Review of Archaea: Molecular and Cellular Biology (2008)
Archaea along with bacteria comprise the two groups of prokaryotes. The discovery of the Archaea, now over 30 years ago, has blossomed into fascinating revelations about the origin of life and the...
Szabó, Zalán, Sani, Musa, Groeneveld, Maarten, Zolghadr, Benham, Schelert, James, Albers, Sonja-Verena, ...
Flagellation in archaea is widespread and is involved in swimming motility. Here, we demonstrate that the structural flagellin gene from the crenarchaeaon Sulfolobus solfataricus is highly expressed...
Thesis (Ph. D.)--University of Notre Dame, May, 1976.
Coordinate Transcriptional Control in the Hyperthermophilic Archaeon Sulfolobus solfataricus
Haseltine, Cynthia, Montalvo-Rodriguez, Rafael, Bini, Elisabetta, Carl, Audrey, Blum, Paul
The existence of a global gene regulatory system in the hyperthermophilic archaeon Sulfolobus solfataricus is described. The system is responsive to carbon source quality and acts at the level of...
Secreted Euryarchaeal Microhalocins Kill Hyperthermophilic Crenarchaea
Haseltine, Cynthia, Hill, Tiffany, Montalvo-Rodriguez, Rafael, Kemper, Samantha K., Shand, Richard F., Blum, Paul
Few antibiotics targeting members of the archaeal domain are currently available for genetic studies. Since bacterial antibiotics are frequently directed against competing and related organisms,...
Rockabrand, David, Austin, Teresa, Kaiser, Robyn, Blum, Paul
Municipal effluent is the largest reservoir of human enteric bacteria. Its public health significance, however, depends upon the physiological status of the wastewater bacterial community. A novel...
Roles of DnaK and RpoS in Starvation-Induced Thermotolerance of Escherichia coli
Rockabrand, David, Livers, Kevin, Austin, Tess, Kaiser, Robyn, Jensen, Debra, Burgess, Richard, ...
DnaK is essential for starvation-induced resistance to heat, oxidation, and reductive division in Escherichia coli. Studies reported here indicate that DnaK is also required for starvation-induced...
Rolfsmeier, Michael, Haseltine, Cynthia, Bini, Elisabetta, Clark, Amy, Blum, Paul
Acidic hot springs are colonized by a diversity of hyperthermophilic organisms requiring extremes of temperature and pH for growth. To clarify how carbohydrates are consumed in such locations, the...
Targeted Disruption of the α-Amylase Gene in the Hyperthermophilic Archaeon Sulfolobus solfataricus
Worthington, Penny, Hoang, Viet, Perez-Pomares, Francisco, Blum, Paul
Sulfolobus solfataricus secretes an acid-resistant α-amylase (amyA) during growth on starch as the sole carbon and energy source. Synthesis of this activity is subject to catabolite repression. To...
Large-Scale Cultivation of Acidophilic Hyperthermophiles for Recovery of Secreted Proteins
Worthington, Penny, Blum, Paul, Perez-Pomares, Francisco, Elthon, Tom
An electric water heater was modified for large-scale cultivation of aerobic acidophilic hyperthermophiles to enable recovery of secreted proteins. Critical changes included thermostat replacement,...
Ponniah, Gomathinayagam, Chen, Han, Michielutti, Ronda, Salonen, Nancy, Blum, Paul
The efficiency of enterobacterial disinfection is dependent largely on enterobacterial community physiology. However, the relationship between enterobacterial community physiology and wastewater...
Schelert, James, Dixit, Vidula, Hoang, Viet, Simbahan, Jessica, Drozda, Melissa, Blum, Paul
Mercury resistance mediated by mercuric reductase (MerA) is widespread among bacteria and operates under the control of MerR. MerR represents a unique class of transcription factors that exert both...
Dixit, Vidula, Bini, Elisabetta, Drozda, Melissa, Blum, Paul
Mercury has a long history as an antimicrobial agent effective against eukaryotic and prokaryotic organisms. Despite its prolonged use, the basis for mercury toxicity in prokaryotes is not well...
