Multi-tissue gene-expression analysis in a mouse model of thyroid hormone resistance (2004)
Miller, Lance D, McPhie, Peter, Suzuki, Hideyo, Kato, Yasuhito, Liu, Edison T, Cheng, Sheue-yann
Abstract Background Resistance to thyroid hormone (RTH) is caused by mutations of the thyroid hormone receptor β (TRβ) gene. To understand the transcriptional program underlying TRβ mutant-induced...
Kamiya, Yuji, Puzianowska-Kuznicka, Monika, McPhie, Peter, Nauman, Janusz, Cheng, Sheue-yann, Nauman, Alicja
Thyroid hormone (T3) regulates proliferation and differentiation of cells, via its nuclear receptors (TRs). These processes have been shown to be abnormally regulated during carcinogenesis. We have...
Zhu, Xu-guang, Park, Kyung Soo, Kaneshige, Masahiro, Bhat, Manoj K., Zhu, Qihong, Mariash, Cary N., ...
Thyroid hormone (T3) nuclear receptors (TR) are ligand-dependent transcription factors which regulate growth, differentiation, and development. One emerging hypothesis suggests that TR mediate these...
Multi-tissue gene-expression analysis in a mouse model of thyroid hormone resistance
Miller, Lance D, McPhie, Peter, Suzuki, Hideyo, Kato, Yasuhito, Liu, Edison T, Cheng, Sheue-yann
Gene-expression analysis in cerebellum, heart and white adipose tissue from a knock-in mouse that harbors a human mutation and faithfully reproduces human resistance to thyroid hormone, uncovered...
Jang, Ming Y., Yarborough, OrLando H., Conyers, Gary B., McPhie, Peter, Owens, Roland A.
Adeno-associated virus serotype 2 (AAV-2) can preferentially integrate its DNA into a 4-kb region of human chromosome 19, designated AAVS1. The nicking activity of AAV-2's Rep68 or Rep78 proteins is...
Thiol–disulphide interchange in tubulin: kinetics and the effect on polymerization
Britto, P. J., Knipling, Leslie, Mcphie, Peter, Wolff, J.
All 20 cysteine residues are accessible to disulphide reagents in the tubulin dimer, whereas only four are accessible in taxol-stabilized microtubules. Reaction rates with disulphide reagents are a...
Zhu, Xu-guang, Park, Kyung Soo, Kaneshige, Masahiro, Bhat, Manoj K., Zhu, Qihong, Mariash, Cary N., ...
Thyroid hormone (T3) nuclear receptors (TR) are ligand-dependent transcription factors which regulate growth, differentiation, and development. One emerging hypothesis suggests that TR mediate these...
Multi-tissue gene-expression analysis in a mouse model of thyroid hormone resistance
Miller, Lance D, McPhie, Peter, Suzuki, Hideyo, Kato, Yasuhito, Liu, Edison T, Cheng, Sheue-yann
Gene-expression analysis in cerebellum, heart and white adipose tissue from a knock-in mouse that harbors a human mutation and faithfully reproduces human resistance to thyroid hormone, uncovered...
Jang, Ming Y., Yarborough, OrLando H., Conyers, Gary B., McPhie, Peter, Owens, Roland A.
Adeno-associated virus serotype 2 (AAV-2) can preferentially integrate its DNA into a 4-kb region of human chromosome 19, designated AAVS1. The nicking activity of AAV-2's Rep68 or Rep78 proteins is...
Thiol–disulphide interchange in tubulin: kinetics and the effect on polymerization
Britto, P. J., Knipling, Leslie, Mcphie, Peter, Wolff, J.
All 20 cysteine residues are accessible to disulphide reagents in the tubulin dimer, whereas only four are accessible in taxol-stabilized microtubules. Reaction rates with disulphide reagents are a...
Assembly of the Yeast Cell Wall: Crh1p AND Crh2p ACT AS TRANSGLYCOSYLASES IN VIVO AND IN VITRO*S⃞
Cabib, Enrico, Farkas, Vladimir, Kosík, Ondrej, Blanco, Noelia, Arroyo, Javier, McPhie, Peter
The cross-linking of polysaccharides to assemble new cell wall in fungi requires mechanisms by which a preexisting linkage is broken for each new one made, to allow for the absence of free energy...