Patrice François

Transcriptome analysis of the responses of Staphylococcus aureusto antimicrobial peptides and characterization of the roles of vraDEand vraSRin antimicrobial resistance (2009)

Pietiäinen, Milla, François, Patrice, Hyyryläinen, Hanne-Leena, Tangomo, Manuela, Sass, Vera, Sahl, Hans-Georg, ...

Abstract Background Understanding how pathogens respond to antimicrobial peptides, and how this compares to currently available antibiotics, is crucial for optimizing antimicrobial therapy....

Effect of a glucose impulse on the CcpA regulon in Staphylococcus aureus (2009)

Seidl, Kati, Müller, Susanne, François, Patrice, Kriebitzsch, Carsten, Schrenzel, Jacques, Engelmann, Susanne, ...

Abstract Background The catabolite control protein A (CcpA) is a member of the LacI/GalR family of transcriptional regulators controlling carbon-metabolism pathways in low-GC Gram-positive bacteria....

Genomic analysis of an emerging multiresistant Staphylococcus aureusstrain rapidly spreading in cystic fibrosis patients revealed the presence of an antibiotic inducible bacteriophage (2009)

Rolain, Jean-Marc, François, Patrice, Hernandez, David, Bittar, Fadi, Richet, Hervé, Fournous, Ghislain, ...

Abstract Background Staphylococcus aureus is a major human pathogen responsible for a variety of nosocomial and community-acquired infections. Recent reports show that the prevalence of...

A dynamic exercise programme to improve patients' disability in rheumatoid arthritis: a prospective randomized controlled trial (2009)

Baillet, Athan, Payraud, Elodie, Niderprim, Virginie-Aurélie, Nissen, Michael J., Allenet, Benoit, François, Patrice, ...

Objective. To evaluate the functional, clinical, radiological and quality of life outcomes of a 4-week dynamic exercise programme (DEP) in RA. Methods. Patients matched on the principal medico-social...

Validation of a French hospitalized patients' satisfaction questionnaire: the QSH-45 (2009)

Antoniotti, Stéphanie, Baumstarck-Barrau, Karine, Siméoni, Marie-Claude, Sapin, Christophe, Labarère, José, Gerbaud, Laurent, ...

Objective To develop a generic French self-administered instrument for measuring hospitalized patients' satisfaction based on the patient's point of view: the questionnaire for satisfaction of...

Biology Direct BioMed Central (2009)

Jean-marc Rolain, Patrice François, David Hern, Fadi Bittar, Hervé Richet, Ghislain Fournous, ...

Genomic analysis of an emerging multiresistant Staphylococcus aureus strain rapidly spreading in cystic fibrosis patients revealed the presence of an antibiotic inducible bacteriophage

De novo bacterial genome sequencing: Millions of very short reads assembled on a desktop computer (2008)

Hernandez, David, François, Patrice, Farinelli, Laurent, Østerås, Magne, Schrenzel, Jacques

Novel high-throughput DNA sequencing technologies allow researchers to characterize a bacterial genome during a single experiment and at a moderate cost. However, the increase in sequencing...

Exploring glycopeptide-resistance in Staphylococcus aureus: a combined proteomics and transcriptomics approach for the identification of resistance-related markers (2006)

Scherl, Alexander, François, Patrice, Charbonnier, Yvan, Deshusses, Jacques M, Koessler, Thibaud, Huyghe, Antoine, ...

Abstract Background To unravel molecular targets involved in glycopeptide resistance, three isogenic strains of Staphylococcus aureus with different susceptibility levels to vancomycin or teicoplanin...

A generic approach for the design of whole-genome oligoarrays, validated for genomotyping, deletion mapping and gene expression analysis on Staphylococcus aureus (2005)

Charbonnier, Yvan, Gettler, Brian, François, Patrice, Bento, Manuela, Renzoni, Adriana, Vaudaux, Pierre, ...

Abstract Background DNA microarray technology is widely used to determine the expression levels of thousands of genes in a single experiment, for a broad range of organisms. Optimal design of...

analysis on (2005)

Bmc Genomics, Biomed Central, Yvan Charbonnier, Brian Gettler, Patrice François, Manuela Bento, ...

Research article A generic approach for the design of whole-genome oligoarrays, validated for genomotyping, deletion mapping and gene expression

Reassessing the Role of Staphylococcus aureus Clumping Factor and Fibronectin-Binding Protein by Expression in Lactococcus lactis

Que, Yok-Ai, François, Patrice, Haefliger, Jacques-Antoine, Entenza, José-Manuel, Vaudaux, Pierre, Moreillon, Philippe

Since Staphylococcus aureus expresses multiple pathogenic factors, studying their individual roles in single-gene-knockout mutants is difficult. To circumvent this problem, S. aureus clumping factor...

Reassessing the Role of Staphylococcus aureus Clumping Factor and Fibronectin-Binding Protein by Expression in Lactococcus lactis

Que, Yok-Ai, François, Patrice, Haefliger, Jacques-Antoine, Entenza, José-Manuel, Vaudaux, Pierre, Moreillon, Philippe

Since Staphylococcus aureus expresses multiple pathogenic factors, studying their individual roles in single-gene-knockout mutants is difficult. To circumvent this problem, S. aureus clumping factor...

Transcriptomic and Functional Analysis of an Autolysis-Deficient, Teicoplanin-Resistant Derivative of Methicillin-Resistant Staphylococcus aureus†

Renzoni, Adriana, Barras, Christine, François, Patrice, Charbonnier, Yvan, Huggler, Elzbieta, Garzoni, Christian, ...

The molecular basis of glycopeptide-intermediate S. aureus (GISA) isolates is not well defined though frequently involves phenotypes such as thickened cell walls and decreased autolysis. We have...

Fibrinogen and fibronectin binding cooperate for valve infection and invasion in Staphylococcus aureus experimental endocarditis

Que, Yok-Ai, Haefliger, Jacques-Antoine, Piroth, Lionel, François, Patrice, Widmer, Eleonora, Entenza, José M., ...

The expression of Staphylococcus aureus adhesins in Lactococcus lactis identified clumping factor A (ClfA) and fibronectin-binding protein A (FnBPA) as critical for valve colonization in rats with...

De novo bacterial genome sequencing: Millions of very short reads assembled on a desktop computer

Hernandez, David, François, Patrice, Farinelli, Laurent, Østerås, Magne, Schrenzel, Jacques

Novel high-throughput DNA sequencing technologies allow researchers to characterize a bacterial genome during a single experiment and at a moderate cost. However, the increase in sequencing...

Microarray Comparative Genomic Hybridisation Analysis Incorporating Genomic Organisation, and Application to Enterobacterial Plant Pathogens

Pritchard, Leighton, Liu, Hui, Booth, Clare, Douglas, Emma, François, Patrice, Schrenzel, Jacques, ...

Microarray comparative genomic hybridisation (aCGH) provides an estimate of the relative abundance of genomic DNA (gDNA) taken from comparator and reference organisms by hybridisation to a microarray...

Identification by Genomic and Genetic Analysis of Two New Genes Playing a Key Role in Intermediate Glycopeptide Resistance in Staphylococcus aureus▿

Renzoni, Adriana, Kelley, William L., Barras, Christine, Monod, Antoinette, Huggler, Elzbieta, François, Patrice, ...

Endogenous, low-level glycopeptide resistance in Staphylococcus aureus results from multifactorial genetic changes. Comparative genomic hybridization analysis revealed the specific deletion of a...