Anisimov, Sergey V, Christophersen, Nicolaj S, Correia, Ana S, Li, Jia-Yi, Brundin, Patrik
Abstract Background Human stem cells are viewed as a possible source of neurons for a cell-based therapy of neurodegenerative disorders, such as Parkinson's disease. Several protocols that generate...
Christophersen, Nicolaj S, Gronborg, Mette, Petersen, Thomas N, Fjord-Larsen, Lone, Jorgensen, Jesper R, Juliusson, Bengt, ...
Abstract is not available
Large stem cell grafts could lead to erroneous interpretations of behavioral results? (2007)
Christophersen, Nicolaj Stroyer, Brundin, Patrik
Abstract is not available
Anisimov, Sergey V, Christophersen, Nicolaj S, Correia, Ana S, Li, Jia-Yi, Brundin, Patrik
Abstract is not available
Cocaine- and amphetamine-regulated transcript is increased in Huntington disease. (2007)
Björkqvist, Maria, Leavitt, Blair R, Nielsen, Jörgen E, Landwehrmeyer, Bernhard, Ecker, Daniel, Mulder, Hindrik, ...
Abstract is not available
Loss of SNAP-25 and rabphilin 3a in sensory-motor cortex in Huntington's disease. (2007)
Smith, Ruben, Klein, Pontus, Koc-Schmitz, Yeliz, Waldvogel, Henry J, Faull, Richard L M, Brundin, Patrik, ...
Abstract is not available
Restorative cell therapy for Parkinson's disease: A quest for the perfect cell. (2007)
Hall, Vanessa J, Li, Jia-Yi, Brundin, Patrik
Abstract is not available
Increased metabolism in the R6/2 mouse model of Huntington's disease. (2007)
Bacos, Karl, Wood, Nigel I, Lindqvist, Andreas, Wierup, Nils, Woodman, Ben, ...
Abstract is not available
From bench to bed: the potential of stem cells for the treatment of Parkinson's disease. (2007)
Morizane, Asuka, Li, Jia-Yi, Brundin, Patrik
Abstract is not available
Failure of transdifferentiation of adult hematopoietic stem cells into neurons. (2006)
Roybon, Laurent, Ma, Zhi, Asztely, Fredrik, Fosum, Anna, Jacobsen, Sten Eirik W, Brundin, Patrik, ...
Abstract is not available
On the move to stimulate cell plasticity in the substantia nigra in Parkinson's disease. (2006)
Brundin, Patrik, Angela Cenci, M, Wieloch, Tadeusz
Abstract is not available.
Cholinergic neuronal defect without cell loss in Huntington's disease. (2006)
Smith, Ruben, Chung, Hinfan, Rundquist, Sara, Colgan, Lesley, Englund, Elisabet, ...
Abstract is not available
Westin, Jenny E, Lindgren, Hanna S, Gardi, Jonathan, Nyengaard, Jens Randel, Brundin, Patrik, Mohapel, Paul, ...
Abstract is not available
Transplantation in Parkinson's disease: The future looks bright. (2006)
Paul, Gesine, Ahn, Young Hwan, Li, Jia-Yi, Brundin, Patrik
Abstract is not available.
Nygren, Josefine, Wieloch, Tadeusz, Pesic, Jelena, Brundin, Patrik, Deierborg, Tomas
Abstract is not available
Christophersen, Nicolaj S, Meijer, Xia, Jørgensen, Jesper R, Englund, Ulrica, Grønborg, Mette, Seiger, Ake, ...
Abstract is not available
High-fat diet impairs hippocampal neurogenesis in male rats. (2006)
Lindqvist, A, Mohapel, P, Bouter, B, Frielingsdorf, Helena, Pizzo, D, Brundin, Patrik, ...
Abstract is not available
Van Der Borght, Karin, Brundin, Patrik
Abstract is not available
Björkqvist, Maria, Fex, Malin, Renström, Erik, Wierup, Nils, Petersén, Asa, Gil, Joana, ...
Abstract is not available
Proteolysis of NR2B by calpain in the hippocampus of epileptic rats. (2005)
Araújo, Inês, Xapelli, Sara, Gil, Joana, Mohapel, Paul, Petersén, Asa, Pinheiro, Paulo, ...
Abstract is not available
Popovic, Natalija, Maingay, Matthew, Kirik, Deniz, Brundin, Patrik
Abstract is not available
Smith, Ruben, Petersén, Asa, Bates, Gillian P, Brundin, Patrik, Li, Jia-Yi
Abstract is not available
Reduced hippocampal neurogenesis in R6/2 transgenic Huntington's disease mice. (2005)
Mohapel, Paul, Araújo, Inês M, Popovic, Natalija, Li, Jia-Yi, Brundin, Patrik, ...
