Gruenheid, Samantha, Sekirov, Inna, Thomas, Nikhil A., Deng, Wanyin, O'Donnell, Paul, Goode, David, ...
Enterohaemorrhagic Escherichia coli (EHEC) O157:H7 uses a specialized protein translocation apparatus, the type III secretion system (TTSS), to deliver bacterial effector proteins into host cells....
Gruenheid, Samantha, Sekirov, Inna, Thomas, Nikhil A., Deng, Wanyin, O'Donnell, Paul, Goode, David, ...
Enterohaemorrhagic Escherichia coli (EHEC) O157:H7 uses a specialized protein translocation apparatus, the type III secretion system (TTSS), to deliver bacterial effector proteins into host cells....
Gruenheid, Samantha, Sekirov, Inna, Thomas, Nikhil A., Deng, Wanyin, O'Donnell, Paul, Goode, David, ...
Enterohaemorrhagic Escherichia coli (EHEC) O157:H7 uses a specialized protein translocation apparatus, the type III secretion system (TTSS), to deliver bacterial effector proteins into host cells....
Gruenheid, Samantha, Sekirov, Inna, Thomas, Nikhil A., Deng, Wanyin, O'Donnell, Paul, Goode, David, ...
Enterohaemorrhagic Escherichia coli (EHEC) O157:H7 uses a specialized protein translocation apparatus, the type III secretion system (TTSS), to deliver bacterial effector proteins into host cells....
Dissecting virulence: Systematic and functional analyses of a pathogenicity island
Deng, Wanyin, Puente, José L., Gruenheid, Samantha, Li, Yuling, Vallance, Bruce A., Vázquez, Alejandra, ...
Bacterial pathogenicity islands (PAI) often encode both effector molecules responsible for disease and secretion systems that deliver these effectors to host cells. Human enterohemorrhagic...
Xrcc4 physically links DNA end processing by polynucleotide kinase to DNA ligation by DNA ligase IV
Koch, Christine Anne, Agyei, Roger, Galicia, Sarah, Metalnikov, Pavel, O'Donnell, Paul, Starostine, Andrei, ...
Nonhomologous end joining (NHEJ) is the major DNA double-strand break (DSB) repair pathway in mammalian cells. A critical step in this process is DNA ligation, involving the Xrcc4–DNA ligase IV...
WW Domains Provide a Platform for the Assembly of Multiprotein Networks†
Ingham, Robert J., Colwill, Karen, Howard, Caley, Dettwiler, Sabine, Lim, Caesar S. H., Yu, Joanna, ...
WW domains are protein modules that mediate protein-protein interactions through recognition of proline-rich peptide motifs and phosphorylated serine/threonine-proline sites. To pursue the functional...
Dissecting virulence: Systematic and functional analyses of a pathogenicity island
Deng, Wanyin, Puente, José L., Gruenheid, Samantha, Li, Yuling, Vallance, Bruce A., Vázquez, Alejandra, ...
Bacterial pathogenicity islands (PAI) often encode both effector molecules responsible for disease and secretion systems that deliver these effectors to host cells. Human enterohemorrhagic...
Xrcc4 physically links DNA end processing by polynucleotide kinase to DNA ligation by DNA ligase IV
Koch, Christine Anne, Agyei, Roger, Galicia, Sarah, Metalnikov, Pavel, O'Donnell, Paul, Starostine, Andrei, ...
Nonhomologous end joining (NHEJ) is the major DNA double-strand break (DSB) repair pathway in mammalian cells. A critical step in this process is DNA ligation, involving the Xrcc4–DNA ligase IV...
WW Domains Provide a Platform for the Assembly of Multiprotein Networks†
Ingham, Robert J., Colwill, Karen, Howard, Caley, Dettwiler, Sabine, Lim, Caesar S. H., Yu, Joanna, ...
WW domains are protein modules that mediate protein-protein interactions through recognition of proline-rich peptide motifs and phosphorylated serine/threonine-proline sites. To pursue the functional...
Luke-Glaser, Sarah, Roy, Marcia, Larsen, Brett, Le Bihan, Thierry, Metalnikov, Pavel, Tyers, Mike, ...
The COP9/signalosome (CSN) is an evolutionarily conserved macromolecular complex that regulates the cullin-RING ligase (CRL) class of E3 ubiquitin ligases, primarily by removing the ubiquitin-like...
Protein phosphatase 1 regulates the phosphorylation state of the polarity scaffold Par-3
Traweger, Andreas, Wiggin, Giselle, Taylor, Lorne, Tate, Stephen A., Metalnikov, Pavel, Pawson, Tony
Phosphorylation of the polarity protein Par-3 by the serine/threonine kinases aPKCζ/ι and Par-1 (EMK1/MARK2) regulates various aspects of epithelial cell polarity, but little is known about the...