Patrick A. D. Grimont

Ceftriaxone-resistant Salmonella enterica serotype Newport, France (2008)

Egorova, Svetlana, Timinouni, Mohammed, Demartin, Marie, Granier, Sophie A., Whichard, Jean M., Sangal, Vartul, ...

The multidrug-resistant (MDR) Salmonella enterica serotype Newport strain that produces CMY-2 β-lactamase(Newport MDR-AmpC) was the source of sporadic cases and outbreaks in humans in France during...

Molecular and Phenotypic Characterization of Potentially New Shigella dysenteriae Serotype

Coimbra, Roney S., Lenormand, Pascal, Grimont, Francine, Bouvet, Philippe, Matsushita, Shigeru, Grimont, Patrick A. D.

From September 1997 to November 1998, the French National Center for Salmonella and Shigella received 22 Shigella isolates recovered from 22 different patients suffering from dysentery. None of these...

Clonal Relationships among Shigella Serotypes Suggested by Cryptic Flagellin Gene Polymorphism

Coimbra, Roney S., Lefevre, Martine, Grimont, Francine, Grimont, Patrick A. D.

The presence of cryptic fliC alleles in the genomes of 120 strains representative of the four Shigella species was investigated. One fragment was obtained by PCR amplification of fliC, with a size...

Restriction Fragment Length Polymorphism Analysis of Some Flagellin Genes of Salmonella enterica

Dauga, Catherine, Zabrovskaia, Anna, Grimont, Patrick A. D.

Salmonellae often have the ability to express two different flagellar antigen specificities (phase 1 and phase 2). At the cell level, only one flagellar phase is expressed at a time. Two genes, fliC,...

Genotypic Characteristics of Two Serotypes of Bartonella henselae

La Scola, Bernard, Liang, Zhongxing, Zeaiter, Zaher, Houpikian, Pierre, Grimont, Patrick A. D., Raoult, Didier

The study of 16S rRNA gene sequences of all isolates of Bartonella henselae obtained in our laboratory and others from human patients or cats has revealed two genotypes according to the sequence of...

Persistent Endemicity of Salmonella bongori 48:z35:− in Southern Italy: Molecular Characterization of Human, Animal, and Environmental Isolates

Giammanco, Giovanni M., Pignato, Sarina, Mammina, Caterina, Grimont, Francine, Grimont, Patrick A. D., Nastasi, Antonino, ...

From 1984 to 1999, we collected 31 isolates of the rare serovar Salmonella bongori 48:z35:− in southern Italy. Twenty-four of the isolates were from cases of acute enteritis in humans. Pulsed-field...

Identification of Major Streptococcal Species by rrn-Amplified Ribosomal DNA Restriction Analysis

Schlegel, Laurent, Grimont, Francine, Grimont, Patrick A. D., Bouvet, Anne

Amplified ribosomal DNA restriction analysis (rrn-ARDRA) is based on PCR amplification and restriction of a fragment of rRNA genes including 16S and 23S genes and the intergenic spacer. rrn-ARDRA was...

Genotypic and Phenotypic Characteristics of Corynebacterium diphtheriae Strains Isolated from Patients in Belarus during an Epidemic Period

Titov, Leonid, Kolodkina, Valentina, Dronina, Alina, Grimont, Francine, Grimont, Patrick A. D., Lejay-Collin, Monique, ...

One hundred two Corynebacterium diphtheriae strains (93 of the gravis biotype and nine of the mitis biotype) isolated from clinical cases during the Belarus diphtheria epidemic were characterized by...

Bacteremia Caused by Acinetobacter ursingii

Loubinoux, Julien, Mihaila-Amrouche, Liliana, Le Fleche, Anne, Pigne, Etienne, Huchon, Gerard, Grimont, Patrick A. D., ...

Acinetobacter ursingii has not been reported in infectious processes apart from its recent description as a new species. A bacteremia caused by A. ursingii in a patient with a pulmonary...

Characterization of Shiga Toxin-Producing Escherichia coli O157:H7 Isolated in Italy and in France

Giammanco, Giovanni M., Pignato, Sarina, Grimont, Francine, Grimont, Patrick A. D., Caprioli, Alfredo, Morabito, Stefano, ...

