Genetic approaches to studying virulence and pathogenesis in Toxoplasma gondii.
Sibley, L David, Mordue, Dana G, Su, Chunlei, Robben, Paul M, Howe, Dan K
Toxoplasma gondii is a common protozoan parasite that causes disease in immunocompromised humans. Equipped with a wide array of experimental tools, T. gondii has rapidly developed as a model parasite...
Recruitment of Gr-1+ monocytes is essential for control of acute toxoplasmosis
Robben, Paul M., LaRegina, Marie, Kuziel, William A., Sibley, L. David
Circulating murine monocytes comprise two largely exclusive subpopulations that are responsible for seeding normal tissues (Gr-1−/CCR2−/CX3CR1high) or responding to sites of inflammation...