Expression of IL-10 receptors on epithelial cells from the murine small and large intestine (2000)
Denning, Timothy L., Campbell, Nicola A., Song, Fei, Garofalo, Roberto P., Klimpel, Gary R., Reyes, Victor E., ...
The appearance of chronic intestinal inflammation in IL-10 knockout mice suggests IL-10 may inhibit adverse responses to luminal antigen. Moreover, this inflammation is associated with an increase in...
KAWABATA, THOMAS T., BURLESON, GARY R., ERNST, PETER B., ULLRICH, STEPHEN E.
The area of immunotoxicology has grown significantly over the past decade. Most of the research on methods development and validation and mechanisms of action have focused on the systemic immune...
Croitori, Kenneth, Blenenstock, John, Ernst, Peter B.
Differences in the surface antigen phenotype, such as the expression CD8 as an αα homodimer or the lack of Thy-1, on Intestinal Intraepithelial lymphocytes (IEL) are related, In part, to...
Transforming growth factor-{beta}1 enhances IgG and IgA sheep red blood cell responses (1992)
Zettel, Lenore, Clark, David A., Ernst, Peter B.
Antibody responses to ingested antigens can be inhibited by a mechanism known as oral tolerance which acts to prevent excessive stimulation from luminal contents. Local IgA responses can be induced...
Wang, Jide, Fan, Xuejun, Lindholm, Catharina, Bennett, Michael, O'Connoll, Joe, Shanahan, Fergus, ...
Helicobacter pylori causes a common chronic infection of humans that leads to epithelial cell damage. Studies have shown that apoptosis of the gastric epithelium is increased during infection and...
Helicobacter pylori Does Not Require Lewis X or Lewis Y Expression To Colonize C3H/HeJ mice
Takata, Tohru, El-Omar, Emad, Camorlinga, Margarita, Thompson, Stuart A., Minohara, Yutaka, Ernst, Peter B., ...
Helicobacter pylori strains frequently express Lewis X (Lex) and/or Ley on their cell surfaces as constituents of the O antigens of their lipopolysaccharide molecules. To assess the effect of Lex and...
Haeberle, Helene A., Casola, Antonella, Gatalica, Zoran, Petronella, Sharon, Dieterich, Hans-Juergen, Ernst, Peter B., ...
Respiratory syncytial virus (RSV) is the major etiologic agent of severe epidemic lower respiratory tract infections in infancy. Airway mucosal inflammation plays a critical role in the pathogenesis...
Ryan, Kieran A., Smith, Michael F., Sanders, Michael K., Ernst, Peter B.
Toll-like receptor 4 (TLR4) has been identified as a transmembrane protein involved in the host innate immune response to gram-negative bacterial lipopolysaccharide (LPS). Upon activation by LPS...
Olson, Timothy S., Bamias, Giorgos, Naganuma, Makoto, Rivera-Nieves, Jesús, Burcin, Tracy L., Ross, William, ...
SAMP1/YitFc mice develop discontinuous, transmural inflammatory lesions in the terminal ileum, similar to what is found in human Crohn disease. Compared with the mesenteric lymph nodes (MLNs) of AKR...
B-Cell and T-Cell Immune Responses to Experimental Helicobacter pylori Infection in Humans
Nurgalieva, Zhannat Z., Conner, Margaret E., Opekun, Antone R., Zheng, Carl Q., Elliott, Susan N., Ernst, Peter B., ...
The acute antibody and T-cell immune response to Helicobacter pylori infection in humans has not been studied systematically. Serum from H. pylori-naive volunteers challenged with H. pylori and cured...
Wang, Jide, Fan, Xuejun, Lindholm, Catharina, Bennett, Michael, O'Connoll, Joe, Shanahan, Fergus, ...
Helicobacter pylori causes a common chronic infection of humans that leads to epithelial cell damage. Studies have shown that apoptosis of the gastric epithelium is increased during infection and...
Helicobacter pylori Does Not Require Lewis X or Lewis Y Expression To Colonize C3H/HeJ mice
Takata, Tohru, El-Omar, Emad, Camorlinga, Margarita, Thompson, Stuart A., Minohara, Yutaka, Ernst, Peter B., ...
Helicobacter pylori strains frequently express Lewis X (Lex) and/or Ley on their cell surfaces as constituents of the O antigens of their lipopolysaccharide molecules. To assess the effect of Lex and...
Haeberle, Helene A., Casola, Antonella, Gatalica, Zoran, Petronella, Sharon, Dieterich, Hans-Juergen, Ernst, Peter B., ...
Respiratory syncytial virus (RSV) is the major etiologic agent of severe epidemic lower respiratory tract infections in infancy. Airway mucosal inflammation plays a critical role in the pathogenesis...
Ryan, Kieran A., Smith, Michael F., Sanders, Michael K., Ernst, Peter B.
Toll-like receptor 4 (TLR4) has been identified as a transmembrane protein involved in the host innate immune response to gram-negative bacterial lipopolysaccharide (LPS). Upon activation by LPS...
Olson, Timothy S., Bamias, Giorgos, Naganuma, Makoto, Rivera-Nieves, Jesús, Burcin, Tracy L., Ross, William, ...
SAMP1/YitFc mice develop discontinuous, transmural inflammatory lesions in the terminal ileum, similar to what is found in human Crohn disease. Compared with the mesenteric lymph nodes (MLNs) of AKR...
B-Cell and T-Cell Immune Responses to Experimental Helicobacter pylori Infection in Humans
Nurgalieva, Zhannat Z., Conner, Margaret E., Opekun, Antone R., Zheng, Carl Q., Elliott, Susan N., Ernst, Peter B., ...
The acute antibody and T-cell immune response to Helicobacter pylori infection in humans has not been studied systematically. Serum from H. pylori-naive volunteers challenged with H. pylori and cured...
Croxen, Matthew A., Ernst, Peter B., Hoffman, Paul S.
Much of the gene content of the human gastric pathogen Helicobacter pylori (∼1.7-Mb genome) is considered essential. This view is based on the completeness of metabolic pathways, infrequency of...
Ding, Song-Ze, Minohara, Yutaka, Fan, Xue Jun, Wang, Jide, Reyes, Victor E., Patel, Janak, ...
Helicobacter pylori infection is associated with altered gastric epithelial cell turnover. To evaluate the role of oxidative stress in cell death, gastric epithelial cells were exposed to various...
The primary defect in experimental ileitis originates from a nonhematopoietic source
Olson, Timothy S., Reuter, Brian K., Scott, Kevin G-E., Morris, Margaret A., Wang, Xiao-Ming, Hancock, Leslie N., ...
The initiating etiologic factor in Crohn's disease (CD) remains unclear. SAMP1/YitFc (SAMP) mice develop chronic ileitis similar to human CD. We used bone marrow chimeras to determine if SAMP ileitis...
Fan, Xuejun, Crowe, Sheila E., Behar, Simon, Gunasena, Harshani, Ye, Gang, Haeberle, Helene, ...
Helicobacter pylori infection is associated with gastric epithelial damage, including apoptosis, ulceration, and cancer. Although bacterial factors and the host response are believed to contribute to...