Twenty-one Escherichia coli O157:H7 strains isolated in northern Italy from sporadic cases of hemolytic-uremic syndrome and from cattle and food were characterized by virulence gene analysis,...

Pyrazines Responsible for the Potatolike Odor Produced by Some Serratia and Cedecea Strains

Gallois, Annie, Grimont, Patrick A. D.

The pyrazines responsible for the potatolike odor produced by some Serratia and Cedecea cultures were identified by gas-liquid chromatography (with flame ionization and thermoionic ionization...

SHV-12-Like Extended-Spectrum-β-Lactamase-Producing Strains of Salmonella enterica Serotypes Babelsberg and Enteritidis Isolated in France among Infants Adopted from Mali

Weill, François-Xavier, Demartin, Marie, Tandé, Didier, Espié, Emmanuelle, Rakotoarivony, Ignace, Grimont, Patrick A. D.

From December 2002 to June 2003, 14 cultures of Salmonella enterica serotype Babelsberg and 6 cultures of serotype Enteritidis, isolated in France from internationally adopted children, were...

Extended-Spectrum-β-Lactamase (TEM-52)-Producing Strains of Salmonella enterica of Various Serotypes Isolated in France

Weill, François-Xavier, Demartin, Marie, Fabre, Laëtitia, Grimont, Patrick A. D.

From 2002 to 2003, four isolates of Salmonella enterica serotypes Typhimurium, Enteritidis, Blockley, and Panama, isolated in France from patients with gastroenteritis, were found to produce...

Endemic, Epidemic Clone of Salmonella enterica Serovar Typhi Harboring a Single Multidrug-Resistant Plasmid in Vietnam between 1995 and 2002

Le, Thi Anh Hong, Lejay-Collin, Monique, Grimont, Patrick A. D., Hoang, Thuy Long, Nguyen, Thi Vinh, Grimont, Francine, ...

Salmonella enterica serovar Typhi strains resistant to ampicillin, chloramphenicol, tetracyclines, streptomycin, and cotrimoxazole, isolated from sporadic cases and minor outbreaks in Vietnam between...

Molecular Serotyping of Klebsiella Species Isolates by Restriction of the Amplified Capsular Antigen Gene Cluster

Brisse, Sylvain, Issenhuth-Jeanjean, Sylvie, Grimont, Patrick A. D.

The objective of the present work was to develop a molecular method that would enable determination of the capsular serotypes of Klebsiella isolates without the use of antiserum. PCR amplification of...

Emergence of Extended-Spectrum-β-Lactamase (CTX-M-9)-Producing Multiresistant Strains of Salmonella enterica Serotype Virchow in Poultry and Humans in France

Weill, François-Xavier, Lailler, Renaud, Praud, Karine, Kérouanton, Annaëlle, Fabre, Laëtitia, Brisabois, Anne, ...

During 2002 to 2003, eight Salmonella enterica serotype Virchow poultry and poultry product isolates from various sources (chicken farms, poultry slaughterhouse, or retail store) and one S. enterica...

Corynebacterium ulcerans in an Immunocompromised Patient with Diphtheria and Her Dog

Lartigue, Marie-Frédérique, Monnet, Xavier, Le Flèche, Anne, Grimont, Patrick A. D., Benet, Jean-Jacques, Durrbach, Antoine, ...

Corynebacterium ulcerans causes zoonotic infections, such as diphtheria and extrapharyngeal infections. We report here the first case of a diphtheria-like illness caused by C. ulcerans in France and...

Endocarditis Due to a New Rod-Shaped Neisseria sp.

Michaux-Charachon, Sylvie, Lavigne, Jean-Philippe, Le Flèche, Anne, Bouziges, Nicole, Sotto, Albert, Grimont, Patrick A. D.

We report the first case of pacemaker endocarditis due to a new rod-shaped Neisseria sp. isolated from blood culture. On the basis of rrs sequencing, the isolate was found to be most closely related...

