Pete Kaiser

Salmonella Enteritidis–Induced Alteration of Inflammatory CXCL Chemokine Messenger-RNA Expression and Histologic Changes in the Ceca of Infected Chicks (2008)

Jennifer H. Cheeseman, Nyssa A. Levy, Pete Kaiser, Hyun S. Lillehoj, Susan J. Lamont

To understand better the events in early avian host immune responses to Salmonella Enteritidis (SE), we examined messenger-RNA (mRNA) expression for eight genes: CXCLi1[K60], CXCLi2 [IL-8/CAF],...

Salmonella enterica Serovar Enteritidis Induced Alteration of Inflammatory Cxcl Chemokine Mrna Expression and Histological Changes In the Ceca of Infected Chicks (2008)

Jennifer H. Cheeseman, Nyssa A. Levy, Pete Kaiser, Hyun S. Lillehoj, Susan J. Lamont

Differential Cytokine Responses following Marek's Disease Virus Infection of Chickens Differing in Resistance to Marek's Disease

Kaiser, Pete, Underwood, Greg, Davison, Fred

The production of cytokine mRNAs, in addition to viral DNA, was quantified by real-time quantitative reverse transcription-PCR (RT-PCR) (cytokines) or PCR (virus) in splenocytes during the course of...

In Vitro and In Ovo Expression of Chicken Gamma Interferon by a Defective RNA of Avian Coronavirus Infectious Bronchitis Virus

Hackney, Karen, Cavanagh, Dave, Kaiser, Pete, Britton, Paul

Coronavirus defective RNAs (D-RNAs) have been used for site-directed mutagenesis of coronavirus genomes and for expression of heterologous genes. D-RNA CD-61 derived from the avian coronavirus...

Toll-Like Receptor Expression in C3H/HeN and C3H/HeJ Mice during Salmonella enterica Serovar Typhimurium Infection

Tötemeyer, Sabine, Foster, Neil, Kaiser, Pete, Maskell, Duncan J., Bryant, Clare E.

Here, we have investigated the mRNA expression of Toll-like receptor 2 (TLR-2), TLR-4, and MD-2 in spleens and livers of C3H/HeN mice (carrying wild-type TLR-4) and C3H/HeJ mice (carrying mutated...

Rapid Expression of Chemokines and Proinflammatory Cytokines in Newly Hatched Chickens Infected with Salmonella enterica Serovar Typhimurium

Withanage, G. S. K., Kaiser, Pete, Wigley, Paul, Powers, Claire, Mastroeni, Pietro, Brooks, Heather, ...

Poultry meat and eggs contaminated with Salmonella enterica serovar Enteritidis or Salmonella enterica serovar Typhimurium are common sources of acute gastroenteritis in humans. However, the exact...

Sublethal Infection of C57BL/6 Mice with Salmonella enterica Serovar Typhimurium Leads to an Increase in Levels of Toll-Like Receptor 1 (TLR1), TLR2, and TLR9 mRNA as Well as a Decrease in Levels of TLR6 mRNA in Infected Organs

Tötemeyer, Sabine, Kaiser, Pete, Maskell, Duncan J., Bryant, Clare E.

Sublethal infection of C57BL/6 mice with Salmonella enterica serovar Typhimurium M525P initiates a strong inflammatory response. We measured organ expression of mRNA for Toll-like receptors and their...

Campylobacter jejuni-Induced Cytokine Responses in Avian Cells

Smith, Chris K., Kaiser, Pete, Rothwell, Lisa, Humphrey, Tom, Barrow, Paul A., Jones, Michael A.

Campylobacter jejuni is a major cause of human inflammatory enteritis. During the course of human disease numerous proinflammatory cytokines are produced. Little is known, however, about the cytokine...

Cytokine and Chemokine Responses Associated with Clearance of a Primary Salmonella enterica Serovar Typhimurium Infection in the Chicken and in Protective Immunity to Rechallenge

Withanage, G. S. K., Wigley, Paul, Kaiser, Pete, Mastroeni, Pietro, Brooks, Heather, Powers, Claire, ...

Infection of poultry with Salmonella enterica serovar Typhimurium poses a significant risk to public health through contamination of meat from infected animals. Vaccination has been proposed to...

A Strong Antigen-Specific T-Cell Response Is Associated with Age and Genetically Dependent Resistance to Avian Enteric Salmonellosis

Beal, Richard K., Powers, Claire, Wigley, Paul, Barrow, Paul A., Kaiser, Pete, Smith, Adrian L.

Chicken genetics and age affect resistance to enteric infection with Salmonella enterica serovar Typhimurium and were used to identify the immune responses that may contribute to rapid clearance....

Macrophages Isolated from Chickens Genetically Resistant or Susceptible to Systemic Salmonellosis Show Magnitudinal and Temporal Differential Expression of Cytokines and Chemokines following Salmonella enterica Challenge†

Wigley, Paul, Hulme, Scott, Rothwell, Lisa, Bumstead, Nat, Kaiser, Pete, Barrow, Paul

Macrophages from inbred chickens that are resistant to salmonellosis show greater and more rapid expression of proinflammatory chemokines and cytokines, including the key Th1-inducing cytokine...

Differential Cytokine Responses following Marek's Disease Virus Infection of Chickens Differing in Resistance to Marek's Disease

Kaiser, Pete, Underwood, Greg, Davison, Fred

The production of cytokine mRNAs, in addition to viral DNA, was quantified by real-time quantitative reverse transcription-PCR (RT-PCR) (cytokines) or PCR (virus) in splenocytes during the course of...

