Palomero, Teresa, Lim, Wei Keat, Odom, Duncan T., Sulis, Maria Luisa, Real, Pedro J., Margolin, Adam, ...
The NOTCH1 signaling pathway directly links extracellular signals with transcriptional responses in the cell nucleus and plays a critical role during T cell development and in the pathogenesis over...
NOTCH1 extracellular juxtamembrane expansion mutations in T-ALL
Sulis, Maria Luisa, Williams, Odette, Palomero, Teresa, Tosello, Valeria, Pallikuppam, Sasikala, Real, Pedro J., ...
Heterodimerization domain (HD) mutations in NOTCH1 induce ligand-independent activation of the receptor and contribute to the pathogenesis of one-third of human T-cell lymphoblastic leukemias...