Nosocomial Outbreak Caused by Salmonella enterica Serotype Livingstone Producing CTX-M-27 Extended-Spectrum β-Lactamase in a Neonatal Unit in Sousse, Tunisia

Bouallègue-Godet, Olfa, Salem, Youssef Ben, Fabre, Laëtitia, Demartin, Marie, Grimont, Patrick A. D., Mzoughi, Ridha, ...

In this study, we report an outbreak of Salmonella enterica serotype Livingstone resistant to extended-spectrum cephalosporins that occurred in a neonatal ward of the maternity department of Farhat...

Bacteremia Caused by an Undescribed Species of Janibacter

Loubinoux, Julien, Rio, Bernard, Mihaila, Liliana, Foïs, Elena, Le Fleche, Anne, Grimont, Patrick A. D., ...

A yellow-pigmented rod- to coccoid-shaped coryneform microorganism was isolated from the blood of a patient with acute myeloid leukemia. It was identified by 16S rRNA gene sequencing as a previously...

Six Groups of the OXY β-Lactamase Evolved over Millions of Years in Klebsiella oxytoca

Fevre, Cindy, Jbel, Mehdi, Passet, Virginie, Weill, François-Xavier, Grimont, Patrick A. D., Brisse, Sylvain

The diversity and evolution of the class A OXY β-lactamase from Klebsiella oxytoca were investigated and compared to housekeeping gene diversity. The entire blaOXY coding region was sequenced in 18...

Multilocus Sequence Typing of Klebsiella pneumoniae Nosocomial Isolates

Diancourt, Laure, Passet, Virginie, Verhoef, Jan, Grimont, Patrick A. D., Brisse, Sylvain

A multilocus sequence typing (MLST) scheme was developed for Klebsiella pneumoniae. Sequences of seven housekeeping genes were obtained for 67 K. pneumoniae strains, including 19 ceftazidime- and...

Variants of the Klebsiella pneumoniae OKP Chromosomal Beta-Lactamase Are Divided into Two Main Groups, OKP-A and OKP-B

Fevre, Cindy, Passet, Virginie, Weill, François-Xavier, Grimont, Patrick A. D., Brisse, Sylvain

Two blaOKP subgroups were found, diverging by 4.2%. Subgroups blaOKP-A (10 enzyme variants, pIs from 7.1 to 8.3) and blaOKP-B (11 variants, pI 7.1) showed similar antibiotic susceptibilities....

Multiple-Antibiotic Resistance in Salmonella enterica Serotype Paratyphi B Isolates Collected in France between 2000 and 2003 Is Due Mainly to Strains Harboring Salmonella Genomic Islands 1, 1-B, and 1-C

Weill, François-Xavier, Fabre, Laëtitia, Grandry, Bernadette, Grimont, Patrick A. D., Casin, Isabelle

This study was conducted to investigate the occurrence of multiple-antibiotic resistance among 261 clinical isolates of Salmonella enterica serotype Paratyphi B strains collected between 2000 and...

Multidrug Resistance in Salmonella enterica Serotype Typhimurium from Humans in France (1993 to 2003)

Weill, François-Xavier, Guesnier, Françoise, Guibert, Véronique, Timinouni, Mohammed, Demartin, Marie, Polomack, Lucette, ...

The aim of this study was to determine the distribution of the antimicrobial resistance phenotypes (R types), the phage types and XbaI-pulsed-field gel electrophoresis (PFGE) types, the genes coding...

Clonal Emergence of Extended-Spectrum β-Lactamase (CTX-M-2)-Producing Salmonella enterica Serovar Virchow Isolates with Reduced Susceptibilities to Ciprofloxacin among Poultry and Humans in Belgium and France (2000 to 2003)

Bertrand, Sophie, Weill, François-Xavier, Cloeckaert, Axel, Vrints, Martine, Mairiaux, Eric, Praud, Karine, ...

Antibiotic treatment is not required in cases of Salmonella enterica gastroenteritis but is essential in cases of enteric fever or invasive salmonellosis or in immunocompromised patients. Although...

Molecular and Phenotypic Characterization of Potentially New Shigella dysenteriae Serotype

Coimbra, Roney S., Lenormand, Pascal, Grimont, Francine, Bouvet, Philippe, Matsushita, Shigeru, Grimont, Patrick A. D.

