Peter M. P. Lanigan

Fluorescence Lifetime Imaging Provides Enhanced Contrast when Imaging the Phase-Sensitive Dye di-4-ANEPPDHQ in Model Membranes and Live Cells

Owen, Dylan M., Lanigan, Peter M. P., Dunsby, Christopher, Munro, Ian, Grant, David, Neil, Mark A. A., ...

We apply fluorescence lifetime imaging to the membrane phase-sensing dye di-4-ANEPPDHQ in model membranes and live cells. We show that the 1700 ps lifetime shift between liquid-disordered and...

Microclusters of inhibitory killer immunoglobulin–like receptor signaling at natural killer cell immunological synapses

Treanor, Bebhinn, Lanigan, Peter M.P., Kumar, Sunil, Dunsby, Chris, Munro, Ian, Auksorius, Egidijus, ...

We report the supramolecular organization of killer Ig–like receptor (KIR) phosphorylation using a technique applicable to imaging phosphorylation of any green fluorescent protein–tagged receptor...