Cahan, Patrick, Godfrey, Laura E., Eis, Peggy S., Richmond, Todd A., Selzer, Rebecca R., Brent, Michael, ...
Copy number variants (CNVs) are currently defined as genomic sequences that are polymorphic in copy number and range in length from 1000 to several million base pairs. Among current array-based CNV...
Characterization of a recurrent 15q24 microdeletion syndrome (2007)
Sharp, Andrew J., Selzer, Rebecca R., Veltman, Joris A., Gimelli, Stefania, Gimelli, Giorgio, Striano, Pasquale, ...
We describe multiple individuals with mental retardation and overlapping de novo submicroscopic deletions of 15q24 (1.7–3.9 Mb in size). High-resolution analysis showed that in three patients both...
A High-Resolution Map of Segmental DNA Copy Number Variation in the Mouse Genome (2007)
Timothy A. Graubert, Patrick Cahan, Deepa Edwin, Rebecca R. Selzer, Todd A. Richmond, Peggy S. Eis, ...
Submicroscopic (less than 2 Mb) segmental DNA copy number changes are a recently recognized source of genetic variability between individuals. The biological consequences of copy number variants...
Characterization of a recurrent 15q24 microdeletion syndrome (2007)
Sharp, Andrew J, Selzer, Rebecca R, Veltman, Joris A, Gimelli, Stefania, Gimelli, Giorgio, Striano, Pasquale, ...
We describe multiple individuals with mental retardation and overlapping de novo submicroscopic deletions of 15q24 (1.7-3.9 Mb in size). High resolution analysis showed that in three patients both...
Ghosh, Soumitra S., Eis, Peggy S., Blumeyer, Kirsten, Fearon, Kim, Millar, David P.
The kinetics of PaeR7 endonuclease-catalysed cleavage reactions of fluorophor-labeled oligonucleotide substrates have been examined using fluorescence resonance energy transfer (FRET). A series of...
Sensitive detection of DNA polymorphisms by the serial invasive signal amplification reaction
Hall, Jeff G., Eis, Peggy S., Law, Scott M., Reynaldo, Luis P., Prudent, James R., Marshall, David J., ...
The invasive signal amplification reaction has been previously developed for quantitative detection of nucleic acids and discrimination of single-nucleotide polymorphisms. Here we describe a method...
Quantification of alternatively spliced FGFR2 RNAs using the RNA invasive cleavage assay
WAGNER, ERIC J., CURTIS, MICHELLE L., ROBSON, NICOLE D., BARANIAK, ANDREW P., EIS, PEGGY S., GARCIA-BLANCO, MARIANO A.
The regulated splicing of fibroblast growth factor receptor-2 (FGFR2) transcripts leads to tissue-specific expression of distinct receptor isoforms. These isoforms contain two different versions of...
Sensitive detection of DNA polymorphisms by the serial invasive signal amplification reaction
Hall, Jeff G., Eis, Peggy S., Law, Scott M., Reynaldo, Luis P., Prudent, James R., Marshall, David J., ...
The invasive signal amplification reaction has been previously developed for quantitative detection of nucleic acids and discrimination of single-nucleotide polymorphisms. Here we describe a method...
Accumulation of miR-155 and BIC RNA in human B cell lymphomas
Eis, Peggy S., Tam, Wayne, Sun, Liping, Chadburn, Amy, Li, Zongdong, Gomez, Mario F., ...
We show that the microRNA miR-155 can be processed from sequences present in BIC RNA, a spliced and polyadenylated but non-protein-coding RNA that accumulates in lymphoma cells. The precursor of...
Quantification of alternatively spliced FGFR2 RNAs using the RNA invasive cleavage assay
WAGNER, ERIC J., CURTIS, MICHELLE L., ROBSON, NICOLE D., BARANIAK, ANDREW P., EIS, PEGGY S., GARCIA-BLANCO, MARIANO A.
The regulated splicing of fibroblast growth factor receptor-2 (FGFR2) transcripts leads to tissue-specific expression of distinct receptor isoforms. These isoforms contain two different versions of...
A High-Resolution Map of Segmental DNA Copy Number Variation in the Mouse Genome
Graubert, Timothy A, Cahan, Patrick, Edwin, Deepa, Selzer, Rebecca R, Richmond, Todd A, Eis, Peggy S, ...
Submicroscopic (less than 2 Mb) segmental DNA copy number changes are a recently recognized source of genetic variability between individuals. The biological consequences of copy number variants...
Cahan, Patrick, Godfrey, Laura E., Eis, Peggy S., Richmond, Todd A., Selzer, Rebecca R., Brent, Michael, ...
Copy number variants (CNVs) are currently defined as genomic sequences that are polymorphic in copy number and range in length from 1000 to several million base pairs. Among current array-based CNV...
Acquired copy number alterations in adult acute myeloid leukemia genomes
Walter, Matthew J., Payton, Jacqueline E., Ries, Rhonda E., Shannon, William D., Deshmukh, Hrishikesh, Zhao, Yu, ...
Cytogenetic analysis of acute myeloid leukemia (AML) cells has accelerated the identification of genes important for AML pathogenesis. To complement cytogenetic studies and to identify genes altered...