Patrick G. Hogan

Hair loss and defective T- and B-cell function in mice lacking ORAI1 (2008)

Gwack, Yousang, Srikanth, Sonal, Oh-Hora, Masatsugu, Hogan, Patrick G., Lamperti, Edward D., Yamashita, Megumi, ...

ORAI1 is a pore subunit of the store-operated Ca(2+) release-activated Ca(2+) (CRAC) channel. To examine the physiological consequences of ORAI1 deficiency, we generated mice with targeted disruption...

Surface Construction from Planar Contours, (2002)

Hogan, Patrick G., Zyda, Michael J.

Many scientific and technical endeavors require the reconstruction of a three-dimensional solid from a collection of two-dimensional contours. One method for this reconstruction involves a procedure...

Surface Construction from Planar Contours. (2002)

Hogan, Patrick G.

Many scientific and technical endeavors require the reconstruction of a three-dimensional solid from a collection of two-dimensional contours. One method for this reconstruction involves a procedure...

Surface Reconstruction from Planar Contours, (2002)

Jones,Allan R., Hogan,Patrick G., Zyda,Michael J.

Many applications of computer graphics involve the display of a three-dimensional solid reconstructed from a sequence of two dimensional planar contours. Surface construction algorithms accomplish...

Histologic and immunohistochemical responses after aortic valve allografts in the rat (1998)

Green, Marjorie K., Walsh, Michael D., Dare, Anthony, Hogan, Patrick G., Zhao, Xiao-Ming, Frazer, Ian H., ...

Background. Human aortic valve allografts elicit a cellular and humoral immune response. It is not clear whether this is important in promoting valve damage. We investigated the changes in...

Histologic and immunohistochemical responses after aortic valve allografts in the rat (1998)

Green, Marjorie K., Walsh, Michael D., Dare, Anthony, Hogan, Patrick G., Zhao, Xiao-Ming, Frazer, Ian H., ...

Background. Human aortic valve allografts elicit a cellular and humoral immune response. It is not clear whether this is important in promoting valve damage. We investigated the changes in...

Selective inhibition of calcineurin-NFAT signaling by blocking protein–protein interaction with small organic molecules

Roehrl, Michael H. A., Kang, Sunghyun, Aramburu, José, Wagner, Gerhard, Rao, Anjana, Hogan, Patrick G.

Transient or reversible protein–protein interactions are commonly used to ensure efficient targeting of signaling enzymes to their cellular substrates. These interactions include direct binding to...

Selective inhibition of calcineurin-NFAT signaling by blocking protein–protein interaction with small organic molecules

Roehrl, Michael H. A., Kang, Sunghyun, Aramburu, José, Wagner, Gerhard, Rao, Anjana, Hogan, Patrick G.

Transient or reversible protein–protein interactions are commonly used to ensure efficient targeting of signaling enzymes to their cellular substrates. These interactions include direct binding to...

Surface construction from planar contours.

Hogan, Patrick G.

Available from National Technical Information Service, Springfield, Va.

Hair Loss and Defective T- and B-Cell Function in Mice Lacking ORAI1▿ †

Gwack, Yousang, Srikanth, Sonal, Oh-hora, Masatsugu, Hogan, Patrick G., Lamperti, Edward D., Yamashita, Megumi, ...

ORAI1 is a pore subunit of the store-operated Ca2+ release-activated Ca2+ (CRAC) channel. To examine the physiological consequences of ORAI1 deficiency, we generated mice with targeted disruption of...

Requirement for balanced Ca/NFAT signaling in hematopoietic and embryonic development

Müller, Martin R., Sasaki, Yoshiteru, Stevanovic, Irena, Lamperti, Edward D., Ghosh, Srimoyee, Sharma, Sonia, ...

NFAT transcription factors are highly phosphorylated proteins residing in the cytoplasm of resting cells. Upon dephosphorylation by the phosphatase calcineurin, NFAT proteins translocate to the...

Domain Architecture of the Regulators of Calcineurin (RCANs) and Identification of a Divergent RCAN in Yeast▿ †

Mehta, Sohum, Li, Huiming, Hogan, Patrick G., Cunningham, Kyle W.

Regulators of calcineurin (RCANs) in fungi and mammals have been shown to stimulate and inhibit calcineurin signaling in vivo through direct interactions with the catalytic subunit of the...