Recombinant expression of Aryl Hydrocarbon Receptor for quantitative ligand-binding analysis (2009)
Fan, MingQi, Bell, Alex R, Bell, David Robert, Clode, Sally, Fernandes, Alwyn, Foster, Paul M D, ...
Recombinant expression of the Aryl Hydrocarbon Receptor (AhR) yields small amounts of ligand- binding competent AhR. Therefore, Spodoptera frugiperda (Sf9) cells and baculovirus have been evaluated...
Recombinant expression of Aryl Hydrocarbon Receptor for quantitative ligand-binding analysis (2009)
Fan, MingQi, Bell, Alex R, Bell, David Robert, Clode, Sally, Fernandes, Alwyn, Foster, Paul M D, ...
Recombinant expression of the Aryl Hydrocarbon Receptor (AhR) yields small amounts of ligand- binding competent AhR. Therefore, Spodoptera frugiperda (Sf9) cells and baculovirus have been evaluated...
Report for Food Standards Agency Project T01034: Risk assessment of dietary dioxins (2009)
Bell, David Robert, Clode, Sally, Fan, MingQi, Fernandes, Alwyn, Foster, Paul M D, Jiang, Tao, ...
These studies show conclusively that developmental exposure to TCDD during pregnancy did not cause potent effects on sperm levels in the offspring, nor cause potent effects on the weight of accessory...
Report for Food Standards Agency Project T01034: Risk assessment of dietary dioxins (2009)
Bell, David Robert, Clode, Sally, Fan, MingQi, Fernandes, Alwyn, Foster, Paul M D, Jiang, Tao, ...
These studies show conclusively that developmental exposure to TCDD during pregnancy did not cause potent effects on sperm levels in the offspring, nor cause potent effects on the weight of accessory...
Jiang, Tao, Bell, David R., Clode, Sally, Fan, Ming Qi, Fernandes, Alwyn, Foster, Paul M. D., ...
The aryl hydrocarbon receptor (AhR) is required for the toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), and so the AhR of CRL:WI and CRL:WI(Han) rats was characterized. Western blot showed...
Bell, David Robert, Clode, Sally, Fan, MingQi, Fernandes, Alwyn, Foster, Paul M D, Jiang, Tao, ...
We compared the effects of a single acute dose, or chronic fetal exposure, to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the male reproductive system of the Wistar(Han) rat. Tissue samples were...
Bell, David Robert, Clode, Sally, Fan, MingQi, Fernandes, Alwyn, Foster, Paul M D, Jiang, Tao, ...
We compared the effects of a single acute dose, or chronic fetal exposure, to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the male reproductive system of the Wistar(Han) rat. Tissue samples were...
Bell, David R., Clode, Sally, Fan, Ming Qi, Fernandes, Alwyn, Foster, Paul M. D., Jiang, Tao, ...
We compared the effects of a single acute dose, or chronic fetal exposure, to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the male reproductive system of the Wistar(Han) rat. Tissue samples were...
Bell, David Robert, Clode, Sally, Fan, MingQi, Fernandes, Alwyn, Foster, Paul M D, Jiang, Tao, ...
It has been reported that fetal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) causes defects in the male reproductive system of the rat. We set out to replicate and extend these effects...
Bell, David Robert, Clode, Sally, Fan, MingQi, Fernandes, Alwyn, Foster, Paul M D, Jiang, Tao, ...
It has been reported that fetal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) causes defects in the male reproductive system of the rat. We set out to replicate and extend these effects...
Bell, David R., Clode, Sally, Fan, Ming Qi, Fernandes, Alwyn, Foster, Paul M. D., Jiang, Tao, ...
We have investigated whether fetal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) causes defects in the male reproductive system of the rat using chronically exposed rats to ensure continuous...
Bell, David R., Clode, Sally, Fan, Ming Qi, Fernandes, Alwyn, Foster, Paul M. D., Jiang, Tao, ...
It has been reported that fetal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) causes defects in the male reproductive system of the rat. We set out to replicate and extend these effects...
Bell, David Robert, Clode, Sally, Fan, MingQi, Fernandes, Alwyn, Foster, Paul M D, Jiang, Tao, ...
We have investigated whether fetal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) causes defects in the male reproductive system of the rat, using chronically exposed rats to ensure...