In Vitro and In Ovo Expression of Chicken Gamma Interferon by a Defective RNA of Avian Coronavirus Infectious Bronchitis Virus

Hackney, Karen, Cavanagh, Dave, Kaiser, Pete, Britton, Paul

Coronavirus defective RNAs (D-RNAs) have been used for site-directed mutagenesis of coronavirus genomes and for expression of heterologous genes. D-RNA CD-61 derived from the avian coronavirus...

Toll-Like Receptor Expression in C3H/HeN and C3H/HeJ Mice during Salmonella enterica Serovar Typhimurium Infection

Tötemeyer, Sabine, Foster, Neil, Kaiser, Pete, Maskell, Duncan J., Bryant, Clare E.

Here, we have investigated the mRNA expression of Toll-like receptor 2 (TLR-2), TLR-4, and MD-2 in spleens and livers of C3H/HeN mice (carrying wild-type TLR-4) and C3H/HeJ mice (carrying mutated...

Rapid Expression of Chemokines and Proinflammatory Cytokines in Newly Hatched Chickens Infected with Salmonella enterica Serovar Typhimurium

Withanage, G. S. K., Kaiser, Pete, Wigley, Paul, Powers, Claire, Mastroeni, Pietro, Brooks, Heather, ...

Poultry meat and eggs contaminated with Salmonella enterica serovar Enteritidis or Salmonella enterica serovar Typhimurium are common sources of acute gastroenteritis in humans. However, the exact...

Sublethal Infection of C57BL/6 Mice with Salmonella enterica Serovar Typhimurium Leads to an Increase in Levels of Toll-Like Receptor 1 (TLR1), TLR2, and TLR9 mRNA as Well as a Decrease in Levels of TLR6 mRNA in Infected Organs

Tötemeyer, Sabine, Kaiser, Pete, Maskell, Duncan J., Bryant, Clare E.

Sublethal infection of C57BL/6 mice with Salmonella enterica serovar Typhimurium M525P initiates a strong inflammatory response. We measured organ expression of mRNA for Toll-like receptors and their...

Campylobacter jejuni-Induced Cytokine Responses in Avian Cells

Smith, Chris K., Kaiser, Pete, Rothwell, Lisa, Humphrey, Tom, Barrow, Paul A., Jones, Michael A.

Campylobacter jejuni is a major cause of human inflammatory enteritis. During the course of human disease numerous proinflammatory cytokines are produced. Little is known, however, about the cytokine...

Cytokine and Chemokine Responses Associated with Clearance of a Primary Salmonella enterica Serovar Typhimurium Infection in the Chicken and in Protective Immunity to Rechallenge

Withanage, G. S. K., Wigley, Paul, Kaiser, Pete, Mastroeni, Pietro, Brooks, Heather, Powers, Claire, ...

Infection of poultry with Salmonella enterica serovar Typhimurium poses a significant risk to public health through contamination of meat from infected animals. Vaccination has been proposed to...

A Strong Antigen-Specific T-Cell Response Is Associated with Age and Genetically Dependent Resistance to Avian Enteric Salmonellosis

Beal, Richard K., Powers, Claire, Wigley, Paul, Barrow, Paul A., Kaiser, Pete, Smith, Adrian L.

Chicken genetics and age affect resistance to enteric infection with Salmonella enterica serovar Typhimurium and were used to identify the immune responses that may contribute to rapid clearance....

Macrophages Isolated from Chickens Genetically Resistant or Susceptible to Systemic Salmonellosis Show Magnitudinal and Temporal Differential Expression of Cytokines and Chemokines following Salmonella enterica Challenge†

Wigley, Paul, Hulme, Scott, Rothwell, Lisa, Bumstead, Nat, Kaiser, Pete, Barrow, Paul

Macrophages from inbred chickens that are resistant to salmonellosis show greater and more rapid expression of proinflammatory chemokines and cytokines, including the key Th1-inducing cytokine...

Differential cytokine mRNA expression in heterophils isolated from Salmonella-resistant and -susceptible chickens

Swaggerty, Christina L, Kogut, Michael H, Ferro, Pamela J, Rothwell, Lisa, Pevzner, Igal Y, Kaiser, Pete

We recently showed that increased in vitro heterophil functional efficiency translates to increased in vivo resistance to a systemic Salmonella enteritidis (SE) infection utilizing a parental pair of...

Embryonic age influences the capacity for cytokine induction in chicken thymocytes

Peters, Michelle A, Browning, Glenn F, Washington, Elizabeth A, Crabb, Brendan S, Kaiser, Pete

Thymocyte responses to functional activation are of relevance to the evaluation of the efficacy of in ovo immunotherapies and vaccines in chickens. In this study we have demonstrated differences in...

Protection of turkeys against Chlamydophila psittaci challenge by parenteral and mucosal inoculations and the effect of turkey interferon-γ on genetic immunization

VANROMPAY, DAISY, COX, ERIC, KAISER, PETE, LAWSON, SHELLY, VAN LOOCK, MARNIX, VOLCKAERT, GUIDO, ...

Plasmid DNA (pcDNA1::MOMP A) expressing the major outer membrane protein of an avian Chlamydophila psittaci serovar A strain was tested for its ability to induce protective immunity against challenge...

Upregulation of Cytokines Is Detected in the Placentas of Cattle Infected with Neospora caninum and Is More Marked Early in Gestation When Fetal Death Is Observed ▿

Rosbottom, Anne, Gibney, E. Helen, Guy, Catherine S., Kipar, Anja, Smith, Robert F., Kaiser, Pete, ...

The protozoan parasite Neospora caninum causes fetal death after experimental infection of pregnant cattle in early gestation, but the fetus survives a similar infection in late gestation. An...