Scholler, Nathalie, Gross, Jennifer A, Garvik, Barbara, Wells, Lance, Liu, Yan, Loch, Christian M, ...
Abstract Background Strategies to discover circulating protein markers of ovarian cancer are urgently needed. We developed a novel technology that permits us to isolate recombinant antibodies...
A Cautionary Note on the Evaluation of Biomarkers of Subtypes of a Single Disease (2008)
Adewale, Adeniyi J., Liu, Qi, Dinu, Irina, Lampe, Paul D., Mitchell, Bree L., Yasui, Yutaka
Heterogeneity in the molecular characteristics of a disease presents a challenge to investigators attempting to identify biomarkers of the disease. Preceding the biomarker discovery effort with...
Impact of Freeze-thaw Cycles and Storage Time on Plasma (2005)
Breeana L Mitchell, Yutaka Yasui, Christopher I Li, Annette L. Fitzpatrick, Paul D Lampe
Abstract: Mass spectrometry approaches to biomarker discovery in human fluids have received a great deal of attention in recent years. While mass spectrometry instrumentation and analysis approaches...
Breeana L Mitchell, Yutaka Yasui, Christopher I Li, Annette L. Fitzpatrick, Paul D Lampe
Abstract: Mass spectrometry approaches to biomarker discovery in human fluids have received a great deal of attention in recent years. While mass spectrometry instrumentation and analysis approaches...
King, Timothy J., Lampe, Paul D.
Loss of connexin expression/gap junction intercellular communication (GJIC) has been correlated with decreased growth control and increased tumorigenesis. Studies utilizing Connexin32...
King, Timothy J., Lampe, Paul D.
Loss of connexin expression/gap junction intercellular communication (GJIC) has been correlated with decreased growth control and increased tumorigenesis. Studies utilizing Connexin32...
Chu, Guoxiang, Carr, Andrew N., Young, Karen B., Lester, J.William, Yatani, Atsuko, Sanbe, Atsushi, ...
Objective: Impaired myocyte Ca2+ handling is a common characteristic of failing hearts and increases in calcineurin activity, a Ca2+-sensitive phosphatase, have been implicated in heart failure...
Bukauskas, Feliksas F., Jordan, Karen, Bukauskiene, Angele, Bennett, Michael V. L., Lampe, Paul D., Laird, Dale W., ...
Communication-incompetent cell lines were transfected with connexin (Cx) 43 fused with enhanced green fluorescent protein (EGFP) to examine the relation between Cx distribution determined by...
Jordan, Karen, Solan, Joell L., Dominguez, Michel, Sia, Michael, Hand, Art, Lampe, Paul D., ...
To examine the trafficking, assembly, and turnover of connexin43 (Cx43) in living cells, we used an enhanced red-shifted mutant of green fluorescent protein (GFP) to construct a Cx43-GFP chimera....
Bukauskas, Feliksas F., Jordan, Karen, Bukauskiene, Angele, Bennett, Michael V. L., Lampe, Paul D., Laird, Dale W., ...
Communication-incompetent cell lines were transfected with connexin (Cx) 43 fused with enhanced green fluorescent protein (EGFP) to examine the relation between Cx distribution determined by...
Jordan, Karen, Solan, Joell L., Dominguez, Michel, Sia, Michael, Hand, Art, Lampe, Paul D., ...
To examine the trafficking, assembly, and turnover of connexin43 (Cx43) in living cells, we used an enhanced red-shifted mutant of green fluorescent protein (GFP) to construct a Cx43-GFP chimera....
Richards, Theresa S., Dunn, Clarence A., Carter, William G., Usui, Marcia L., Olerud, John E., Lampe, Paul D.
Phosphorylation of connexin43 (Cx43) on serine368 (S368) has been shown to decrease gap junctional communication via a reduction in unitary channel conductance. Examination of phosphoserine368...
Cellular Interaction of Integrin α3β1 with Laminin 5 Promotes Gap Junctional Communication
Lampe, Paul D., Nguyen, Beth P., Gil, Susana, Usui, Marcia, Olerud, John, Takada, Yoshikazu, ...
Wounding of skin activates epidermal cell migration over exposed dermal collagen and fibronectin and over laminin 5 secreted into the provisional basement membrane. Gap junctional intercellular...
Lampe, Paul D., TenBroek, Erica M., Burt, Janis M., Kurata, Wendy E., Johnson, Ross G., Lau, Alan F.
Phorbol esters (e.g., TPA) activate protein kinase C (PKC), increase connexin43 (Cx43) phosphorylation, and decrease cell–cell communication via gap junctions in many cell types. We asked whether...
Ser364 of connexin43 and the upregulation of gap junction assembly by cAMP
TenBroek, Erica M., Lampe, Paul D., Solan, Joell L., Reynhout, James K., Johnson, Ross G.
The assembly of gap junctions (GJs) is a process coordinated by growth factors, kinases, and other signaling molecules. GJ assembly can be enhanced via the elevation of cAMP and subsequent...
Solan, Joell L., Marquez-Rosado, Lucrecia, Sorgen, Paul L., Thornton, Perry J., Gafken, Philip R., Lampe, Paul D.
Phosphorylation at unspecified sites is known to regulate the life cycle (assembly, gating, and turnover) of the gap junction protein, Cx43. In this paper, we show that Cx43 is phosphorylated on S365...
Kalcheva, Nellie, Qu, Jiaxiang, Sandeep, Nefthi, Garcia, Luis, Zhang, Jie, Wang, Zhiyong, ...
Gap junction channels are required for normal cardiac impulse propagation, and gap junction remodeling is associated with enhanced arrhythmic risk. Oculodentodigital dysplasia (ODDD) is a multisystem...
Scholler, Nathalie, Gross, Jennifer A, Garvik, Barbara, Wells, Lance, Liu, Yan, Loch, Christian M, ...
Mitchell, Breeana L, Yasui, Yutaka, Li, Christopher I, Fitzpatrick, Annette L., Lampe, Paul D
Mass spectrometry approaches to biomarker discovery in human fluids have received a great deal of attention in recent years. While mass spectrometry instrumentation and analysis approaches have been...