Robustness promotes evolvability of thermotolerance in an RNA virus (2008)
McBride, Robert C, Ogbunugafor, C Brandon, Turner, Paul E
Abstract Background The ability for an evolving population to adapt to a novel environment is achieved through a balance of robustness and evolvability. Robustness is the invariance of phenotype in...
Evolutionary Genomics of Host Adaptation in Vesicular Stomatitis Virus (2008)
Remold, Susanna K., Rambaut, Andrew, Turner, Paul E.
Populations experiencing similar selection pressures can sometimes diverge in the genetic architectures underlying evolved complex traits. We used RNA virus populations of large size and high...
Evolution of Mutational Robustness in an RNA Virus (2005)
Rebecca Montville, Remy Froissart, Susanna K. Remold, Olivier Tenaillon, Paul E. Turner
RNA phage viruses evolved under high co-infection of host cells are less robust to mutations than those propagated under low co-infection, suggesting that co-infection may be advantageous to RNA...
Evolution of Mutational Robustness in an RNA Virus (2005)
Rebecca Montville, Remy Froissart, Susanna K. Remold, Olivier Tenaillon, Paul E. Turner
Mutational (genetic) robustness is phenotypic constancy in the face of mutational changes to the genome. Robustness is critical to the understanding of evolution because phenotypically expressed...
The relationship between risk for drug abuse and meaning in life / (1995)
Thesis (M.S.)--Western Kentucky University, 1995.
Typescript.
Hybrid Frequencies Confirm Limit to Coinfection in the RNA Bacteriophage φ6
Turner, Paul E., Burch, Christina L., Hanley, Kathryn A., Chao, Lin
Coinfection of the same host cell by multiple viruses may lead to increased competition for limited cellular resources, thus reducing the fitness of an individual virus. Selection should favor...
Evolution of Mutational Robustness in an RNA Virus
Montville, Rebecca, Froissart, Remy, Remold, Susanna K, Tenaillon, Olivier, Turner, Paul E
Mutational (genetic) robustness is phenotypic constancy in the face of mutational changes to the genome. Robustness is critical to the understanding of evolution because phenotypically expressed...
Dennehy, John J., Friedenberg, Nicholas A., Yang, Yul W., Turner, Paul E.
Pathogens vectored by nematodes pose serious agricultural, economic, and health threats; however, little is known of the ecological and evolutionary aspects of pathogen transmission by nematodes....
Widespread genetic exchange among terrestrial bacteriophages
Silander, Olin K., Weinreich, Daniel M., Wright, Kevin M., O'Keefe, Kara J., Rang, Camilla U., Turner, Paul E., ...
Bacteriophages are the most numerous entities in the biosphere. Despite this numerical dominance, the genetic structure of bacteriophage populations is poorly understood. Here, we present a...
Co-infection Weakens Selection Against Epistatic Mutations in RNA Viruses
Froissart, Rémy, Wilke, Claus O., Montville, Rebecca, Remold, Susanna K., Chao, Lin, Turner, Paul E.
Co-infection may be beneficial in large populations of viruses because it permits sexual exchange between viruses that is useful in combating the mutational load. This advantage of sex should be...
Pleiotropic Costs of Niche Expansion in the RNA Bacteriophage Φ6
Duffy, Siobain, Turner, Paul E., Burch, Christina L.
Natural and experimental systems have failed to universally demonstrate a trade-off between generalism and specialism. When a trade-off does occur it is difficult to attribute its cause to...
Phenotypic plasticity in bacterial plasmids.
Plasmid pB15 was previously shown to evolve increased horizontal (infectious) transfer at the expense of reduced vertical (intergenerational) transfer and vice versa, a key trade-off assumed in...
Hybrid Frequencies Confirm Limit to Coinfection in the RNA Bacteriophage φ6
Turner, Paul E., Burch, Christina L., Hanley, Kathryn A., Chao, Lin
Coinfection of the same host cell by multiple viruses may lead to increased competition for limited cellular resources, thus reducing the fitness of an individual virus. Selection should favor...
Evolution of Mutational Robustness in an RNA Virus
Montville, Rebecca, Froissart, Remy, Remold, Susanna K, Tenaillon, Olivier, Turner, Paul E
Mutational (genetic) robustness is phenotypic constancy in the face of mutational changes to the genome. Robustness is critical to the understanding of evolution because phenotypically expressed...
Widespread genetic exchange among terrestrial bacteriophages
Silander, Olin K., Weinreich, Daniel M., Wright, Kevin M., O'Keefe, Kara J., Rang, Camilla U., Turner, Paul E., ...
Bacteriophages are the most numerous entities in the biosphere. Despite this numerical dominance, the genetic structure of bacteriophage populations is poorly understood. Here, we present a...
Dennehy, John J., Friedenberg, Nicholas A., Yang, Yul W., Turner, Paul E.
Pathogens vectored by nematodes pose serious agricultural, economic, and health threats; however, little is known of the ecological and evolutionary aspects of pathogen transmission by nematodes....
Co-infection Weakens Selection Against Epistatic Mutations in RNA Viruses
Froissart, Rémy, Wilke, Claus O., Montville, Rebecca, Remold, Susanna K., Chao, Lin, Turner, Paul E.
Co-infection may be beneficial in large populations of viruses because it permits sexual exchange between viruses that is useful in combating the mutational load. This advantage of sex should be...
Pleiotropic Costs of Niche Expansion in the RNA Bacteriophage Φ6
Duffy, Siobain, Turner, Paul E., Burch, Christina L.
Natural and experimental systems have failed to universally demonstrate a trade-off between generalism and specialism. When a trade-off does occur it is difficult to attribute its cause to...
Phenotypic plasticity in bacterial plasmids.
Plasmid pB15 was previously shown to evolve increased horizontal (infectious) transfer at the expense of reduced vertical (intergenerational) transfer and vice versa, a key trade-off assumed in...
Reduced fecundity is the cost of cheating in RNA virus phi6.
Dennehy, John J, Turner, Paul E
Co-infection by multiple viruses affords opportunities for the evolution of cheating strategies to use intracellular resources. Cheating may be costly, however, when viruses infect cells alone. We...