The role of angiogenesis inhibitors in cutaneous inflammation / (2005)
Kiel, Univ., Diss., 2005.
Bertoncini, Jennifer, Velasco, Paula, Brown, Lawrence F, Detmar, Michael
Angiogenesis is a prominent feature of a number of inflammatory human diseases, including rheumatoid arthritis, psoriasis, and cutaneous delayed-type hypersensitivity (DTH) reactions. Up-regulation...
Thrombospondin-2: A potent endogenous inhibitor of tumor growth and angiogenesis
Streit, Michael, Riccardi, Lucia, Velasco, Paula, Brown, Lawrence F., Hawighorst, Thomas, Bornstein, Paul, ...
Recent evidence suggests a potential role for thrombospondin-2 (TSP-2), a matricellular glycoprotein, in the regulation of primary angiogenesis. To directly examine the biological effect of TSP-2...
Hawighorst, Thomas, Velasco, Paula, Streit, Michael, Hong, Young-Kwon, Kyriakides, Themis R., Brown, Lawrence F., ...
The angiogenic switch during tumorigenesis is thought to be induced by a change in the balance of pro- angiogenic and anti-angiogenic factors. To elucidate the biological role of the endogenous...
Molecular characterization of lymphatic endothelial cells
Podgrabinska, Simona, Braun, Pascal, Velasco, Paula, Kloos, Bryan, Pepper, Michael S., Jackson, David G., ...
The lymphatic microvasculature is uniquely adapted for the continuous removal of interstitial fluid and proteins and is an important entry point for leukocytes and tumor cells. Specialized functions...
Streit, Michael, Velasco, Paula, Riccardi, Lucia, Spencer, Lisa, Brown, Lawrence F., Janes, Lauren, ...
The function of the endogenous angiogenesis inhibitor thrombospondin-1 (TSP-1) in tissue repair has remained controversial. We established transgenic mice with targeted overexpression of TSP-1 in the...
Thrombospondin-2: A potent endogenous inhibitor of tumor growth and angiogenesis
Streit, Michael, Riccardi, Lucia, Velasco, Paula, Brown, Lawrence F., Hawighorst, Thomas, Bornstein, Paul, ...
Recent evidence suggests a potential role for thrombospondin-2 (TSP-2), a matricellular glycoprotein, in the regulation of primary angiogenesis. To directly examine the biological effect of TSP-2...
Hawighorst, Thomas, Velasco, Paula, Streit, Michael, Hong, Young-Kwon, Kyriakides, Themis R., Brown, Lawrence F., ...
The angiogenic switch during tumorigenesis is thought to be induced by a change in the balance of pro- angiogenic and anti-angiogenic factors. To elucidate the biological role of the endogenous...
Molecular characterization of lymphatic endothelial cells
Podgrabinska, Simona, Braun, Pascal, Velasco, Paula, Kloos, Bryan, Pepper, Michael S., Jackson, David G., ...
The lymphatic microvasculature is uniquely adapted for the continuous removal of interstitial fluid and proteins and is an important entry point for leukocytes and tumor cells. Specialized functions...
Streit, Michael, Velasco, Paula, Riccardi, Lucia, Spencer, Lisa, Brown, Lawrence F., Janes, Lauren, ...
The function of the endogenous angiogenesis inhibitor thrombospondin-1 (TSP-1) in tissue repair has remained controversial. We established transgenic mice with targeted overexpression of TSP-1 in the...
Detmar, Michael, Velasco, Paula, Richard, Lisa, Claffey, Kevin P., Streit, Michael, Riccardi, Lucia, ...
Inhibition of the vascular endothelial growth factor (VEGF) receptor Flk-1 has been shown to prevent invasion of experimental squamous cell carcinomas (SCC). To directly investigate the role of VEGF...
Streit, Michael, Velasco, Paula, Brown, Lawrence F., Skobe, Mihaela, Richard, Lisa, Riccardi, Lucia, ...
The function of the endogenous angiogenesis inhibitor thrombospondin-1 (TSP-1) in epithelial tumor development has remained controversial. We studied the in vitro growth characteristics and the in...
Hawighorst, Thomas, Skobe, Mihaela, Streit, Michael, Hong, Young-Kwon, Velasco, Paula, Brown, Lawrence F., ...
The distinct roles of angiopoietin (Ang)-1 and Ang2, counteracting ligands for the endothelium-specific Tie2 receptor, in tumor development and progression have remained poorly understood. We...