A freestanding proofreading domain is required for protein synthesis quality control in Archaea
Korencic, Dragana, Ahel, Ivan, Schelert, James, Sacher, Meik, Ruan, Benfang, Stathopoulos, Constantinos, ...
Threonyl-tRNA synthetase (ThrRS) participates in protein synthesis quality control by selectively editing the misacylated species Ser-tRNAThr. In bacteria and eukaryotes the editing function of ThrRS...
Chen, Han, Ponniah, Gomathinayagam, Salonen, Nancy, Blum, Paul
A culture-independent method called mRNA profiling has been developed for the analysis of fecal enterobacteria and their physiological status in environmental samples. This taxon-specific approach...
Simbahan, Jessica, Kurth, Elizabeth, Schelert, James, Dillman, Amanda, Moriyama, Etsuko, Jovanovich, Stevan, ...
Mercury is a redox-active heavy metal that reacts with active thiols and depletes cellular antioxidants. Active resistance to the mercuric ion is a widely distributed trait among bacteria and results...
Stability of mRNA in the hyperthermophilic archaeon Sulfolobus solfataricus.
Bini, Elisabetta, Dikshit, Vidula, Dirksen, Kristi, Drozda, Melissa, Blum, Paul
Archaea-like bacteria are prokaryotes but, in contrast, use eukaryotic-like systems for key aspects of DNA, RNA, and protein metabolism. mRNA is typically unstable in bacteria and stable in...
Hoang, Viet, Bini, Elisabetta, Dixit, Vidula, Drozda, Melissa, Blum, Paul
The archaeon Sulfolobus solfataricus uses a catabolite repression-like system to control production of several glycoside hydrolases. To better understand this regulatory system, studies of the...
Coordinate Transcriptional Control in the Hyperthermophilic Archaeon Sulfolobus solfataricus
Haseltine, Cynthia, Montalvo-Rodriguez, Rafael, Bini, Elisabetta, Carl, Audrey, Blum, Paul
The existence of a global gene regulatory system in the hyperthermophilic archaeon Sulfolobus solfataricus is described. The system is responsive to carbon source quality and acts at the level of...
Secreted Euryarchaeal Microhalocins Kill Hyperthermophilic Crenarchaea
Haseltine, Cynthia, Hill, Tiffany, Montalvo-Rodriguez, Rafael, Kemper, Samantha K., Shand, Richard F., Blum, Paul
Few antibiotics targeting members of the archaeal domain are currently available for genetic studies. Since bacterial antibiotics are frequently directed against competing and related organisms,...
Rockabrand, David, Austin, Teresa, Kaiser, Robyn, Blum, Paul
Municipal effluent is the largest reservoir of human enteric bacteria. Its public health significance, however, depends upon the physiological status of the wastewater bacterial community. A novel...
Roles of DnaK and RpoS in Starvation-Induced Thermotolerance of Escherichia coli
Rockabrand, David, Livers, Kevin, Austin, Tess, Kaiser, Robyn, Jensen, Debra, Burgess, Richard, ...
DnaK is essential for starvation-induced resistance to heat, oxidation, and reductive division in Escherichia coli. Studies reported here indicate that DnaK is also required for starvation-induced...
Rolfsmeier, Michael, Haseltine, Cynthia, Bini, Elisabetta, Clark, Amy, Blum, Paul
Acidic hot springs are colonized by a diversity of hyperthermophilic organisms requiring extremes of temperature and pH for growth. To clarify how carbohydrates are consumed in such locations, the...
Targeted Disruption of the α-Amylase Gene in the Hyperthermophilic Archaeon Sulfolobus solfataricus
Worthington, Penny, Hoang, Viet, Perez-Pomares, Francisco, Blum, Paul
Sulfolobus solfataricus secretes an acid-resistant α-amylase (amyA) during growth on starch as the sole carbon and energy source. Synthesis of this activity is subject to catabolite repression. To...
Large-Scale Cultivation of Acidophilic Hyperthermophiles for Recovery of Secreted Proteins
Worthington, Penny, Blum, Paul, Perez-Pomares, Francisco, Elthon, Tom
An electric water heater was modified for large-scale cultivation of aerobic acidophilic hyperthermophiles to enable recovery of secreted proteins. Critical changes included thermostat replacement,...