Bell, David Robert, Clode, Sally, Fan, MingQi, Fernandes, Alwyn, Foster, Paul M D, Jiang, Tao, ...
We have investigated whether fetal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) causes defects in the male reproductive system of the rat, using chronically exposed rats to ensure...
Foster, Paul M. D., Harris, Martha W.
Previous studies have indicated that the androgen receptor antagonist, flutamide, can produce a suite of reproductive malformations in the male rat when orally administered daily on gestation days...
Bowman, Christopher J., Turner, Katie J., Sar, Madhabananda, Barlow, Norman J., Gaido, Kevin W., Foster, Paul M. D.
Di(n-butyl) phthalate (DBP) is a common plasticizer and solvent that disrupts androgen-dependent male reproductive development in rats. In utero exposure to 500 mg/kg/day DBP on gestation days (GD)...
Foster, Paul M. D., Harris, Martha W.
Previous studies have indicated that the androgen receptor antagonist, flutamide, can produce a suite of reproductive malformations in the male rat when orally administered daily on gestation days...
Bowman, Christopher J., Turner, Katie J., Sar, Madhabananda, Barlow, Norman J., Gaido, Kevin W., Foster, Paul M. D.
Di(n-butyl) phthalate (DBP) is a common plasticizer and solvent that disrupts androgendependent male reproductive development in rats. In utero exposure to 500 mg/kg/day DBP on gestation days (GD) 12...
Bowman, Christopher J., Turner, Katie J., Sar, Madhabananda, Barlow, Norman J., Gaido, Kevin W., Foster, Paul M. D.
Di(n-butyl) phthalate (DBP) is a common plasticizer and solvent that disrupts androgendependent male reproductive development in rats. In utero exposure to 500 mg/kg/day DBP on gestation days (GD) 12...
Lehmann, Kim P., Phillips, Suzanne, Sar, Madhabananda, Foster, Paul M. D., Gaido, Kevin W.
Exposure to di (n-butyl) phthalate (DBP) in utero impairs the development of the male rat reproductive tract. The adverse effects are due in part to a coordinated decrease in expression of genes...
Lehmann, Kim P., Phillips, Suzanne, Sar, Madhabananda, Foster, Paul M. D., Gaido, Kevin W.
Exposure to di (n-butyl) phthalate (DBP) in utero impairs development of the male rat reproductive tract. The adverse effects are due in part to a coordinated decrease in expression of genes involved...
Barlow, Norman J., Phillips, Suzanne L., Wallace, Duncan G., Sar, Madhabananda, Gaido, Kevin W., Foster, Paul M.D.
Di(n-butyl) phthalate (DBP) alters male reproductive development by decreasing testicular testosterone (T) production when fetuses are exposed on gestation days (GD) 12 to 21. Previous studies have...
Turner, Katie J., McIntyre, Barry S., Phillips, Suzanne L., Barlow, Norman J., Bowman, Christopher J., Foster, Paul M. D.
Linuron is a herbicide with weak androgen receptor (AR) antagonist activity. Exposure to linuron from gestation day (GD) 12 to 21 perturbs androgen-dependent male reproductive development. In utero...
Bowman, Christopher J., Barlow, Norman J., Turner, Katie J., Wallace, Duncan G., Foster, Paul M. D.
Finasteride is a specific inhibitor of type II 5α-reductase, the enzyme that converts testosterone (T) to the more potent androgen receptor agonist dihydrotestosterone (DHT). In utero exposure to...
Turner, Katie J., McIntyre, Barry S., Phillips, Suzanne L., Barlow, Norman J., Bowman, Christopher J., Foster, Paul M. D.
Linuron is an herbicide with weak androgen receptor (AR) antagonist activity. Exposure to linuron from gestation days (GD) 12 to 21 perturbs androgen-dependent male reproductive development. In utero...
Bowman, Christopher J., Barlow, Norman J., Turner, Katie J., Wallace, Duncan G., Foster, Paul M. D.
Finasteride is a specific inhibitor of type II 5α-reductase, the enzyme that converts testosterone (T) to the more potent androgen receptor agonist dihydrotestosterone (DHT). In utero exposure to...
Barlow, Norman J., Phillips, Suzanne L., Wallace, Duncan G., Sar, Madhabananda, Gaido, Kevin W., Foster, Paul M. D.