Abstract is not available
Iancu, Ruxandra, Mohapel, Paul, Brundin, Patrik, Paul, Gesine
Abstract is not available
Ahn, Young-Hwan, Bensadoun, Jean-Charles, Aebischer, Patrick, Zurn, Anne D, Seiger, Ake, Björklund, Anders, ...
Abstract is not available
Karlsson, Jenny, Petersén, Asa, Gidö, Gunilla, Wieloch, Tadeusz, Brundin, Patrik
Abstract is not available
Roybon, Laurent, Brundin, Patrik, Li, Jia-Yi
Abstract is not available
Reduction of GnRH and infertility in the R6/2 mouse model of Huntington's disease. (2005)
Papalexi, Eugenia, Persson, Anna, Bjorkqvist, Maria, Petersén, Asa, Woodman, Ben, Bates, Gillian P, ...
Abstract is not available
Stem cell-based therapy for Parkinson's disease. (2005)
Correia, Ana Sofia, Anisimov, Sergey V, Li, Jia-Yi, Brundin, Patrik
Abstract is not available
Puschban, Zoe, Stefanova, Nadia, Petersén, Asa, Winkler, Christian, Brundin, Patrik, Poewe, Werner, ...
Abstract is not available
Li, Jia Yi, Popovic, Natalija, Brundin, Patrik
Abstract is not available
Asialoerythropoetin is not effective in the R6/2 line of Huntington's disease mice (2004)
Gil, Joana MAC, Leist, Marcel, Popovic, Natalija, Brundin, Patrik, Petersén, Åsa
Abstract Background Huntington's disease (HD) is a hereditary neurodegenerative disorder caused by an expanded CAG repeat in the HD gene. Both excitotoxicity and oxidative stress have been proposed...
No evidence for new dopaminergic neurons in the adult mammalian substantia nigra. (2004)
Frielingsdorf, Helena, Schwarz, Katherine, Brundin, Patrik, Mohapel, Paul
Abstract is not available
Harnessing endogenous stem cells to treat neurodegenerative disorders of the basal ganglia. (2004)
Mohapel, Paul, Brundin, Patrik
Abstract is not available
Stem cell therapy for Parkinson's disease: where do we stand? (2004)
Roybon, Laurent, Christophersen, Nicolaj S., Brundin, Patrik, Li, Jia-Yi
Abstract is not available
Orexin loss in Huntington's disease. (2004)
Petersén, Asa, Gil, Joana, Maat-Schieman, Marion Lc, Björkqvist, Maria, Tanila, Heikki, Araújo, Ines M, ...
Abstract is not available
Hansson, Oskar, Nylandsted, Jesper, Castilho, Roger F, Leist, Marcel, Jäättelä, Marja, Brundin, Patrik
Abstract is not available
Smith, Ruben, Lotharius, Julie, Brundin, Patrik
Abstract is not available
Ahn, Young Hwan, Emgård, Mia, Brundin, Patrik
Abstract is not available
Neural transplantation for the treatment of Parkinson's disease. (2003)
Björklund, Anders, Dunnett, Stephen B, Brundin, Patrik, Stoessl, A Jon, Freed, Curt R, Breeze, Robert E, ...
Abstract is not available
Huntington's disease: a synaptopathy? (2003)
Li, Jia Yi, Plomann, Markus, Brundin, Patrik
Abstract is not available
Zeron, Melinda M, Hansson, Oskar, Chen, Nansheng, Wellington, Cheryl L, Leavitt, Blair R, Brundin, Patrik, ...
Previous work suggests N-methyl-D-aspartate receptor (NMDAR) activation may be involved in degeneration of medium-sized spiny striatal neurons in Huntington's disease (HD). Here we show that these...
Stem cells: hype or hope? (2002)
Paul, Gesine, Li, Jia, Brundin, Patrik
Stem cells undergo self-renewal and differentiate into multiple lineages of mature cells. The identification of stem cells in diverse adult tissues and the findings that human embryonic stem cells...
Funding embryonic stem-cell research: will commerce counteract collaboration? (2002)
Abstract not available
Dyskinesias following neural transplantation in Parkinson's disease. (2002)
Hagell, Peter, Piccini, Paola, Björklund, Anders, Brundin, Patrik, Rehncrona, Stig, Widner, Håkan, ...
