Paul Wordsworth

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants (2007)

Newport, Melanie, Sirugo, Giorgio, Lyons, Emily, Vannberg, Fredrik, Hill, Adrian V. S., Bradbury, Linda A., ...

We have genotyped 14,436 nonsynonymous SNPs (nsSNPs) and 897 major histocompatibility complex (MHC) tag SNPs from 1,000 independent cases of ankylosing spondylitis ( AS), autoimmune thyroid disease...

Suggestive evidence for association of human chromosome 18q12-q21 and its orthologue on rat and mouse chromosome 18 with several autoimmune diseases (2001)

Merriman, Terry R., Cordell, Heather J., Eaves, Iain A., Danoy, Patrick A., Coraddu, Francesca, Barber, Rachael, ...

Some immune system disorders, such as type 1 diabetes, multiple sclerosis (MS), and rheumatoid arthritis (RA), share common features: the presence of autoantibodies and self-reactive T-cells, and a...

Suggestive evidence for association of human chromosome 18q12-q21 and its orthologue on rat and mouse chromosome 18 with several autoimmune diseases (2001)

Merriman, Terry R., Cordell, Heather J., Eaves, Iain A., Danoy, Patrick A., Coraddu, Francesca, Barber, Rachael, ...

Some immune system disorders, such as type 1 diabetes, multiple sclerosis (MS), and rheumatoid arthritis (RA), share common features: the presence of autoantibodies and self-reactive T-cells, and a...

Suggestive evidence for association of human chromosome 18q12-q21 and its orthologue on rat and mouse chromosome 18 with several autoimmune diseases (2001)

Merriman, Terry R., Cordell, Heather J., Eaves, Iain A., Danoy, Patrick A., Coraddu, Francesca, Barber, Rachael, ...

Some immune system disorders, such as type 1 diabetes, multiple sclerosis (MS), and rheumatoid arthritis (RA), share common features: the presence of autoantibodies and self-reactive T-cells, and a...

Bone and joint disease in human beings and animals

Pile, Kevin, Wordsworth, Paul

Consistent linkage of dominantly inherited osteogenesis imperfecta to the type I collagen loci: COL1A1 and COL1A2

Sykes, Bryan, Ogilvie, Donald, Wordsworth, Paul, Wallis, Gillian, Mathew, Chris, Beighton, Peter, ...

The segregation of COL1A1 and COL1A2, the two genes which encode the chains of type I collagen, was analyzed in 38 dominant osteogenesis imperfecta (OI) pedigrees by using polymorphic markers within...

Bone and joint disease in human beings and animals

Pile, Kevin, Wordsworth, Paul

Consistent linkage of dominantly inherited osteogenesis imperfecta to the type I collagen loci: COL1A1 and COL1A2

Sykes, Bryan, Ogilvie, Donald, Wordsworth, Paul, Wallis, Gillian, Mathew, Chris, Beighton, Peter, ...

The segregation of COL1A1 and COL1A2, the two genes which encode the chains of type I collagen, was analyzed in 38 dominant osteogenesis imperfecta (OI) pedigrees by using polymorphic markers within...

Genetic Mapping of a Locus for Multiple Epiphyseal Dysplasia (EDM2) to a Region of Chromosome 1 Containing a Type IX Collagen Gene

Briggs, Michael D., Choi, HiChang, Warman, Matthew L., Loughlin, John A., Wordsworth, Paul, Sykes, Bryan C., ...

Multiple epiphyseal dysplasia (MED) is a dominantly inherited chondrodysplasia characterized by mild short stature and early-onset osteoarthrosis. Some forms of MED clinically resemble another...

Re-evaluation of putative rheumatoid arthritis susceptibility genes in the post-genome wide association study era and hypothesis of a key pathway underlying susceptibility

Barton, Anne, Thomson, Wendy, Ke, Xiayi, Eyre, Steve, Hinks, Anne, Bowes, John, ...

Rheumatoid arthritis (RA) is an archetypal, common, complex autoimmune disease with both genetic and environmental contributions to disease aetiology. Two novel RA susceptibility loci have been...

Rehabilitation in Rheumatology: the Team Approach

Wordsworth, Paul