The vanC-3 vancomycin resistance gene cluster of Enterococcus flavescens CCM 439 (2003)
Dutta, Ireena, Reynolds, Peter E.
Enterococcus flavescens CCM 439 is phenotypically similar to Enterococcus casseliflavus; it possesses intrinsic low-level resistance to vancomycin and has the VanC phenotype. The complete vanC-3...
The vanC-3 vancomycin resistance gene cluster of Enterococcus flavescens CCM 439 (2003)
Dutta, Ireena, Reynolds, Peter E.
Enterococcus flavescens CCM 439 is phenotypically similar to Enterococcus casseliflavus; it possesses intrinsic low-level resistance to vancomycin and has the VanC phenotype. The complete vanC-3...
The vanC-3 vancomycin resistance gene cluster of Enterococcus flavescens CCM 439 (2003)
Dutta, Ireena, Reynolds, Peter E.
Enterococcus flavescens CCM 439 is phenotypically similar to Enterococcus casseliflavus; it possesses intrinsic low-level resistance to vancomycin and has the VanC phenotype. The complete vanC-3...
Vancomycin-Dependent Enterococcus faecalis Clinical Isolates and Revertant Mutants
Van Bambeke, Françoise, Chauvel, Murielle, Reynolds, Peter E., Fraimow, Henry S., Courvalin, Patrice
Three vancomycin-dependent clinical isolates of Enterococcus faecalis of the VanB type were studied by determining (i) the sequence of the ddl gene encoding the host d-Ala:d-Ala ligase and the...
vanC Cluster of Vancomycin-Resistant Enterococcus gallinarum BM4174
Arias, Cesar A., Courvalin, Patrice, Reynolds, Peter E.
Glycopeptide-resistant enterococci of the VanC type synthesize UDP-muramyl-pentapeptide[d-Ser] for cell wall assembly and prevent synthesis of peptidoglycan precursors ending in d-Ala. The vanC...
Dalla Costa, Libera M., Reynolds, Peter E., Souza, Helena A. P. H. M., Souza, Dilair C., Palepou, Marie-France I., Woodford, Neil
Enterococcus faecium 10/96A from Brazil was resistant to vancomycin (MIC, 256 μg/ml) but gave no amplification products with primers specific for known van genotypes. A 2,368-bp fragment of a van...
Casadewall, Barbara, Reynolds, Peter E., Courvalin, Patrice
A new open reading frame, encoding a putative integrase-like protein, was detected downstream from the six genes of the vanD glycopeptide resistance cluster in Enterococcus faecium BM4339 (B....
The Lantibiotic Mersacidin Inhibits Peptidoglycan Synthesis by Targeting Lipid II
Brötz, Heike, Bierbaum, Gabriele, Leopold, Klaus, Reynolds, Peter E., Sahl, Hans-Georg
The lantibiotic mersacidin exerts its bactericidal action by inhibition of peptidoglycan biosynthesis. It interferes with the membrane-associated transglycosylation reaction; during this step the...
Ambúr, Ole-Herman, Reynolds, Peter E., Arias, Cesar A.
An open reading frame located 230 nucleotides downstream from the stop codon of vanSc and in the opposite direction relative to the other genes of the vanC cluster was identified in Enterococcus...
Dutta, Ireena, Reynolds, Peter E.
The vanC-2 cluster of Enterococcus casseliflavus ATCC 25788 consisted of five genes (vanC-2, vanXYC-2, vanTC-2, vanRC-2, and vanSC-2) and shared the same organization as the vanC cluster of E....
VanD-Type Vancomycin-Resistant Enterococcus faecium 10/96A
Depardieu, Florence, Reynolds, Peter E., Courvalin, Patrice
VanD type Enterococcus faecium 10/96A is constitutively resistant to vancomycin and to low levels of teicoplanin by nearly exclusive synthesis of peptidoglycan precursors terminating in...
Vancomycin Resistance in Enterococci Due to Synthesis of Precursors Terminating in d-Alanyl-d-Serine
Panesso, Diana, Abadía-Patiño, Lorena, Vanegas, Natasha, Reynolds, Peter E., Courvalin, Patrice, Arias, Cesar A.
