Paul M. Grasby

Dopamine release in the human striatum: motor and cognitive tasks revisited. (2009)

Lappin, Julia M, Reeves, Suzanne J, Mehta, Mitul A, Egerton, Alice, Coulson, Mark, Grasby, Paul M

Striatal dopamine (DA) release has been shown during behavioural tasks, but the relative contribution of motor, reward, and cognitive components is unclear. Dopamine release was quantified using...

Dopamine release during sequential ®nger movements in health and Parkinson's disease: a PET study (2008)

Ines K. Goerendt, Cristina Messa, Andrew D. Lawrence, Paul M. Grasby, Paola Piccini, David J. Brooks, ...

Parkinson's disease is associated with slowness, especially of sequential movements, and is characterized pathologically by degeneration of dopaminergic neurons, particularly targeting...

Tyrosine depletion alters cortical and limbic blood flow but does not modulate spatial working memory performance or task-related blood flow in humans (2007)

Ellis, Kathryn A., Mehta, Mitul A., McTavish, Sarah F. B., Nathan, Pradeep J., Grasby, Paul M., ...

Dopamine appears critical in regulating spatial working memory (SWM) within the PFC of non-human primates; however findings in humans are less clear. Recent studies of the effects of global depletion...

Tyrosine depletion alters cortical and limbic blood flow but does not modulate spatial working memory performance or task-related blood flow in humans (2007)

Ellis, Kathryn A., Mehta, Mitul A., McTavish, Sarah F. B., Nathan, Pradeep J., Grasby, Paul M.

Dopamine appears critical in regulating spatial working memory (SWM) within the PFC of non-human primates; however findings in humans are less clear. Recent studies of the effects of global depletion...

Tyrosine depletion alters cortical and limbic blood flow but does not modulate spatial working memory performance or task-related blood flow in humans (2007)

Ellis, Kathryn A., Mehta, Mitul A., McTavish, Sarah F. B., Nathan, Pradeep J., Grasby, Paul M.

Dopamine appears critical in regulating spatial working memory (SWM) within the PFC of non-human primates; however findings in humans are less clear. Recent studies of the effects of global depletion...

Tyrosine depletion alters cortical and limbic blood flow but does not modulate spatial working memory performance or task-related blood flow in humans (2007)

Ellis, Kathryn A., Mehta, Mitul A., McTavish, Sarah F. B., Nathan, Pradeep J., Grasby, Paul M.

Dopamine appears critical in regulating spatial working memory (SWM) within the PFC of non-human primates; however findings in humans are less clear. Recent studies of the effects of global depletion...

Tyrosine depletion alters cortical and limbic blood flow but does not modulate spatial working memory performance or task-related blood flow in humans (2007)

Ellis, Kathryn A., Mehta, Mitul A., McTavish, Sarah F. B., Nathan, Pradeep J., Grasby, Paul M.

Dopamine appears critical in regulating spatial working memory (SWM) within the PFC of non-human primates; however findings in humans are less clear. Recent studies of the effects of global depletion...

Correction of Head Movement on PET Studies: Comparison of Methods (2006)

Andrew J. Montgomery, Kris Thielemans, Mitul A. Mehta, Federico Turkheimer, Sanida Mustafovic, Paul M. Grasby

Head movement presents a continuing problem in PET studies. Head restraint minimizes movement but is unreliable, resulting in the need to develop alternative strategies. These include frame-by-frame...

Dopamine release during sequential finger movements in health and Parkinson's disease: a PET study (2003)

Goerendt, Ines K., Messa, Cristina, Lawrence, Andrew D., Grasby, Paul M., Piccini, Paola, Brooks, David J.

Parkinson’s disease is associated with slowness, especially of sequential movements, and is characterized pathologically by degeneration of dopaminergic neurons, particularly targeting...