Renner, Marcus, Bergmann, Gaby, Krebs, Inge, End, Caroline, Lyer, Stefan, Hilberg, Frank, ...
BACKGROUND & AIMS: Impaired mucosal defense plays an important role in the pathogenesis of Crohn's disease (CD), one of the main subtypes of inflammatory bowel disease (IBD). Deleted in malignant...
The systematic functional characterisation of Xq28 genes prioritises candidate disease genes (2006)
Kolb-Kokocinski, Anja, Mehrle, Alexander, Bechtel, Stephanie, Simpson, Jeremy C, Kioschis, Petra, Wiemann, Stefan, ...
Abstract Background Well known for its gene density and the large number of mapped diseases, the human sub-chromosomal region Xq28 has long been a focus of genome research. Over 40 of approximately...
Schneider, Jörg, Buneß, Andreas, Huber, Wolfgang, Volz, Joachim, Kioschis, Petra, Hafner, Mathias, ...
Abstract Background The requirement of a large amount of high-quality RNA is a major limiting factor for microarray experiments using biopsies. An average microarray experiment requires 10–100 μg...
Wirth, Jutta, Back, Elke, Hüttenhofer, Alexander, Nothwang, Hans-Gerd, Lich, Christina, Gross, Stephanie, ...
Balanced translocations affecting the paternal copy of 15q11–q13 are a rare cause of Prader–Willi syndrome (PWS) or PWS-like features. Here we report on the cytogenetic and molecular...
Kaiserslautern, Univ., Diss., 1994.
A YAC clone map spanning 7.5 megabases of human chromosome band Xq28 (1994)
Rogner, Ute C., Kioschis, Petra, Wilke, Klaus, Gong, Wellong, Pick, Elke, Dietrich, Alexander, ...
Xq28 has been of special Interest in human genetics because a large number of diseases map to this region. As a step In the molecular analysis of the as yet uncloned disease genes, and as a test for...
Sediacek, Zdenek, Korn, Bernhard, Konecki, David S., Siebenhaar, Renate, Coy, Johannes F., Kioschis, Petra, ...
A transcription map covering a 300 kb region around the G6PD gene in the human Xq28 region was constructed by the direct cDNA selection method and the analysis of the resulting region-specific...
Direct selection of DNA sequences conserved between species (1993)
Sedlacek, Zdenek, Konecki, David S., Siebenhaar, Renate, Kioschis, Petra, Poustka, Annemarie
An essential requirement in the analysis of genomes is the identification of functionally important sequence elements, which are often evolutionarily conserved. We describe here the development of a...
A strategy for the selection of transcribed sequences in the Xq28 region (1992)
Korn, Bernhard, Sedlacek, Zdenek, Manca, Antonella, Kioschis, Petra, Konecki, David, Lehrach, Hans, ...
As an essential step towards an exhaustive analysis of the coding potential of large regions of the genome, we have developed a protocol allowing the rapid isolation of transcripts defmed by...
Identification and characterization of a new gene in the human Xq28 region (1992)
Kioschis, Petra, Verdijk, Marian, Tamanini, Filippo, Toniolo, Daniela, Poustka, Annemarie, ...
A human Xqter chromosome cosmid library was screened with a mixed probe derived from porcine kidney mRNA. A new expressed gene was identified in a cosmid clone known to be part of a G6pd cosmid...
Maestrini, Elena, Tamanini, Filippo, Kioschis, Petra, Gimbo, Elisabeth, Marinelli, Paola, Tribioli, Carla, ...
19 probes for CpG islands, mapping Xq28, have been used as probes to construct a physical map of genes of this band of the human X chromosome. A total of 22 CpG islands have been precisely mapped in...
Molecular cloning and analysis of the fragile X region in man (1991)
Dietrich, Alexander, Kioschis, Petra, Monaco, Anthony P., Gross, Baerbel, Korn, Bernhard, Williams, Sarah V., ...
The fragile X syndrome (FraX), the most common Inherited form of mental retardation, has been located to Xq27.3. As a step In the molecular analysis of this mutation, we have cloned a contiguous 1.8...
Schneider, Jörg, Buneß, Andreas, Huber, Wolfgang, Volz, Joachim, Kioschis, Petra, Hafner, Mathias, ...
The systematic functional characterisation of Xq28 genes prioritises candidate disease genes
Kolb-Kokocinski, Anja, Mehrle, Alexander, Bechtel, Stephanie, Simpson, Jeremy C, Kioschis, Petra, Wiemann, Stefan, ...