Analysis of the largest tandemly repeated DNA families in the human genome (2008)
Warburton, Peter E, Hasson, Dan, Guillem, Flavia, Lescale, Chloe, Jin, Xiaoping, Abrusan, Gyorgy
Abstract Background Tandemly Repeated DNA represents a large portion of the human genome, and accounts for a significant amount of copy number variation. Here we present a genome wide analysis of the...
Biased distributions and decay of long interspersed nuclear elements in the chicken genome (2008)
Abrusán, György, Krambeck, Hans-Jürgen, Junier, Thomas, Giordano, Joti, Warburton, Peter E.
The genomes of birds are much smaller than mammalian genomes, and transposable elements (TEs) make up only 10% of the chicken genome, compared with the 45% of the human genome. To study the...
Alonso, Alicia, Fritz, Björn, Hasson, Dan, Abrusan, György, Cheung, Fanny, Yoda, Kinya, ...
Abstract Background Mammalian centromere formation is dependent on chromatin that contains centromere protein (CENP)-A, which is the centromere-specific histone H3 variant. Human neocentromeres have...
Evolutionary History of Mammalian Transposons Determined by Genome-Wide Defragmentation (2007)
Joti Giordano, Yongchao Ge, Yevgeniy Gelfand, György Abrusán, Gary Benson, Peter E. Warburton
The constant bombardment of mammalian genomes by transposable elements (TEs) has resulted in TEs comprising at least 45% of the human genome. Because of their great age and abundance, TEs are...
Evolutionary History of Mammalian Transposons Determined by Genome-wide Defragmentation (2007)
Joti Giordano, Yongchao Ge, Yevgeniy Gelfand, Gyorgy Abrusan, Gary Benson, Peter E. Warburton
The constant bombardment of mammalian genomes by Transposable Elements (TEs) has resulted in TEs comprising at least 45% of the human genome. Because of their great age and abundance, TEs are...
Cardone, Maria, Alonso, Alicia, Pazienza, Michele, Ventura, Mario, Montemurro, Gabriella, Carbone, Lucia, ...
Abstract Background Evolutionary centromere repositioning and human analphoid neocentromeres occurring in clinical cases are, very likely, two stages of the same phenomenon whose properties still...
Warburton, Peter E., Giordano, Joti, Cheung, Fanny, Gelfand, Yefgeniy, Benson, Gary
We have performed the first genome-wide analysis of the Inverted Repeat (IR) structure in the human genome, using a novel and efficient software package called Inverted Repeats Finder (IRF). After...
DNA modi®cation and functional delivery into human cells using Escherichia coli DH10B (2003)
Kumaran Narayanan, Peter E. Warburton
The availability of almost the complete human genome as cloned BAC libraries represents a valuable resource for functional genomic analysis, which, however, has been somewhat limited by the ability...
Alonso, Alicia, Mahmood, Radma, Li, Shulan, Cheung, Fanny, Yoda, Kinya, Warburton, Peter E.
Human neocentromeres are fully functional centromeres that provide mitotic stability to rearranged chromosomes that have separated from endogenous centromeres. A disproportionate number of...
DNA modification and functional delivery into human cells using Escherichia coli DH10B (2003)
Narayanan, Kumaran, Warburton, Peter E.
The availability of almost the complete human genome as cloned BAC libraries represents a valuable resource for functional genomic analysis, which, however, has been somewhat limited by the ability...
Alonso, Alicia, Mahmood, Radma, Li, Shulan, Cheung, Fanny, Yoda, Kinya, Warburton, Peter E.
Human neocentromeres are fully functional centromeres that provide mitotic stability to rearranged chromosomes that have separated from endogenous centromeres. A disproportionate number of...
Alonso, Alicia, Mahmood, Radma, Li, Shulan, Cheung, Fanny, Yoda, Kinya, Warburton, Peter E.
Human neocentromeres are fully functional centromeres that provide mitotic stability to rearranged chromosomes that have separated from endogenous centromeres. A disproportionate number of...
Sugata, Naoko, Li, Shulan, Earnshaw, William C., Yen, Tim J., Yoda, Kinya, Masumoto, Hiroshi, ...
Centromere and kinetochore proteins have a pivotal role in centromere structure, kinetochore formation and sister chromatid separation. However, the molecular architecture and the precise dynamic...
Warburton, Peter E., Willard, Huntington F.
Tandemly repeated DNA can comprise several percent of total genomic DNA in complex organisms and, in some instances, may play a role in chromosome structure or function. Alpha satellite DNA is the...
DNA modification and functional delivery into human cells using Escherichia coli DH10B
Narayanan, Kumaran, Warburton, Peter E.
The availability of almost the complete human genome as cloned BAC libraries represents a valuable resource for functional genomic analysis, which, however, has been somewhat limited by the ability...
Warburton, Peter E., Giordano, Joti, Cheung, Fanny, Gelfand, Yefgeniy, Benson, Gary
We have performed the first genome-wide analysis of the Inverted Repeat (IR) structure in the human genome, using a novel and efficient software package called Inverted Repeats Finder (IRF). After...
DNA modification and functional delivery into human cells using Escherichia coli DH10B
Narayanan, Kumaran, Warburton, Peter E.
The availability of almost the complete human genome as cloned BAC libraries represents a valuable resource for functional genomic analysis, which, however, has been somewhat limited by the ability...
Warburton, Peter E., Giordano, Joti, Cheung, Fanny, Gelfand, Yefgeniy, Benson, Gary
We have performed the first genome-wide analysis of the Inverted Repeat (IR) structure in the human genome, using a novel and efficient software package called Inverted Repeats Finder (IRF). After...
Cardone, Maria Francesca, Alonso, Alicia, Pazienza, Michele, Ventura, Mario, Montemurro, Gabriella, Carbone, Lucia, ...
The mammalian evolutionary history of chromosome 13 was characterized and evolutionary-new centromeres compared to two human neocentromeres at 13q21 using chromatin immunoprecipitation and genomic...
Evolutionary History of Mammalian Transposons Determined by Genome-Wide Defragmentation
Giordano, Joti, Ge, Yongchao, Gelfand, Yevgeniy, Abrusán, György, Benson, Gary, Warburton, Peter E
The constant bombardment of mammalian genomes by transposable elements (TEs) has resulted in TEs comprising at least 45% of the human genome. Because of their great age and abundance, TEs are...
Biased Distributions and Decay of Long Interspersed Nuclear Elements in the Chicken Genome
Abrusán, György, Krambeck, Hans-Jürgen, Junier, Thomas, Giordano, Joti, Warburton, Peter E.
The genomes of birds are much smaller than mammalian genomes, and transposable elements (TEs) make up only 10% of the chicken genome, compared with the 45% of the human genome. To study the...
Alonso, Alicia, Fritz, Björn, Hasson, Dan, Abrusan, György, Cheung, Fanny, Yoda, Kinya, ...
The distribution of centromeric chromatin-associated proteins across human neocentromeric DNA shows that this chromatin consists of several CENP-A-containing sub-domains.
Analysis of Transposon Interruptions Suggests Selection for L1 Elements on the X Chromosome
Abrusán, György, Giordano, Joti, Warburton, Peter E.
It has been hypothesised that the massive accumulation of L1 transposable elements on the X chromosome is due to their function in X inactivation, and that the accumulation of Alu elements near genes...