The vanC glycopeptide resistance gene cluster encodes enzymes required for synthesis of peptidoglycan precursors ending in d-Ala-d-Ser. Enterococcus gallinarum BM4174 and SC1 are constitutively and...
Frère, Jean-Marie, Ghuysen, Jean-Marie, Reynolds, Peter E., Moreno, Ramon, Perkins, Harold R.
Benzylpenicillin and cephaloridine reacted with the exocellular dd-carboxypeptidase–transpeptidase from Streptomyces R39 to form equimolar and inactive antibiotic–enzyme complexes. At saturation,...
Vancomycin-Dependent Enterococcus faecalis Clinical Isolates and Revertant Mutants
Van Bambeke, Françoise, Chauvel, Murielle, Reynolds, Peter E., Fraimow, Henry S., Courvalin, Patrice
Three vancomycin-dependent clinical isolates of Enterococcus faecalis of the VanB type were studied by determining (i) the sequence of the ddl gene encoding the host d-Ala:d-Ala ligase and the...
vanC Cluster of Vancomycin-Resistant Enterococcus gallinarum BM4174
Arias, Cesar A., Courvalin, Patrice, Reynolds, Peter E.
Glycopeptide-resistant enterococci of the VanC type synthesize UDP-muramyl-pentapeptide[d-Ser] for cell wall assembly and prevent synthesis of peptidoglycan precursors ending in d-Ala. The vanC...
Dalla Costa, Libera M., Reynolds, Peter E., Souza, Helena A. P. H. M., Souza, Dilair C., Palepou, Marie-France I., Woodford, Neil
Enterococcus faecium 10/96A from Brazil was resistant to vancomycin (MIC, 256 μg/ml) but gave no amplification products with primers specific for known van genotypes. A 2,368-bp fragment of a van...
Casadewall, Barbara, Reynolds, Peter E., Courvalin, Patrice
A new open reading frame, encoding a putative integrase-like protein, was detected downstream from the six genes of the vanD glycopeptide resistance cluster in Enterococcus faecium BM4339 (B....
The Lantibiotic Mersacidin Inhibits Peptidoglycan Synthesis by Targeting Lipid II
Brötz, Heike, Bierbaum, Gabriele, Leopold, Klaus, Reynolds, Peter E., Sahl, Hans-Georg
The lantibiotic mersacidin exerts its bactericidal action by inhibition of peptidoglycan biosynthesis. It interferes with the membrane-associated transglycosylation reaction; during this step the...
Ambúr, Ole-Herman, Reynolds, Peter E., Arias, Cesar A.
An open reading frame located 230 nucleotides downstream from the stop codon of vanSc and in the opposite direction relative to the other genes of the vanC cluster was identified in Enterococcus...
Dutta, Ireena, Reynolds, Peter E.
The vanC-2 cluster of Enterococcus casseliflavus ATCC 25788 consisted of five genes (vanC-2, vanXYC-2, vanTC-2, vanRC-2, and vanSC-2) and shared the same organization as the vanC cluster of E....
VanD-Type Vancomycin-Resistant Enterococcus faecium 10/96A
Depardieu, Florence, Reynolds, Peter E., Courvalin, Patrice
VanD type Enterococcus faecium 10/96A is constitutively resistant to vancomycin and to low levels of teicoplanin by nearly exclusive synthesis of peptidoglycan precursors terminating in...
Vancomycin Resistance in Enterococci Due to Synthesis of Precursors Terminating in d-Alanyl-d-Serine
Panesso, Diana, Abadía-Patiño, Lorena, Vanegas, Natasha, Reynolds, Peter E., Courvalin, Patrice, Arias, Cesar A.
The vanC glycopeptide resistance gene cluster encodes enzymes required for synthesis of peptidoglycan precursors ending in d-Ala-d-Ser. Enterococcus gallinarum BM4174 and SC1 are constitutively and...
Frère, Jean-Marie, Ghuysen, Jean-Marie, Reynolds, Peter E., Moreno, Ramon, Perkins, Harold R.
Benzylpenicillin and cephaloridine reacted with the exocellular dd-carboxypeptidase–transpeptidase from Streptomyces R39 to form equimolar and inactive antibiotic–enzyme complexes. At saturation,...