Di(n-butyl) phthalate (DBP) alters male reproductive development by decreasing testicular testosterone (T) production when fetuses are exposed on gestation days (GD) 12–21. Previous studies have...
Barlow, Norman J., Phillips, Suzanne L., Wallace, Duncan G., Sar, Madhabananda, Gaido, Kevin W., Foster, Paul M.D.
Di(n-butyl) phthalate (DBP) alters male reproductive development by decreasing testicular testosterone (T) production when fetuses are exposed on gestation days (GD) 12 to 21. Previous studies have...
Turner, Katie J., McIntyre, Barry S., Phillips, Suzanne L., Barlow, Norman J., Bowman, Christopher J., Foster, Paul M. D.
Linuron is a herbicide with weak androgen receptor (AR) antagonist activity. Exposure to linuron from gestation day (GD) 12 to 21 perturbs androgen-dependent male reproductive development. In utero...
Bowman, Christopher J., Barlow, Norman J., Turner, Katie J., Wallace, Duncan G., Foster, Paul M. D.
Finasteride is a specific inhibitor of type II 5α-reductase, the enzyme that converts testosterone (T) to the more potent androgen receptor agonist dihydrotestosterone (DHT). In utero exposure to...
McIntyre, Barry S., Barlow, Norman J., Foster, Paul M. D.
Prenatal exposure to the herbicide linuron, a weak androgen receptor antagonist, has been shown to perturb androgen-dependent male rat reproductive development as evidenced by slight decreases in...
Turner, Katie J., Barlow, Norman J., Struve, Melanie F., Wallace, Duncan G., Gaido, Kevin W., Dorman, David C., ...
Fenitrothion [0,0-dimethyl-O-(4-nitro-m-tolyl) phosphorothioate] is an organophosphate insecticide that has been shown to have antiandrogenic activity using in vitro and in vivo screening assays....
McIntyre, Barry S., Barlow, Norman J., Foster, Paul M. D.
Male offspring exposed in utero to antiandrogens often display alterations in androgen-dependent developmental markers (e.g., anogenital distance [AGD], nipple retention) together with clearly...
Altered Gene Profiles in Fetal Rat Testes after in Utero Exposure to Di(n-butyl) Phthalate (2001)
Shultz, Valerie D., Phillips, Suzanne, Sar, Madhabananda, Foster, Paul M. D., Gaido, Kevin W.
Di(n-butyl) phthalate (DBP) has antiandrogenic-like effects on the developing reproductive tract in the male rat and produces regions of interstitial cell hyperplasia and gonocyte degeneration in the...
Mylchreest, Eve, Wallace, Duncan G., Cattley, Russell C., Foster, Paul M. D.
Di(n-butyl) phthalate (DBP) is a commercially important plasticizer and ubiquitous environmental contaminant. Since previous, limited dose-response studies with DBP that reported alterations in male...
Mylchreest, Eve, Cattley, Russell C., Foster, Paul M. D.
Di(n-butyl) phthalate (DBP), a widely used plasticizer suspected of having estrogenic properties, was investigated for its effects on the prenatal and early neonatal development of the reproductive...
MCLAREN, TANYA T., FOSTER, PAUL M. D., SHARPE, RICHARD M.
The objective of this study was to identify effects of two known Sertoli cell toxicants on the secretion of proteins by seminiferous tubules (ST) isolated from adult rats at different stages of the...
ALLENBY, GARY, FOSTER, PAUL M. D., SHARPE, RICHARD M.
Evaluation of Changes in the Secretion of Immunoactive Inhibin by Adult Rat Seminiferous Tubules in Vitro as an Indicator of Early Toxicant Action on Spermatogenesis. Allenby, G., Foster, P. M. D.,...
Changes in Sertoli Cell Function in vitro Induced by Nitrobenzene (1990)
ALLENBY, GARY, SHARPE, RICHARD M., FOSTER, PAUL M. D.
Changes in Sertoli Cell Function in vitro Induced by Nitrobenzene. ALLENBY, G., SHARPE, R. M., AND FOSTER, P. M. D. (1990). Fundam. Appl. Toxicol 14, 364–375. Nitrobenzene (NB) has been identified...