Peter Frederik

Protocols for the EM study of liver tissue and cells (2009)

Braet, Filip, Duimel, Hans, Vreuls, Celien, Koek, Ger, Olde Damink, Steven, ...

Increased expression of rapsyn in muscles prevents acetylcholine receptor loss in experimental autoimmune myasthenia gravis (2005)

Losen, Mario, Stassen, Maurice H. W., Martínez-Martínez, Pilar, Machiels, Barbie M., Duimel, Hans, Frederik, Peter, ...

Myasthenia gravis is usually caused by autoantibodies to the acetylcholine receptor (AChR). The AChR is clustered and anchored in the postsynaptic membrane of the neuromuscular junction (NMJ) by a...

Increased expression of rapsyn in muscles prevents acetylcholine receptor loss in experimental autoimmune myasthenia gravis (2005)

Losen, Mario, Stassen, Maurice H. W., Martínez-Martínez, Pilar, Machiels, Barbie M., Duimel, Hans, Frederik, Peter, ...

Myasthenia gravis is usually caused by autoantibodies to the acetylcholine receptor (AChR). The AChR is clustered and anchored in the postsynaptic membrane of the neuromuscular junction (NMJ) by a...

Mild Heating of Amphotericin B-Desoxycholate: Effects on Ultrastructure, In Vitro Activity and Toxicity, and Therapeutic Efficacy in Severe Candidiasis in Leukopenic Mice

Van Vianen, Wim, Roovers, Patty, Frederik, Peter

Heated (20 min at 70°C) amphotericin B-desoxycholate (hAMB-DOC) was further characterized, as was another formulation obtained after centrifugation (60 min, 3000 × g), hcAMB-DOC. Conventional...

Osmotic and curvature stress affect PEG-induced fusion of lipid vesicles but not mixing of their lipids.

Malinin, Vladimir S, Frederik, Peter, Lentz, Barry R

Poly (ethylene glycol) (PEG) in the external environment of membrane vesicles creates osmotic imbalance that leads to mechanical stress in membranes and may induce local membrane curvature. To...

Mild Heating of Amphotericin B-Desoxycholate: Effects on Ultrastructure, In Vitro Activity and Toxicity, and Therapeutic Efficacy in Severe Candidiasis in Leukopenic Mice

Van Vianen, Wim, Roovers, Patty, Frederik, Peter

Heated (20 min at 70°C) amphotericin B-desoxycholate (hAMB-DOC) was further characterized, as was another formulation obtained after centrifugation (60 min, 3000 × g), hcAMB-DOC. Conventional...

Osmotic and curvature stress affect PEG-induced fusion of lipid vesicles but not mixing of their lipids.

Malinin, Vladimir S, Frederik, Peter, Lentz, Barry R

Poly (ethylene glycol) (PEG) in the external environment of membrane vesicles creates osmotic imbalance that leads to mechanical stress in membranes and may induce local membrane curvature. To...

Overexpression of Rapsyn in Rat Muscle Increases Acetylcholine Receptor Levels in Chronic Experimental Autoimmune Myasthenia Gravis

Martínez-Martínez, Pilar, Losen, Mario, Duimel, Hans, Frederik, Peter, Spaans, Frank, Molenaar, Peter, ...

The primary autoantigen in myasthenia gravis, the acetylcholine receptor (AChR), is clustered and anchored in the postsynaptic membrane of the neuromuscular junction by rapsyn. Previously, we found...

Silencing rapsyn in vivo decreases acetylcholine receptors and augments sodium channels and secondary postsynaptic membrane folding

Martinez-Martinez, Pilar, Phemambucq, Marko, Steinbusch, Laura, Schaeffer, Laurent, Berrih-Aknin, Sonia, Duimel, Hans, ...

The receptor-associated protein of the synapse (rapsyn) is required for anchoring and stabilizing the nicotinic acetylcholine receptor (AChR) in the postsynaptic membrane of the neuromuscular...

Silencing rapsyn in vivo decreases acetylcholine receptors and augments sodium channels and secondary postsynaptic membrane folding

Martinez-Martinez, Pilar, Phemambucq, Marko, Steinbusch, Laura, Schaeffer, Laurent, Berrih-Aknin, Sonia, Duimel, Hans, ...

The receptor-associated protein of the synapse (rapsyn) is required for anchoring and stabilizing the nicotinic acetylcholine receptor (AChR) in the postsynaptic membrane of the neuromuscular...