Paul G. Hitchen

Towards understanding the functional role of the glycosyltransferases involved in the biosynthesis of Moraxella catarrhalis lipooligosaccharide (2007)

Peak, Ian, Grice, Darren, Faglin, Isabelle, Klipic, Zoran, Collins, Patrick, Van Schendel, Lucien, ...

Yes

The immunologically distinct O antigens from Francisella tularensis subspecies tularensis and Francisella novicida are both virulence determinants and protective antigens (2007)

Thomas, Rebecca R, Titball, Richard, Oyston, Petra C. F., Griffin, Kate, Waters, Emma, Hitchen, Paul G, ...

Yes

Towards understanding the functional role of the glycosyltransferases involved in the biosynthesis of Moraxella catarrhalis lipooligosaccharide (2007)

Peak, Ian, Grice, Darren, Faglin, Isabelle, Klipic, Zoran, Collins, Patrick, Van Schendel, Lucien, ...

The immunologically distinct O antigens from Francisella tularensis subspecies tularensis and Francisella novicida are both virulence determinants and protective antigens (2007)

Thomas, Rebecca R, Titball, Richard, Oyston, Petra C. F., Griffin, Kate, Waters, Emma, Hitchen, Paul G, ...

Identification of a capsular polysaccharide from moraxella bovis (2005)

Wilson, Jenny, Hitchen, Paul G, Frank, Martin, Peak, Ian, Collins, Patrick, Morris, Howard R., ...

The bacterium Moraxella bovis is the causative agent of an economically important disease of cattle: Infectious Bovine Keratoconjunctivitis (IBK), otherwise known as pinkeye. Little is known...

Identification of a capsular polysaccharide from moraxella bovis (2005)

Wilson, Jenny, Hitchen, Paul G, Frank, Martin, Peak, Ian, Collins, Patrick, Morris, Howard R., ...

The bacterium Moraxella bovis is the causative agent of an economically important disease of cattle: Infectious Bovine Keratoconjunctivitis (IBK), otherwise known as pinkeye. Little is known...

Identification of a capsular polysaccharide from moraxella bovis (2005)

Wilson, Jenny, Hitchen, Paul G, Frank, Martin, Peak, Ian, Collins, Patrick, Morris, Howard R., ...

The bacterium Moraxella bovis is the causative agent of an economically important disease of cattle: Infectious Bovine Keratoconjunctivitis (IBK), otherwise known as pinkeye. Little is known...

Unique modifications with phosphocholine and phosphoethanolamine define alternate antigenic forms of Neisseria gonorrhoeae type IV pili

Hegge, Finn Terje, Hitchen, Paul G., Aas, Finn Erik, Kristiansen, Heidi, Løvold, Cecilia, Egge-Jacobsen, Wolfgang, ...

Several major bacterial pathogens and related commensal species colonizing the human mucosa express phosphocholine (PC) at their cell surfaces. PC appears to impact host–microbe biology by serving...

Engineering N-linked protein glycosylation with diverse O antigen lipopolysaccharide structures in Escherichia coli

Feldman, Mario F., Wacker, Michael, Hernandez, Marcela, Hitchen, Paul G., Marolda, Cristina L., Kowarik, Michael, ...

Campylobacter jejuni has a general N-linked protein glycosylation system that can be functionally transferred to Escherichia coli. In this study, we engineered E. coli cells in a way that two...

Characterization of a putative alpha-mannosyltransferase involved in phosphatidylinositol trimannoside biosynthesis in Mycobacterium tuberculosis.

Kremer, Laurent, Gurcha, Sudagar S, Bifani, Pablo, Hitchen, Paul G, Baulard, Alain, Morris, Howard R, ...

Phosphatidyl-myo-inositol mannosides (PIMs), lipomannan (LM) and lipoarabinomannan (LAM) are an important class of bacterial factors termed modulins that are found in tuberculosis and leprosy....

Unique modifications with phosphocholine and phosphoethanolamine define alternate antigenic forms of Neisseria gonorrhoeae type IV pili

Hegge, Finn Terje, Hitchen, Paul G., Aas, Finn Erik, Kristiansen, Heidi, Løvold, Cecilia, Egge-Jacobsen, Wolfgang, ...

Several major bacterial pathogens and related commensal species colonizing the human mucosa express phosphocholine (PC) at their cell surfaces. PC appears to impact host–microbe biology by serving...

Engineering N-linked protein glycosylation with diverse O antigen lipopolysaccharide structures in Escherichia coli

Feldman, Mario F., Wacker, Michael, Hernandez, Marcela, Hitchen, Paul G., Marolda, Cristina L., Kowarik, Michael, ...

Campylobacter jejuni has a general N-linked protein glycosylation system that can be functionally transferred to Escherichia coli. In this study, we engineered E. coli cells in a way that two...

Characterization of a putative alpha-mannosyltransferase involved in phosphatidylinositol trimannoside biosynthesis in Mycobacterium tuberculosis.

Kremer, Laurent, Gurcha, Sudagar S, Bifani, Pablo, Hitchen, Paul G, Baulard, Alain, Morris, Howard R, ...

Phosphatidyl-myo-inositol mannosides (PIMs), lipomannan (LM) and lipoarabinomannan (LAM) are an important class of bacterial factors termed modulins that are found in tuberculosis and leprosy....

The Immunologically Distinct O Antigens from Francisella tularensis Subspecies tularensis and Francisella novicida Are both Virulence Determinants and Protective Antigens▿

Thomas, Rebecca M., Titball, Richard W., Oyston, Petra C. F., Griffin, Kate, Waters, Emma, Hitchen, Paul G., ...

We have determined the sequence of the gene cluster encoding the O antigen in Francisella novicida and compared it to the previously reported O-antigen cluster in Francisella tularensis subsp....

Structural characterization and functional properties of a novel lipomannan variant isolated from a Corynebacterium glutamicum pimB′ mutant

Mishra, Arun K., Klein, Christina, Gurcha, Sudagar S., Alderwick, Luke J., Babu, Ponnusamy, Hitchen, Paul G., ...

The genus Corynebacterium is part of the phylogenetic group nocardioform actinomycetes, which also includes the genus Mycobacterium. Members of this phylogenetic group have a characteristic cell...

Identification of AglE, a Second Glycosyltransferase Involved in N Glycosylation of the Haloferax volcanii S-Layer Glycoprotein▿

Abu-Qarn, Mehtap, Giordano, Assunta, Battaglia, Francesca, Trauner, Andrej, Hitchen, Paul G., Morris, Howard R., ...

Archaea, like Eukarya and Bacteria, are able to N glycosylate select protein targets. However, in contrast to relatively advanced understanding of the eukaryal N glycosylation process and the...