Modular alpha-helical mimetics with antiviral activity against respiratory syncitial virus (2006)
Shepherd, Nicholas E., Hoang, Huy N., Desai, Vishal S., Letouze, Eric, Young, Paul R., Fairlie, David P.
A 13-residue peptide sequence from a respiratory syncitial virus fusion protein was constrained in an alpha-helical conformation by fusing two back-to-back cyclic alpha-turn mimetics. The resulting...
The role of histidine residues in low-pH-mediated viral membrane fusion (2006)
Kampmann,Thorsten, Meuller, Daniela S., Mark, Alan E., Young, Paul R., Kobe, Bostjan
A central event in the invasion of a host cell by an enveloped virus is the fusion of viral and cell membranes. For many viruses, membrane fusion is driven by specific viral surface proteins that...
Keith J. Chappell, Tessa A. Nall, Martin J. Stoermer, Ning-Xia Fang, David P. Fairlie, ...
A series of papers that have been published since our 2001 paper (above) has built on our understanding of flavivirus protease specificity. We have expanded our studies to incorporate West Nile virus...
Keith J. Chappell, Tessa A. Nall, Martin J. Stoermer, Ning-Xia Fang, David P. Fairlie, ...
A series of papers that have been published since our 2001 paper (above) has built on our understanding of flavivirus protease specificity. We have expanded our studies to incorporate West Nile virus...
Chappell, Keith J., Nall, Tessa A., Stoermer, Martin J., Fang, Ning-Xia, Tyndall, Joel D. A., Fairlie, David P., ...
The flavivirus West Nile virus (WNV) has spread rapidly throughout the world in recent years causing fever, meningitis, encephalitis, and fatalities. Because the viral protease NS2B/NS3 is essential...
Daniel H. Libraty, Paul R. Young, Darren Pickering, Timothy P. Endy, Siripen Kalayanarooj, Sharone Green, ...
This paper builds clinical experience onto our earlier development and publication (Young et al, Journal of Clinical Microbiology, 2000) of an antigen capture assay for dengue diagnosis. The assay...
Properties of Selected S-Nitrosothiols Compared to Nitrosylated WR-1065 (2002)
William Michael Whiteside, Devin N. Sears, Paul R. Young, David B. Rubin
Whiteside, W. M., Sears, D. N., Young, P. R. and Rubin, D. B. Properties of Selected S-Nitrosothiols Compared to Nitrosylated WR-1065. Radiat. Res. 157, 578–588 (2002). WR-1065...
Daniel H. Libraty, Paul R. Young, Darren Pickering, Timothy P. Endy, Siripen Kalayanarooj, Sharone Green, ...
This paper builds clinical experience onto our earlier development and publication (Young et al, Journal of Clinical Microbiology, 2000) of an antigen capture assay for dengue diagnosis. The assay...
Donmienne Leung, Kate Schroder, Helen White, Ning-Xia Fang, Martin J. Stoermer, Giovanni Abbenante, ...
Our paper describes the expression and purification of the first active recombinant flavivirus protease suitable for in vitro assays. We used this assay to probe substrate specificity and develop the...
Basic Mass Spectroscopy (2001)
This site presents material on fragmentation and the interpretation of mass spectra. This site also contains problems consisting of the mass spectra of 5 unknowns along with solutions for the...
Leung, Donmienne, Schroder, Kate, White, Helen, Fang, Ning-Xia, Stoermer, Martin J., Abbenante, Giovanni, ...
Thesis--University of South Florida.
An analysis of the enrollment in junior extension work in New York State, 1920-1924. (1925)
Thesis (M.S.)--Cornell Univ., June 1925.
Young, Paul R., Hilditch, Paige A., Bletchly, Cheryl, Halloran, Wendy
We describe the development of a capture enzyme-linked immunosorbent assay for the detection of the dengue virus nonstructural protein NS1. The assay employs rabbit polyclonal and monoclonal...
Varnavski, Andrei N., Young, Paul R., Khromykh, Alexander A.
Primary features of the flavivirus Kunjin (KUN) subgenomic replicons include continuous noncytopathic replication in host cell cytoplasm and the ability to be encapsidated into secreted virus-like...
Young, Paul R., Hilditch, Paige A., Bletchly, Cheryl, Halloran, Wendy
We describe the development of a capture enzyme-linked immunosorbent assay for the detection of the dengue virus nonstructural protein NS1. The assay employs rabbit polyclonal and monoclonal...
Varnavski, Andrei N., Young, Paul R., Khromykh, Alexander A.
Primary features of the flavivirus Kunjin (KUN) subgenomic replicons include continuous noncytopathic replication in host cell cytoplasm and the ability to be encapsidated into secreted virus-like...
This is a straight forward elementary approach to proton and carbon NMR analysis targeted at students who are just at the most beginning stages of NMR spectroscopy, for example those in a...
Donmienne Leung, Kate Schroder, Helen White, Ning-Xia Fang, Martin J. Stoermer, Giovanni Abbenante, ...
Our paper describes the expression and purification of the first active recombinant flavivirus protease suitable for in vitro assays. We used this assay to probe substrate specificity and develop the...