Seungchan Kima, Edward R. Doughertya, Michael L. Bittner, Yidong Chen, Krishnamoorthy Sivakumarc, Paul Meltzer, ...
A cDNA microarray is a complex biochemical-optical system whose purpose is the simultaneous measurement of gene expression for thousands of genes. This paper describes a general statistical...
National Institutes for Health (2007)
Seungchan Kim, Edward R. Dougherty, Michael L. Bittner, Yidong Chen, Krishnamoorthy Sivakumar, Paul Meltzer, ...
nonlinear framework for the analysis of gene
Kamradt, Jörn, Jung, Volker, Wahrheit, Kerstin, Tolosi, Laura, Rahnenführer, Jörg, Schilling, Martin, ...
Microarray expression profiling in melanoma reveals a BRAF mutation signature (2004)
Pavey, Sandra, Johansson, Peter, Packer, Leisl, Taylor, Jennifer, Stark, Mitchell, Pollock, Pamela M., ...
We have used microarray gene expression pro. ling and machine learning to predict the presence of BRAF mutations in a panel of 61 melanoma cell lines. The BRAF gene was found to be mutated in 42...
Soft tissue sarcomas of adults: state of the translational science (2003)
Baker, Laurence H, Bell, Robert S, Bramwell, Vivien, Demetri, George D, Eisenberg, Burton L, ...
Sarcomas--like leukemias, which are also mesodermal malignancies--carry biological significance disproportionate to their clinical frequency. Identification of mutations and translocations associated...
Ying, Hao, Suzuki, Hideyo, Furumoto, Hiroko, Walker, Robert, Meltzer, Paul, Willingham, Mark C., ...
The molecular genetics underlying thyroid carcinogenesis is not well understood. We have recently created a mutant mouse by targeting a mutation (PV) into the thyroid hormone receptor β gene (TRβPV...
Ying, Hao, Suzuki, Hideyo, Furumoto, Hiroko, Walker, Robert, Meltzer, Paul, Willingham, Mark C., ...
The molecular genetics underlying thyroid carcinogenesis is not well understood. We have recently created a mutant mouse by targeting a mutation (PV) into the thyroid hormone receptor β gene (TRβPV...
Ying, Hao, Suzuki, Hideyo, Furumoto, Hiroko, Walker, Robert, Meltzer, Paul, Willingham, Mark C., ...
The molecular genetics underlying thyroid carcinogenesis is not well understood. We have recently created a mutant mouse by targeting a mutation (PV) into the thyroid hormone receptor β gene (TRβPV...
Induction of Gene Expression as a Monitor of Exposure to Ionizing Radiation (2001)
Sally A. Amundson, Michael Bittner, Paul Meltzer, Jeffrey Trent, Albert J. Fornace Jr.
Amundson, S. A., Bittner, M., Meltzer, P., Trent, J. and Fornace, A. J., Jr. Induction of Gene Expression as a Monitor of Exposure to Ionizing Radiation. Radiat. Res. 156, 657–661 (2001). The...
Sally A. Amundson, Khanh T. Do, Sohrab Shahab, Michael Bittner, Paul Meltzer, Jeffrey Trent, ...
Amundson, S. A., Do, K. T., Shahab, S., Bittner, M., Meltzer, P., Trent, J. and Fornace, A. J., Jr. Identification of Potential mRNA Biomarkers in Peripheral Blood Lymphocytes for Human Exposure to...
Multivariate measurement of gene expression relationships (2000)
Seungchan Kim, Edward R. Dougherty, Yidong Chen, Krishnamoorthy Sivakumar, Paul Meltzer, Jeffery M. Trent, ...
The operational activities of cells are based on an awareness of their current state, coupled to a programmed response to internal and external cues in a context-dependent manner. One key goal of...
Wiegant, Joop, Bezrookove, Vladimir, Rosenberg, Carla, Tanke, Hans J., Raap, Anton K., Zhang, Hongen, ...
Suppressor role of activating transcription factor 2 (ATF2) in skin cancer
Bhoumik, Anindita, Fichtman, Boris, DeRossi, Charles, Breitwieser, Wolfgang, Kluger, Harriet M., Davis, Sean, ...
Activating transcription factor 2 (ATF2) regulates transcription in response to stress and growth factor stimuli. Here, we use a mouse model in which ATF2 was selectively deleted in keratinocytes....
A Molecular Function Map of Ewing's Sarcoma
Kauer, Maximilian, Ban, Jozef, Kofler, Reinhard, Walker, Bob, Davis, Sean, Meltzer, Paul, ...
Abnormalities of the large ribosomal subunit protein, Rpl35a, in Diamond-Blackfan anemia
Farrar, Jason E., Nater, Michelle, Caywood, Emi, McDevitt, Michael A., Kowalski, Jeanne, Takemoto, Clifford M., ...
Diamond-Blackfan anemia (DBA) is an inherited bone marrow failure syndrome characterized by anemia, congenital abnormalities, and cancer predisposition. Small ribosomal subunit genes RPS19, RPS24,...