Paul W. Sanders

Association of chronic kidney disease with outcomes in chronic heart failure: a propensity-matched study (2009)

Campbell, Ruth C., Sui, Xuemei, Filippatos, Gerasimos, Love, Thomas E., Wahle, Christy, Sanders, Paul W., ...

Background. Chronic kidney disease (CKD) is associated with increased mortality in patients with heart failure (HF). However, its association with hospitalization in HF patients has not been well...

AL-amyloidosis is underdiagnosed in renal biopsies (2004)

Novak, Lea, Cook, William J., Herrera, Guillermo A., Sanders, Paul W.

Background. Renal amyloidosis is associated with a variety of underlying disease processes. Although amyloid is identical in appearance in these diseases, the precursor proteins are different....

AL-amyloidosis is underdiagnosed in renal biopsies (2004)

Novak, Lea, Cook, William J., Herrera, Guillermo A., Sanders, Paul W.

Background. Renal amyloidosis is associated with a variety of underlying disease processes. Although amyloid is identical in appearance in these diseases, the precursor proteins are different....

Activation of the Fas/Fas ligand pathway in hypertensive renal disease in Dahl/Rapp rats (2002)

Sanders, Paul W, Wang, Pei-Xuan

Abstract Background Hypertensive nephrosclerosis is the second most common cause of end-stage renal failure in the United States. The mechanism by which hypertension produces renal failure is...

Accelerated ubiquitination and proteasome degradation of a genetic variant of inducible nitric oxide synthase.

Ying, Wei-Zhong, Sanders, Paul W

Biochemical and pharmacological studies have suggested that NOS2 (inducible nitric oxide synthase) has a functional role in the blood pressure response to increases in dietary salt intake. On a...

Accelerated ubiquitination and proteasome degradation of a genetic variant of inducible nitric oxide synthase.

Ying, Wei-Zhong, Sanders, Paul W

Biochemical and pharmacological studies have suggested that NOS2 (inducible nitric oxide synthase) has a functional role in the blood pressure response to increases in dietary salt intake. On a...

The Distribution and Regulation of Integrin-Linked Kinase in Normal and Diabetic Kidneys

Guo, Lida, Sanders, Paul W., Woods, Anne, Wu, Chuanyue

Alteration in cell adhesion and extracellular matrix deposition is a hallmark of diabetic glomerulosclerosis. Integrin-linked kinase (ILK) is a recently identified integrin cytoplasmic-binding...

Mapping the Binding Domain of Immunoglobulin Light Chains for Tamm-Horsfall Protein

Ying, Wei-Zhong, Sanders, Paul W.

Cast nephropathy, or myeloma kidney, is a potentially reversible cause of chronic renal failure. In this condition, filtered light chains bind to a common site on Tamm-Horsfall protein (THP), which...

Contribution of intrarenal cells to cellular repair after acute kidney injury: subcapsular implantation technique

Curtis, Lisa M., Chen, Sifeng, Chen, Bo, Agarwal, Anupam, Klug, Christopher A., Sanders, Paul W.

The kidney is capable of regeneration following injury, particularly following acute insults. Although the mechanisms underlying cellular regeneration are incompletely understood, emerging evidence...

Mechanism of dietary salt-mediated increase in intravascular production of TGF-β1

Ying, Wei-Zhong, Aaron, Kristal, Sanders, Paul W.

Clinical and preclinical studies have demonstrated an important effect of arterial pathobiology on the progressive loss of renal function that occurs in chronic kidney disease. Chronic kidney...