionary and morphological features, has allowed the identification of a gene...
Bourhy, Pascale, Frangeul, Lionel, Couvé, Elisabeth, Glaser, Philippe, Saint Girons, Isabelle, Picardeau, Mathieu
The first and, to date, only extrachromosomal circular replicon identified in the spirochete Leptospira is the LE1 prophage from Leptospira biflexa. The 74-kb LE1 genome has a GC content of 36%,...
Girons, Isabelle Saint, Bourhy, Pascale, Ottone, Catherine, Picardeau, Mathieu, Yelton, David, Hendrix, Roger W., ...
We have discovered that LE1, one of the plaque-forming phages previously described as lytic for the Leptospira biflexa saprophytic spirochete (I. Saint Girons, D. Margarita, P. Amouriaux, and G....
Bourhy, Pascale, Louvel, Hélène, Saint Girons, Isabelle, Picardeau, Mathieu
The recent availability of the complete genome sequences of Leptospira interrogans, the agent of leptospirosis, has allowed the identification of several putative virulence factors. However, to our...
Bourhy, Pascale, Frangeul, Lionel, Couvé, Elisabeth, Glaser, Philippe, Saint Girons, Isabelle, Picardeau, Mathieu
The first and, to date, only extrachromosomal circular replicon identified in the spirochete Leptospira is the LE1 prophage from Leptospira biflexa. The 74-kb LE1 genome has a GC content of 36%,...
Mazouni, Khalil, Pehau-Arnaudet, Gérard, England, Patrick, Bourhy, Pascale, Saint Girons, Isabelle, Picardeau, Mathieu
The analysis of the genome of Leptospira spp., a group of bacteria of the phylum of spirochetes with several unique evolutionary and morphological features, has allowed the identification of a gene...
Bourhy, Pascale, Salaün, Laurence, Lajus, Aurélie, Médigue, Claudine, Boursaux-Eude, Caroline, Picardeau, Mathieu
An examination of the two Leptospira interrogans genomes sequenced so far reveals few genetic differences, including an extra DNA region, 54 kb in length, in L. interrogans serovar Lai. This locus...
The OmpA-Like Protein Loa22 Is Essential for Leptospiral Virulence
Ristow, Paula, Bourhy, Pascale, Da Cruz McBride, Flávia Weykamp, Figueira, Claudio Pereira, Huerre, Michel, Ave, Patrick, ...
Pathogenic mechanisms of Leptospira interrogans, the causal agent of leptospirosis, remain largely unknown. This is mainly due to the lack of tools for genetic manipulations of pathogenic species. In...