Paul N. Durrington

Alstrom syndrome (OMIM 203800): a case report and literature review (2007)

Joy, Tisha, Cao, Henian, Black, Graeme, Malik, Rayaz, Charlton-Menys, Valentine, Hegele, Robert A, ...

Abstract Background Alstrom syndrome (AS) is a rare autosomal recessive disease characterized by multiorgan dysfunction. The key features are childhood obesity, blindness due to congenital retinal...

Adiponectin in umbillcal cord blood is inversely related to low-density lipoprotein cholesteril but not ethnicity (2006)

Bansal, Narinder, Charlton-Menys, Valentine, Pemberton, Philip, McElduff, Patrick, Oldroyd, John Charles, Vyas, Avni, ...

Context: Adiponectin is a recognized protective risk marker for cardiovascular disease in adults and is associated with an optimal lipid profile. The role of adiponectin at birth is not well...

Adiponectin in umbillcal cord blood is inversely related to low-density lipoprotein cholesteril but not ethnicity (2006)

Bansal, Narinder, Charlton-Menys, Valentine, Pemberton, Philip, McElduff, Patrick, Oldroyd, John Charles, Vyas, Avni, ...

Context: Adiponectin is a recognized protective risk marker for cardiovascular disease in adults and is associated with an optimal lipid profile. The role of adiponectin at birth is not well...

The Prevalence of Hyperlipidaemia and Related Clinical Features in Insulin-dependent Diabetes Mellitus (1989)

WINOCOUR, PETER H., DURRINGTON, PAUL N., ISHOLA, MONICA, HILLIER, VALERIE F., ANDERSON, DAVID C.

SUMMARY The Prevalence of hyperlipidaemia and related clinical features was examined in 205 individuals with insulin -dependent diabetes mellitus. Overall, 40 per cent (82) of the individuals had...

Effects of Insulin and Glucose on Very Low Density Lipoprotein Triglyceride Secretion by Cultured Rat Hepatocytes

Durrington, Paul N., Newton, Roger S., Weinstein, David B., Steinberg, Daniel

The effect of insulin on hepatic triglyceride synthesis and secretion is controversial. Previously, we have described a cell culture system of adult rat hepatocytes that synthesize and secrete very...

Risks and benefits of omega 3 fats for mortality, cardiovascular disease, and cancer: systematic review

Hooper, Lee, Thompson, Rachel L, Harrison, Roger A, Summerbell, Carolyn D, Ness, Andy R, Moore, Helen J, ...

Objective To review systematically the evidence for an effect of long chain and shorter chain omega 3 fatty acids on total mortality, cardiovascular events, and cancer.

Effects of Insulin and Glucose on Very Low Density Lipoprotein Triglyceride Secretion by Cultured Rat Hepatocytes

Durrington, Paul N., Newton, Roger S., Weinstein, David B., Steinberg, Daniel

The effect of insulin on hepatic triglyceride synthesis and secretion is controversial. Previously, we have described a cell culture system of adult rat hepatocytes that synthesize and secrete very...

Risks and benefits of omega 3 fats for mortality, cardiovascular disease, and cancer: systematic review

Hooper, Lee, Thompson, Rachel L, Harrison, Roger A, Summerbell, Carolyn D, Ness, Andy R, Moore, Helen J, ...

Objective To review systematically the evidence for an effect of long chain and shorter chain omega 3 fatty acids on total mortality, cardiovascular events, and cancer.

Sequencing of the Reannotated LMNB2 Gene Reveals Novel Mutations in Patients with Acquired Partial Lipodystrophy

Hegele, Robert A., Cao, Henian, Liu, Dora M., Costain, Gary A., Charlton-Menys, Valentine, Rodger, N. Wilson, ...

The etiology of acquired partial lipodystrophy (APL, also called “Barraquer-Simons syndrome”) is unknown. Genomic DNA mutations affecting the nuclear lamina protein lamin A cause inherited...

Effect of the molecular polymorphisms of human paraoxonase (PON1) on the rate of hydrolysis of paraoxon

Mackness, Bharti, Mackness, Michael I, Arrol, Sharon, Turkie, Wajdi, Durrington, Paul N

The hydrolysis of organophosphate pesticides (OP) and nerve gases by serum paraoxonase (PON1) is an important factor determining their toxicity to mammals including man. The PON1 gene contains 2...