Marcelo A. Wood, Michelle A. Attner, Paul K. Brindle, Ted Abel, Email Alerting, ...
A transcription factor-binding domain of the coactivator CBP is essential for long-term memory and the expression of specific target genes
Wood, Marcelo A., Attner, Michelle A., Oliveira, Ana M.M., Brindle, Paul K., Abel, Ted
Transcriptional activation is a key process required for long-term memory formation. Recently, the transcriptional coactivator CREB-binding protein (CBP) was shown to be critical for...
Wood, Marcelo A., Attner, Michelle A., Oliveira, Ana M.M., Brindle, Paul K., Abel, Ted
Transcriptional activation is a key process required for long-term memory formation. Recently, the transcriptional coactivator CREB-binding protein (CBP) was shown to be critical for...
Lawryn H. Kasper, Tomofusa Fukuyama, Michelle A. Biesen, Fayçal Boussouar, Caili Tong, Antoine De Pauw, ...
The global transcriptional coactivators CREB-binding protein (CBP) and the closely related p300 interact with over 312 proteins, making them among the most heavily connected hubs in the known...
Kasper, Lawryn H., Brindle, Paul K., Schnabel, Catherine A., Pritchard, Colin E. J., Cleary, Michael L.
Genes encoding the Phe-Gly (FG) repeat-containing nucleoporins NUP98 and CAN/NUP214 are at the breakpoints of several chromosomal translocations associated with human acute myeloid leukemia (AML),...
Role of Secondary Structure in Discrimination between Constitutive and Inducible Activators
Parker, David, Rivera, Morris, Zor, Tsaffir, Henrion-Caude, Alexandra, Radhakrishnan, Ishwar, Kumar, Alok, ...
We have examined structural differences between the proto-oncogene c-Myb and the cyclic AMP-responsive factor CREB that underlie their constitutive or signal-dependent activation properties. Both...
Yang, Cheng, Shapiro, Linda H., Rivera, Morris, Kumar, Alok, Brindle, Paul K.
The Ets-1 transcription factor plays a critical role in cell growth and development, but the means by which it activates transcription are still unclear (J. C. Bories, D. M. Willerford, D. Grevin, L....
Nakajima, Hideaki, Brindle, Paul K., Handa, Makoto, Ihle, James N.
Signal transducers and activators of transcription (STATs) play a central role in cytokine signaling. Activating and repressing gene transcription is a dynamic process involving chromatin remodeling...
Kasper, Lawryn H., Fukuyama, Tomofusa, Biesen, Michelle A., Boussouar, Fayçal, Tong, Caili, De Pauw, Antoine, ...
The global transcriptional coactivators CREB-binding protein (CBP) and the closely related p300 interact with over 312 proteins, making them among the most heavily connected hubs in the known...
Two transactivation mechanisms cooperate for the bulk of HIF-1-responsive gene expression
Kasper, Lawryn H, Boussouar, Fayçal, Boyd, Kelli, Xu, Wu, Biesen, Michelle, Rehg, Jerold, ...
The C-terminal activation domain (C-TAD) of the hypoxia-inducible transcription factors HIF-1α and HIF-2α binds the CH1 domains of the related transcriptional coactivators CREB-binding protein...
Kasper, Lawryn H., Brindle, Paul K., Schnabel, Catherine A., Pritchard, Colin E. J., Cleary, Michael L.
Genes encoding the Phe-Gly (FG) repeat-containing nucleoporins NUP98 and CAN/NUP214 are at the breakpoints of several chromosomal translocations associated with human acute myeloid leukemia (AML),...
Role of Secondary Structure in Discrimination between Constitutive and Inducible Activators
Parker, David, Rivera, Morris, Zor, Tsaffir, Henrion-Caude, Alexandra, Radhakrishnan, Ishwar, Kumar, Alok, ...
We have examined structural differences between the proto-oncogene c-Myb and the cyclic AMP-responsive factor CREB that underlie their constitutive or signal-dependent activation properties. Both...
Yang, Cheng, Shapiro, Linda H., Rivera, Morris, Kumar, Alok, Brindle, Paul K.
The Ets-1 transcription factor plays a critical role in cell growth and development, but the means by which it activates transcription are still unclear (J. C. Bories, D. M. Willerford, D. Grevin, L....
Nakajima, Hideaki, Brindle, Paul K., Handa, Makoto, Ihle, James N.
Signal transducers and activators of transcription (STATs) play a central role in cytokine signaling. Activating and repressing gene transcription is a dynamic process involving chromatin remodeling...
Two transactivation mechanisms cooperate for the bulk of HIF-1-responsive gene expression
Kasper, Lawryn H, Boussouar, Fayçal, Boyd, Kelli, Xu, Wu, Biesen, Michelle, Rehg, Jerold, ...
The C-terminal activation domain (C-TAD) of the hypoxia-inducible transcription factors HIF-1α and HIF-2α binds the CH1 domains of the related transcriptional coactivators CREB-binding protein...
Kasper, Lawryn H., Fukuyama, Tomofusa, Biesen, Michelle A., Boussouar, Fayçal, Tong, Caili, De Pauw, Antoine, ...
The global transcriptional coactivators CREB-binding protein (CBP) and the closely related p300 interact with over 312 proteins, making them among the most heavily connected hubs in the known...
Xu, Wu, Fukuyama, Tomofusa, Ney, Paul A., Wang, Demin, Rehg, Jerold, Boyd, Kelli, ...
CREB-binding protein (CBP) and its para-log p300 are transcriptional coactivators that physically or functionally interact with over 320 mammalian and viral proteins, including 36 that are essential...
Wood, Marcelo A., Attner, Michelle A., Oliveira, Ana M.M., Brindle, Paul K., Abel, Ted
Transcriptional activation is a key process required for long-term memory formation. Recently, the transcriptional coactivator CREB-binding protein (CBP) was shown to be critical for...
Individual CREB-target genes dictate usage of distinct cAMP-responsive coactivation mechanisms
Xu, Wu, Kasper, Lawryn H, Lerach, Stephanie, Jeevan, Trushar, Brindle, Paul K
CREB is a key mediator of cAMP- and calcium-inducible transcription, where phosphorylation of serine 133 in its Kinase-Inducible Domain (KID) is often equated with transactivation. Phospho-Ser133 is...