From September 1997 to November 1998, the French National Center for Salmonella and Shigella received 22 Shigella isolates recovered from 22 different patients suffering from dysentery. None of these...

Clonal Relationships among Shigella Serotypes Suggested by Cryptic Flagellin Gene Polymorphism

Coimbra, Roney S., Lefevre, Martine, Grimont, Francine, Grimont, Patrick A. D.

The presence of cryptic fliC alleles in the genomes of 120 strains representative of the four Shigella species was investigated. One fragment was obtained by PCR amplification of fliC, with a size...

Restriction Fragment Length Polymorphism Analysis of Some Flagellin Genes of Salmonella enterica

Dauga, Catherine, Zabrovskaia, Anna, Grimont, Patrick A. D.

Salmonellae often have the ability to express two different flagellar antigen specificities (phase 1 and phase 2). At the cell level, only one flagellar phase is expressed at a time. Two genes, fliC,...

Genotypic Characteristics of Two Serotypes of Bartonella henselae

La Scola, Bernard, Liang, Zhongxing, Zeaiter, Zaher, Houpikian, Pierre, Grimont, Patrick A. D., Raoult, Didier

The study of 16S rRNA gene sequences of all isolates of Bartonella henselae obtained in our laboratory and others from human patients or cats has revealed two genotypes according to the sequence of...

Persistent Endemicity of Salmonella bongori 48:z35:− in Southern Italy: Molecular Characterization of Human, Animal, and Environmental Isolates

Giammanco, Giovanni M., Pignato, Sarina, Mammina, Caterina, Grimont, Francine, Grimont, Patrick A. D., Nastasi, Antonino, ...

From 1984 to 1999, we collected 31 isolates of the rare serovar Salmonella bongori 48:z35:− in southern Italy. Twenty-four of the isolates were from cases of acute enteritis in humans. Pulsed-field...

Identification of Major Streptococcal Species by rrn-Amplified Ribosomal DNA Restriction Analysis

Schlegel, Laurent, Grimont, Francine, Grimont, Patrick A. D., Bouvet, Anne

Amplified ribosomal DNA restriction analysis (rrn-ARDRA) is based on PCR amplification and restriction of a fragment of rRNA genes including 16S and 23S genes and the intergenic spacer. rrn-ARDRA was...

Genotypic and Phenotypic Characteristics of Corynebacterium diphtheriae Strains Isolated from Patients in Belarus during an Epidemic Period

Titov, Leonid, Kolodkina, Valentina, Dronina, Alina, Grimont, Francine, Grimont, Patrick A. D., Lejay-Collin, Monique, ...

One hundred two Corynebacterium diphtheriae strains (93 of the gravis biotype and nine of the mitis biotype) isolated from clinical cases during the Belarus diphtheria epidemic were characterized by...

Bacteremia Caused by Acinetobacter ursingii

Loubinoux, Julien, Mihaila-Amrouche, Liliana, Le Fleche, Anne, Pigne, Etienne, Huchon, Gerard, Grimont, Patrick A. D., ...

Acinetobacter ursingii has not been reported in infectious processes apart from its recent description as a new species. A bacteremia caused by A. ursingii in a patient with a pulmonary...

Characterization of Shiga Toxin-Producing Escherichia coli O157:H7 Isolated in Italy and in France

Giammanco, Giovanni M., Pignato, Sarina, Grimont, Francine, Grimont, Patrick A. D., Caprioli, Alfredo, Morabito, Stefano, ...

Twenty-one Escherichia coli O157:H7 strains isolated in northern Italy from sporadic cases of hemolytic-uremic syndrome and from cattle and food were characterized by virulence gene analysis,...

Pyrazines Responsible for the Potatolike Odor Produced by Some Serratia and Cedecea Strains

Gallois, Annie, Grimont, Patrick A. D.

The pyrazines responsible for the potatolike odor produced by some Serratia and Cedecea cultures were identified by gas-liquid chromatography (with flame ionization and thermoionic ionization...

