Patricia T. Bozza

Intravenous glutamine decreases lung and distal organ injury in an experimental model of abdominal sepsis (2009)

Oliveira, Gisele P, Oliveira, Mariana BG, Santos, Raquel S, Lima, Letícia D, Dias, Cristina M, AB' Saber, Alexandre M, ...

Abstract Introduction The protective effect of glutamine, as a pharmacological agent against lung injury, has been reported in experimental sepsis; however, its efficacy at improving oxygenation and...

RAPID COMMUNICATION Regulation of Allergic Inflammation and Eosinophil Recruitment in Mice Lacking the Transcription Factor NFAT1: Role of Interleukin-4 (IL-4) and IL-5 (2008)

P. B. Viola, Er Kiani, Patricia T. Bozza, Anjana Rao

Transcription factors of the NFAT (nuclear factor of activated T cells) family regulate the expression of many genes encoding immunoregulatory cytokines and cell surface proteins during the immune...

Multiplex cytokine profile from dengue patients: MIP-1beta and IFN-gamma as predictive factors for severity (2008)

Bozza, Fernando A, Cruz, Oswaldo G, Zagne, Sonia MO, Azeredo, Elzinandes L, Nogueira, Rita MR, Assis, Edson F, ...

Abstract Background Dengue virus pathogenesis is not yet fully understood and the identification of patients at high risk for developing severe disease forms is still a great challenge in dengue...

Mechanisms Of Formation And Function Of Eosinophil Lipid Bodies: Inducible Intracellular Sites Involved In Arachidonic Acid Metabolism (1997)

Bozza, Patricia T., Yu, Wengui, Weller, Peter F.

Lipid bodies, inducible lipid-rich cytoplasmic inclusions, are characteristically abundant in cells associated with inflammation, including eosinophils. Here we reviewed the formation and function of...

A Role For Lymphocytes And Cytokines On The Eosinophil Migration Induced By LPS (1997)

Penido, Carmen M., Larangeira, Andrea P., Silva, Adriana R., Bozza, Patricia T.

In the present work we review the existing evidence for a LPS-induced cytokine-mediated eosinophil accumulation in a model of acute inflammation. Intrathoracic administration of LPS into rodents...

Mechanisms of formation and function of eosinophil lipid bodies: inducible intracellular sites involved in arachidonic acid metabolism (1997)

Bozza,Patricia T, Yu,Wengui, Weller,Peter F

Lipid bodies, inducible lipid-rich cytoplasmic inclusions, are characteristically abundant in cells associated with inflammation, including eosinophils. Here we reviewed the formation and function of...

Eosinophil Lipid Bodies: Specific, Inducible Intracellular Sites for Enhanced Eicosanoid Formation

Bozza, Patricia T., Yu,  Wengui, Penrose, John F., Morgan, Ellen S., Dvorak, Ann M., Weller, Peter F.

The specific intracellular sites at which enzymes act to generate arachidonate-derived eicosanoid mediators of inflammation are uncertain. We evaluated the formation and function of cytoplasmic lipid...

Multiplex cytokine profile from dengue patients: MIP-1beta and IFN-gamma as predictive factors for severity

Bozza, Fernando A, Cruz, Oswaldo G, Zagne, Sonia MO, Azeredo, Elzinandes L, Nogueira, Rita MR, Assis, Edson F, ...

Intravenous glutamine decreases lung and distal organ injury in an experimental model of abdominal sepsis

Oliveira, Gisele P, Oliveira, Mariana BG, Santos, Raquel S, Lima, Letícia D, Dias, Cristina M, AB' Saber, Alexandre M, ...

Dengue Virus Capsid Protein Usurps Lipid Droplets for Viral Particle Formation

Samsa, Marcelo M., Mondotte, Juan A., Iglesias, Nestor G., Assunção-Miranda, Iranaia, Barbosa-Lima, Giselle, Da Poian, Andrea T., ...

Dengue virus is responsible for the highest rates of disease and mortality among the members of the Flavivirus genus. Dengue epidemics are still occurring around the world, indicating an urgent need...