Pappano, William N, Jung, Paul M, Meulbroek, Jonathan A, Wang, Yi-Chun, Hubbard, Robert D, Zhang, Qian, ...
Abstract Background The insulin-like growth factor (IGF) axis is an important signaling pathway in the growth and survival of many cell and tissue types. This pathway has also been implicated in many...
Delivery of RNAi reagents in murine models of obesity and diabetes
Wilcox, Denise M, Yang, Ruojing, Morgan, Sherry J, Nguyen, Phong T, Voorbach, Martin J, Jung, Paul M, ...
RNA interference (RNAi) is an exciting new tool to effect acute in vivo knockdown of genes for pharmacological target validation. Testing the application of this technology to metabolic disease...