Per G. Falk

Epithelial attachment alters the outcome of Helicobacter pylori infection

Guruge, Janaki L., Falk, Per G., Lorenz, Robin G., Dans, Maria, Wirth, Hans-Peter, Blaser, Martin J., ...

Genetically defined in vivo models are needed to assess the importance of target cell attachment in bacterial pathogenesis. Gastric colonization by Helicobacter pylori in human populations is common...

A molecular sensor that allows a gut commensal to control its nutrient foundation in a competitive ecosystem

Hooper, Lora V., Xu, Jian, Falk, Per G., Midtvedt, Tore, Gordon, Jeffrey I.

Little is known about how members of the indigenous microflora interact with their mammalian hosts to establish mutually beneficial relationships. We have used a gnotobiotic mouse model to show that...

Mutation frequency and biological cost of antibiotic resistance in Helicobacter pylori

Björkholm, Britta, Sjölund, Maria, Falk, Per G., Berg, Otto G., Engstrand, Lars, Andersson, Dan I.

Among the several factors that affect the appearance and spread of acquired antibiotic resistance, the mutation frequency and the biological cost of resistance are of special importance. Measurements...

Creating and Maintaining the Gastrointestinal Ecosystem: What We Know and Need To Know from Gnotobiology

Falk, Per G., Hooper, Lora V., Midtvedt, Tore, Gordon, Jeffrey I.

Studying the cross talk between nonpathogenic organisms and their mammalian hosts represents an experimental challenge because these interactions are typically subtle and the microbial societies that...

Epithelial attachment alters the outcome of Helicobacter pylori infection

Guruge, Janaki L., Falk, Per G., Lorenz, Robin G., Dans, Maria, Wirth, Hans-Peter, Blaser, Martin J., ...

Genetically defined in vivo models are needed to assess the importance of target cell attachment in bacterial pathogenesis. Gastric colonization by Helicobacter pylori in human populations is common...

A molecular sensor that allows a gut commensal to control its nutrient foundation in a competitive ecosystem

Hooper, Lora V., Xu, Jian, Falk, Per G., Midtvedt, Tore, Gordon, Jeffrey I.

Little is known about how members of the indigenous microflora interact with their mammalian hosts to establish mutually beneficial relationships. We have used a gnotobiotic mouse model to show that...

Mutation frequency and biological cost of antibiotic resistance in Helicobacter pylori

Björkholm, Britta, Sjölund, Maria, Falk, Per G., Berg, Otto G., Engstrand, Lars, Andersson, Dan I.

Among the several factors that affect the appearance and spread of acquired antibiotic resistance, the mutation frequency and the biological cost of resistance are of special importance. Measurements...

Creating and Maintaining the Gastrointestinal Ecosystem: What We Know and Need To Know from Gnotobiology

Falk, Per G., Hooper, Lora V., Midtvedt, Tore, Gordon, Jeffrey I.

Studying the cross talk between nonpathogenic organisms and their mammalian hosts represents an experimental challenge because these interactions are typically subtle and the microbial societies that...