SHV-12-Like Extended-Spectrum-β-Lactamase-Producing Strains of Salmonella enterica Serotypes Babelsberg and Enteritidis Isolated in France among Infants Adopted from Mali

Weill, François-Xavier, Demartin, Marie, Tandé, Didier, Espié, Emmanuelle, Rakotoarivony, Ignace, Grimont, Patrick A. D.

From December 2002 to June 2003, 14 cultures of Salmonella enterica serotype Babelsberg and 6 cultures of serotype Enteritidis, isolated in France from internationally adopted children, were...

Extended-Spectrum-β-Lactamase (TEM-52)-Producing Strains of Salmonella enterica of Various Serotypes Isolated in France

Weill, François-Xavier, Demartin, Marie, Fabre, Laëtitia, Grimont, Patrick A. D.

From 2002 to 2003, four isolates of Salmonella enterica serotypes Typhimurium, Enteritidis, Blockley, and Panama, isolated in France from patients with gastroenteritis, were found to produce...

Endemic, Epidemic Clone of Salmonella enterica Serovar Typhi Harboring a Single Multidrug-Resistant Plasmid in Vietnam between 1995 and 2002

Le, Thi Anh Hong, Lejay-Collin, Monique, Grimont, Patrick A. D., Hoang, Thuy Long, Nguyen, Thi Vinh, Grimont, Francine, ...

Salmonella enterica serovar Typhi strains resistant to ampicillin, chloramphenicol, tetracyclines, streptomycin, and cotrimoxazole, isolated from sporadic cases and minor outbreaks in Vietnam between...

Molecular Serotyping of Klebsiella Species Isolates by Restriction of the Amplified Capsular Antigen Gene Cluster

Brisse, Sylvain, Issenhuth-Jeanjean, Sylvie, Grimont, Patrick A. D.

The objective of the present work was to develop a molecular method that would enable determination of the capsular serotypes of Klebsiella isolates without the use of antiserum. PCR amplification of...

Emergence of Extended-Spectrum-β-Lactamase (CTX-M-9)-Producing Multiresistant Strains of Salmonella enterica Serotype Virchow in Poultry and Humans in France

Weill, François-Xavier, Lailler, Renaud, Praud, Karine, Kérouanton, Annaëlle, Fabre, Laëtitia, Brisabois, Anne, ...

During 2002 to 2003, eight Salmonella enterica serotype Virchow poultry and poultry product isolates from various sources (chicken farms, poultry slaughterhouse, or retail store) and one S. enterica...

Corynebacterium ulcerans in an Immunocompromised Patient with Diphtheria and Her Dog

Lartigue, Marie-Frédérique, Monnet, Xavier, Le Flèche, Anne, Grimont, Patrick A. D., Benet, Jean-Jacques, Durrbach, Antoine, ...

Corynebacterium ulcerans causes zoonotic infections, such as diphtheria and extrapharyngeal infections. We report here the first case of a diphtheria-like illness caused by C. ulcerans in France and...

Endocarditis Due to a New Rod-Shaped Neisseria sp.

Michaux-Charachon, Sylvie, Lavigne, Jean-Philippe, Le Flèche, Anne, Bouziges, Nicole, Sotto, Albert, Grimont, Patrick A. D.

We report the first case of pacemaker endocarditis due to a new rod-shaped Neisseria sp. isolated from blood culture. On the basis of rrs sequencing, the isolate was found to be most closely related...

Nosocomial Outbreak Caused by Salmonella enterica Serotype Livingstone Producing CTX-M-27 Extended-Spectrum β-Lactamase in a Neonatal Unit in Sousse, Tunisia

Bouallègue-Godet, Olfa, Salem, Youssef Ben, Fabre, Laëtitia, Demartin, Marie, Grimont, Patrick A. D., Mzoughi, Ridha, ...

In this study, we report an outbreak of Salmonella enterica serotype Livingstone resistant to extended-spectrum cephalosporins that occurred in a neonatal ward of the maternity department of Farhat...

Multiple-Antibiotic Resistance in Salmonella enterica Serotype Paratyphi B Isolates Collected in France between 2000 and 2003 Is Due Mainly to Strains Harboring Salmonella Genomic Islands 1, 1-B, and 1-C

Weill, François-Xavier, Fabre, Laëtitia, Grandry, Bernadette, Grimont, Patrick A. D., Casin, Isabelle

This study was conducted to investigate the occurrence of multiple-antibiotic resistance among 261 clinical isolates of Salmonella enterica serotype Paratyphi B strains collected between 2000 and...