Severe dyskinesias during the 'off' phases (periods of increased Parkinson's disease (PD) disability) have been observed following intrastriatal transplantation of human embryonic mesencephalic...
Lotharius, Julie, Barg, Sebastian, Wiekop, Pia, Lundberg, Cecilia, Raymon, Heather K., Brundin, Patrik
Mutations in alpha-synuclein have been linked to rare, autosomal dominant forms of Parkinsons disease. Despite its ubiquitous expression, mutant alpha-synuclein primarily leads to the loss of...
Lotharius, Julie, Brundin, Patrik
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by the inability to initiate, execute and control movement. Neuropathologically, there is a striking loss of...
Karlsson, Jenny, Emgård, Mia, Brundin, Patrik
Abstract is not available
Pathogenesis of Parkinson's disease: dopamine, vesicles and alpha-synuclein. (2002)
Lotharius, Julie, Brundin, Patrik
Abstract is not available
Huntington's disease: the mystery unfolds? (2002)
Petersén, Asa, Brundin, Patrik
Abstract not available.
Developing Human Embryonic Stem Cells for Grafting in Parkinson's Disease (1998)
The project aims to differentiate human embryonic stem cells (hESCs) into dopaminergic neurons for use in neural grafting in Parkinson's disease (PD). During the first year we studied the survival...
Hansson, Oskar, Petersén, Åsa, Leist, Marcel, Nicotera, Pierluigi, Castilho, Roger F., Brundin, Patrik
Huntington’s disease (HD) is a hereditary neurodegenerative disorder presenting with chorea, dementia, and extensive striatal neuronal death. The mechanism through which the widely expressed mutant...
Asialoerythropoetin is not effective in the R6/2 line of Huntington's disease mice
Gil, Joana MAC, Leist, Marcel, Popovic, Natalija, Brundin, Patrik, Petersén, Åsa
No evidence for new dopaminergic neurons in the adult mammalian substantia nigra
Frielingsdorf, Helena, Schwarz, Katherine, Brundin, Patrik, Mohapel, Paul
A recent report by Zhao et al. [Zhao, M., Momma, S., Delfani, K., Carlen, M., Cassidy, R. M., Johansson, C. B., Brismar, H., Shupliakov, O., Frisen, J. & Janson, A. M. (2003) Proc. Natl. Acad. Sci....
Li, Jia Yi, Popovic, Natalija, Brundin, Patrik
Summary: Huntington's disease (HD) is a genetic neurodegenerative disorder. Since identification of the disease-causing gene in 1993, a number of genetically modified animal models of HD have been...
Hansson, Oskar, Petersén, Åsa, Leist, Marcel, Nicotera, Pierluigi, Castilho, Roger F., Brundin, Patrik
Huntington’s disease (HD) is a hereditary neurodegenerative disorder presenting with chorea, dementia, and extensive striatal neuronal death. The mechanism through which the widely expressed mutant...
Asialoerythropoetin is not effective in the R6/2 line of Huntington's disease mice
Gil, Joana MAC, Leist, Marcel, Popovic, Natalija, Brundin, Patrik, Petersén, Åsa
No evidence for new dopaminergic neurons in the adult mammalian substantia nigra
Frielingsdorf, Helena, Schwarz, Katherine, Brundin, Patrik, Mohapel, Paul
A recent report by Zhao et al. [Zhao, M., Momma, S., Delfani, K., Carlen, M., Cassidy, R. M., Johansson, C. B., Brismar, H., Shupliakov, O., Frisen, J. & Janson, A. M. (2003) Proc. Natl. Acad. Sci....
Li, Jia Yi, Popovic, Natalija, Brundin, Patrik
Summary: Huntington's disease (HD) is a genetic neurodegenerative disorder. Since identification of the disease-causing gene in 1993, a number of genetically modified animal models of HD have been...
Correia, Ana Sofia, Anisimov, Sergey V., Roybon, Laurent, Li, Jia-Yi, Brundin, Patrik
In the central nervous system, fibroblast growth factor (FGF)-20 has been reported to act preferentially on midbrain dopaminergic neurons. It also promotes the dopaminergic differentiation of stem...
Correia, Ana Sofia, Anisimov, Sergey V., Li, Jia-Yi, Brundin, Patrik
Human embryonic stem cells (hESCs) are a potential source of dopaminergic neurons for treatment of patients with Parkinson's disease (PD). Dopaminergic neurons can be derived from hESCs and display a...