Direct Inference of SNP Heterozygosity Rates and Resolution of LOH Detection (2007)
Xiaohong Li, Steven G. Self, Patricia C. Galipeau, Thomas G. Paulson, Brian J. Reid
Single nucleotide polymorphisms (SNPs) have been increasingly utilized to investigate somatic genetic abnormalities in premalignancy and cancer. LOH is a common alteration observed during cancer...
Patricia C. Galipeau, Xiaohong Li, Patricia L. Blount, Carlo C. Maley, Carissa A. Sanchez, Robert D. Odze, ...
BackgroundSomatic genetic CDKN2A, TP53, and DNA content abnormalities are common in many human cancers and their precursors, including esophageal adenocarcinoma (EA) and Barrett's esophagus (BE),...
Rudolph, Rebecca E., Vaughan, Thomas L., Kristal, Alan R., Blount, Patricia L., Levine, Douglas S., Galipeau, Patricia C., ...
Background: Persons with Barrett’s esophagus have a substantially greater risk of esophageal adenocarcinoma than the general population. Higher serum selenium levels have been associated with a...
Genome-wide Detection of Allelic Imbalance Using Human SNPs and High-density DNA Arrays (2000)
Mei, Rui, Galipeau, Patricia C., Prass, Cynthia, Berno, Anthony, Ghandour, Ghassan, Patil, Nila, ...
Galipeau, Patricia C., Prevo, Laura J., Sanchez, Carissa A., Longton, Gary M., Reid, Brian J.
BACKGROUND: Abnormalities involving the p16 (also known as cyclin-dependent kinase N2 [CDKN2], p16 [INK4a], or MTS1) and p53 (also known as TP53) tumor suppressor genes are highly...
Paulson, Thomas G., Galipeau, Patricia C., Reid, Brian J.
Loss of heterozygosity (LOH) is a common genetic lesion found in many human neoplasms. Extending investigation of LOH to large-scale clinical and public health science studies has proven difficult...
Paulson, Thomas G., Galipeau, Patricia C., Reid, Brian J.
Loss of heterozygosity (LOH) is a common genetic lesion found in many human neoplasms. Extending investigation of LOH to large-scale clinical and public health science studies has proven difficult...
NSAIDs Modulate CDKN2A, TP53, and DNA Content Risk for Progression to Esophageal Adenocarcinoma
Galipeau, Patricia C, Li, Xiaohong, Blount, Patricia L, Maley, Carlo C, Sanchez, Carissa A, Odze, Robert D, ...
In a ten-year study of people with Barrett's esophagus, nonsteroidal anti-inflamatory drugs were associated with reduced risk of esophageal adenocarcinoma, especially in patients with multiple...
Direct Inference of SNP Heterozygosity Rates and Resolution of LOH Detection
Li, Xiaohong, Self, Steven G, Galipeau, Patricia C, Paulson, Thomas G, Reid, Brian J
Single nucleotide polymorphisms (SNPs) have been increasingly utilized to investigate somatic genetic abnormalities in premalignancy and cancer. LOH is a common alteration observed during cancer...