Bacteremia Caused by an Undescribed Species of Janibacter

Loubinoux, Julien, Rio, Bernard, Mihaila, Liliana, Foïs, Elena, Le Fleche, Anne, Grimont, Patrick A. D., ...

A yellow-pigmented rod- to coccoid-shaped coryneform microorganism was isolated from the blood of a patient with acute myeloid leukemia. It was identified by 16S rRNA gene sequencing as a previously...

Six Groups of the OXY β-Lactamase Evolved over Millions of Years in Klebsiella oxytoca

Fevre, Cindy, Jbel, Mehdi, Passet, Virginie, Weill, François-Xavier, Grimont, Patrick A. D., Brisse, Sylvain

The diversity and evolution of the class A OXY β-lactamase from Klebsiella oxytoca were investigated and compared to housekeeping gene diversity. The entire blaOXY coding region was sequenced in 18...

Multilocus Sequence Typing of Klebsiella pneumoniae Nosocomial Isolates

Diancourt, Laure, Passet, Virginie, Verhoef, Jan, Grimont, Patrick A. D., Brisse, Sylvain

A multilocus sequence typing (MLST) scheme was developed for Klebsiella pneumoniae. Sequences of seven housekeeping genes were obtained for 67 K. pneumoniae strains, including 19 ceftazidime- and...

Variants of the Klebsiella pneumoniae OKP Chromosomal Beta-Lactamase Are Divided into Two Main Groups, OKP-A and OKP-B

Fevre, Cindy, Passet, Virginie, Weill, François-Xavier, Grimont, Patrick A. D., Brisse, Sylvain

Two blaOKP subgroups were found, diverging by 4.2%. Subgroups blaOKP-A (10 enzyme variants, pIs from 7.1 to 8.3) and blaOKP-B (11 variants, pI 7.1) showed similar antibiotic susceptibilities....

Multidrug Resistance in Salmonella enterica Serotype Typhimurium from Humans in France (1993 to 2003)

Weill, François-Xavier, Guesnier, Françoise, Guibert, Véronique, Timinouni, Mohammed, Demartin, Marie, Polomack, Lucette, ...

The aim of this study was to determine the distribution of the antimicrobial resistance phenotypes (R types), the phage types and XbaI-pulsed-field gel electrophoresis (PFGE) types, the genes coding...

Clonal Emergence of Extended-Spectrum β-Lactamase (CTX-M-2)-Producing Salmonella enterica Serovar Virchow Isolates with Reduced Susceptibilities to Ciprofloxacin among Poultry and Humans in Belgium and France (2000 to 2003)

Bertrand, Sophie, Weill, François-Xavier, Cloeckaert, Axel, Vrints, Martine, Mairiaux, Eric, Praud, Karine, ...

Antibiotic treatment is not required in cases of Salmonella enterica gastroenteritis but is essential in cases of enteric fever or invasive salmonellosis or in immunocompromised patients. Although...

Clonal Expansion and Microevolution of Quinolone-Resistant Salmonella enterica Serotype Typhi in Vietnam from 1996 to 2004▿

Le, Thi Anh Hong, Fabre, Laëtitia, Roumagnac, Philippe, Grimont, Patrick A. D., Scavizzi, Maurice R., Weill, François-Xavier

Salmonella enterica serotype Typhi clinical isolates (n = 91) resistant to nalidixic acid (Nalr) were collected from sporadic cases and minor outbreaks throughout Vietnam between 1996 and 2004. These...

Ceftriaxone-Resistant Salmonella enterica Serotype Newport, France

Egorova, Svetlana, Timinouni, Mohammed, Demartin, Marie, Granier, Sophie A., Whichard, Jean M., Sangal, Vartul, ...

The multidrug-resistant (MDR) Salmonella enterica serotype Newport strain that produces CMY-2 β-lactamase (Newport MDR-AmpC) was the source of sporadic cases and outbreaks in humans in France during...