Mathur, Shawn, Schmidt, Christian, Das, Chhaya, Tucker, Philip W
Abstract Uncensored exchange of scientific results hastens progress. Open Access does not stop at the removal of price and permission barriers; still, censorship and reading disabilities, to name a...
Brown, Mark A, Sims, Robert J, Gottlieb, Paul D, Tucker, Philip W
Abstract Background Disrupting the balance of histone lysine methylation alters the expression of genes involved in tumorigenesis including proto-oncogenes and cell cycle regulators. Methylation of...
Liu, Hui, Ippolito, Gregory C, Wall, Jason K, Niu, Teresa, Probst, Loren, Lee, Baeck-Seung, ...
Abstract Background Chromosomal aberrations of BCL11A at 2p16.1 have been reported in a variety of B-cell malignancies and its deficiency in mice leads to a profound block in B-cell development....
Ippolito, Gregory C, Schmidt, Christian, Das, Chhaya, Tucker, Philip W
No abstract available.
Kenny, James J., Derby, Eric G., Yoder, Jeffrey A., Hill, Shawn A., Fischer, Randy T., Tucker, Philip W., ...
Four variant forms of the V1 (T15-H chain) gene are synthesized in mice. Each V1 variant pairs with a distinct L chain to produce a binding site having specificity for phosphocholine (PC). Transgenic...
Production and characterization of recombinant human Ku antigen (1994)
Ono, Masashi, Tucker, Philip W., Capra, J.Donald
Ku is an ubiquitous nuclear heterodimeric protein consisting of p70 and p86 subunits that binds doublestranded DNA termini and associates with chromosomes in vivo. It was originally described as an...
Exoquence DNA sequencing (1993)
We have developed a strategy for DNA sequencing based on exonuclease III digestion followed by double strand specific endonuclease digestion and direct dideoxynucleotide sequencing reaction. This...
Moore, Bethany Beilue, Tan, Jing, Lim, Pak-Leung, Tucker, Philip W., Yuna, Dorothy
Previous experiments have shown that the extent of δ gene transcription during B cell development is regulated primarily at the transcriptlonal level. We have shown that deletion of a sequence...
Construction of recombinant DNA by exonuclease recession (1993)
Yang, Yih-Sheng, Watson, William J., Tucker, Philip W., Capra, J. Donald
We describe a new exonuclease-based method for joining and/or constructing two or more DNA molecules. DNA fragments containing ends complementary to those of a vector or another independent molecules...
Word, Charlotte J., White, Marga B., Kuzlel, William A., Shen, Anna L., Blattner, Frederick R., Tucker, Philip W., ...
The entire nucleotide sequence ({small tilde}20 kbp) spanning the human immunogiobulin IgM (μ) and IgD (δ) heavy chain constant region genes has been determined from DNA of μ–δ producing...
Kuziel, William A., Word, Charlotte J., Yuan, Dorothy, White, Marga B., Mushinski, J. Fredrick, Blattner, Frederick R., ...
Whether the immunoglobulln (Ig) heavy chain genes Cμ and Cδ are expressed singly or in combination, their transcripts undergo differentiation-specific alterations in membrane (M) versus secreted...
Landolfi, Nicholas F., Yin, Xiao-Ming, Capra, J.Donald, Tucker, Philip W.
Immunoglobulin genes contain a conserved eight base sequence element 5′ to the site of transcription initiation. This octamer can serve as a site for the binding of nuclear proteins which are...
Wang, Zhiyong, Goldstein, Adrian, Zong, Rui-Ting, Lin, Danjun, Neufeld, Ellis J., Scheuermann, Richard H., ...
Nuclear matrix attachment regions (MARs) flanking the immunoglobulin heavy chain intronic enhancer (Eμ) are the targets of the negative regulator, NF-μNR, found in non-B and early pre-B cells....
Mathur, Mukul, Tucker, Philip W., Samuels, Herbert H.
Members of the type II nuclear hormone receptor subfamily (e.g., thyroid hormone receptors [TRs], retinoic acid receptors, retinoid X receptors [RXRs], vitamin D receptor, and the peroxisome...
Zong, Rui-Ting, Das, Chhaya, Tucker, Philip W.
Bright (B cell regulator of IgH transcription) transactivates the immunoglobulin heavy chain (IgH) intronic enhancer, Eµ, by binding to matrix attachment regions (MARs), sites necessary for DNA...
Emili, Andrew, Shales, Michael, McCracken, Susan, Xie, Weijun, Tucker, Philip W, Kobayashi, Ryuji, ...
The carboxyl-terminal domain (CTD) of the largest subunit of eukaryotic RNA polymerase II (pol II) plays an important role in promoting steps of pre-mRNA processing. To identify proteins in human...
Kim, Dongkyoon, Tucker, Philip W.
Bright/ARID3a has been implicated in mitogen- and growth factor-induced up-regulation of immunoglobulin heavy-chain (IgH) genes and in E2F1-dependent G1/S cell cycle progression. For IgH...
Mathur, Shawn, Schmidt, Christian, Das, Chhaya, Tucker, Philip W
Uncensored exchange of scientific results hastens progress. Open Access does not stop at the removal of price and permission barriers; still, censorship and reading disabilities, to name a few,...
Wang, Zhiyong, Goldstein, Adrian, Zong, Rui-Ting, Lin, Danjun, Neufeld, Ellis J., Scheuermann, Richard H., ...
Nuclear matrix attachment regions (MARs) flanking the immunoglobulin heavy chain intronic enhancer (Eμ) are the targets of the negative regulator, NF-μNR, found in non-B and early pre-B cells....
Mathur, Mukul, Tucker, Philip W., Samuels, Herbert H.
Members of the type II nuclear hormone receptor subfamily (e.g., thyroid hormone receptors [TRs], retinoic acid receptors, retinoid X receptors [RXRs], vitamin D receptor, and the peroxisome...
Zong, Rui-Ting, Das, Chhaya, Tucker, Philip W.
Bright (B cell regulator of IgH transcription) transactivates the immunoglobulin heavy chain (IgH) intronic enhancer, Eµ, by binding to matrix attachment regions (MARs), sites necessary for DNA...
Emili, Andrew, Shales, Michael, McCracken, Susan, Xie, Weijun, Tucker, Philip W, Kobayashi, Ryuji, ...
The carboxyl-terminal domain (CTD) of the largest subunit of eukaryotic RNA polymerase II (pol II) plays an important role in promoting steps of pre-mRNA processing. To identify proteins in human...
Kim, Dongkyoon, Tucker, Philip W.
Bright/ARID3a has been implicated in mitogen- and growth factor-induced up-regulation of immunoglobulin heavy-chain (IgH) genes and in E2F1-dependent G1/S cell cycle progression. For IgH...
Mathur, Shawn, Schmidt, Christian, Das, Chhaya, Tucker, Philip W
Uncensored exchange of scientific results hastens progress. Open Access does not stop at the removal of price and permission barriers; still, censorship and reading disabilities, to name a few,...
NPM/ALK binds and phosphorylates the RNA/DNA-binding protein PSF in anaplastic large-cell lymphoma
Galietta, Annamaria, Gunby, Rosalind H., Redaelli, Sara, Stano, Paola, Carniti, Cristiana, Bachi, Angela, ...
The oncogenic fusion tyrosine kinase nucleophosmin/anaplastic lymphoma kinase (NPM/ALK) induces cellular transformation in anaplastic large-cell lymphomas (ALCLs) carrying the t(2;5) chromosomal...