Ponniah, Gomathinayagam, Chen, Han, Michielutti, Ronda, Salonen, Nancy, Blum, Paul
The efficiency of enterobacterial disinfection is dependent largely on enterobacterial community physiology. However, the relationship between enterobacterial community physiology and wastewater...
Schelert, James, Dixit, Vidula, Hoang, Viet, Simbahan, Jessica, Drozda, Melissa, Blum, Paul
Mercury resistance mediated by mercuric reductase (MerA) is widespread among bacteria and operates under the control of MerR. MerR represents a unique class of transcription factors that exert both...
Dixit, Vidula, Bini, Elisabetta, Drozda, Melissa, Blum, Paul
Mercury has a long history as an antimicrobial agent effective against eukaryotic and prokaryotic organisms. Despite its prolonged use, the basis for mercury toxicity in prokaryotes is not well...
A freestanding proofreading domain is required for protein synthesis quality control in Archaea
Korencic, Dragana, Ahel, Ivan, Schelert, James, Sacher, Meik, Ruan, Benfang, Stathopoulos, Constantinos, ...
Threonyl-tRNA synthetase (ThrRS) participates in protein synthesis quality control by selectively editing the misacylated species Ser-tRNAThr. In bacteria and eukaryotes the editing function of ThrRS...
Chen, Han, Ponniah, Gomathinayagam, Salonen, Nancy, Blum, Paul
A culture-independent method called mRNA profiling has been developed for the analysis of fecal enterobacteria and their physiological status in environmental samples. This taxon-specific approach...
Simbahan, Jessica, Kurth, Elizabeth, Schelert, James, Dillman, Amanda, Moriyama, Etsuko, Jovanovich, Stevan, ...
Mercury is a redox-active heavy metal that reacts with active thiols and depletes cellular antioxidants. Active resistance to the mercuric ion is a widely distributed trait among bacteria and results...
Stability of mRNA in the hyperthermophilic archaeon Sulfolobus solfataricus.
Bini, Elisabetta, Dikshit, Vidula, Dirksen, Kristi, Drozda, Melissa, Blum, Paul
Archaea-like bacteria are prokaryotes but, in contrast, use eukaryotic-like systems for key aspects of DNA, RNA, and protein metabolism. mRNA is typically unstable in bacteria and stable in...
Hoang, Viet, Bini, Elisabetta, Dixit, Vidula, Drozda, Melissa, Blum, Paul
The archaeon Sulfolobus solfataricus uses a catabolite repression-like system to control production of several glycoside hydrolases. To better understand this regulatory system, studies of the...
Regulation of Mercury Resistance in the Crenarchaeote Sulfolobus solfataricus†
Schelert, James, Drozda, Melissa, Dixit, Vidula, Dillman, Amanda, Blum, Paul
Mercuric ion, Hg(II), inactivates generalized transcription in the crenarchaeote Sulfolobus solfataricus. Metal challenge simultaneously derepresses transcription of mercuric reductase (merA) by...
Flagellar Motility and Structure in the Hyperthermoacidophilic Archaeon Sulfolobus solfataricus▿
Szabó, Zalán, Sani, Musa, Groeneveld, Maarten, Zolghadr, Benham, Schelert, James, Albers, Sonja-Verena, ...
Flagellation in archaea is widespread and is involved in swimming motility. Here, we demonstrate that the structural flagellin gene from the crenarchaeaon Sulfolobus solfataricus is highly expressed...
Characterization of different crystal forms of the α-glucosidase MalA from Sulfolobus solfataricus
Ernst, Heidi Asschenfeldt, Willemoës, Martin, Lo Leggio, Leila, Leonard, Gordon, Blum, Paul, Larsen, Sine
Crystallization of the α-glucosidase MalA from S. solfataricus belonging to glycoside hydrolase family 31.
Maaty, Walid S., Wiedenheft, Blake, Tarlykov, Pavel, Schaff, Nathan, Heinemann, Joshua, Robison-Cox, Jim, ...
To avoid molecular damage of biomolecules due to oxidation, all cells have evolved constitutive and responsive systems to mitigate and repair chemical modifications. Archaea have adapted to some of...